Reliability of individual functional MRI brain mapping of language.

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Date publication

juillet 2005

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques


Tous les auteurs :
Otzenberger H, Gounot D, Marrer C, Namer IJ, Metz-Lutz MN

Résumé

The use of individual brain mapping for a single case study implicitly assumes that the pattern of activation obtained in a single session represents the subject's functional neuroanatomy. It is therefore essential to estimate the potential variability of brain activation in individuals. To this purpose, the authors compared the pattern of activation determined by statistical parametric mapping (SPM 99) in 9 subjects who repeated 3 verbal tasks in 3 separate sessions. In each subject for each task, the authors examined the intersession variability of the volume of activation in a set of regions classically implicated in language processing. Their results show that reproducibility of functional MRI brain mapping for language within subject varies as a function of the activation task and the region of interest for language.

Référence

Neuropsychology. 2005 Jul;19(4):484-93.