[Increased nuchal translucency and cystic hygroma in the first trimester: prenatal diagnosis and neonatal outcome].
Fiche publication
Date publication
octobre 2005
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GAILLARD Dominique, Pr GRAESSLIN Olivier
Tous les auteurs :
Ducarme G, Graesslin O, Alanio E, Bige V, Gaillard D, Gabriel R
Lien Pubmed
Résumé
OBJECTIVE: A prospective study of pregnancy outcome in fetuses with increased nuchal translucency above the 95th centile (group NT) or cystic hygroma (group CH) at 10 to 14 weeks of gestation was performed. PATIENTS AND METHODS: Maternal and fetal data (nuchal translucency, caryotype, pregnancy outcome) and infant follow-up of 223 fetuses with first trimester nuchal translucency thickness (183 NT and 40 CH) were analysed. RESULTS: The measurement of nuchal translucency thickness shows a significant difference between group CH and NT (7.4+/-2.9 mm compared 3.7+/-0.8 mm). Chromosomal abnormalities were present in 55% (22/40) in group CH, with 9 cases/22 (40.9%) of Turner syndrome, compared with 14.2% (26/183) in group NT with trisomy 21 in 15 cases/26 (57.7%) (P
Référence
Gynecol Obstet Fertil. 2005 Oct;33(10):750-4.