[Conformal radiation therapy with or without intensity modulation in the treatment of localized prostate cancer].
Fiche publication
Date publication
novembre 2005
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PEIGNAUX Karine, Pr TRUC Gilles
Tous les auteurs :
Maingon P, Bolla M, Truc G, Bosset M, Peignaux K, Ammor A
Lien Pubmed
Résumé
Conformal radiation therapy has now to be considered as a standard treatment of localized prostatic adenocarcinomas. Using conformational methods and intensity modulated radiation therapy requires a rigorous approach for their implementation in routine, focused on the reproducibility of the treatment, target volume definitions, dosimetry, quality control, setup positioning. In order to offer to the largest number of patients high-dose treatment, the clinicians must integrate as prognostic factors accurate definition of microscopic extension as well as the tolerance threshold of critical organs. High-dose delivery is expected to be most efficient in intermediary risks and locally advanced diseases. Intensity modulated radiation therapy is specifically dedicated to dose escalation. Perfect knowledge of classical constraints of conformal radiation therapy is required. Using such an approach in routine needs a learning curve including the physicists and a specific quality assurance program.
Référence
Cancer Radiother. 2005 Nov;9(6-7):382-7