Respiratory motion artefact in the liver dome on FDG PET/CT: comparison of attenuation correction with CT and a caesium external source.

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Date publication

décembre 2005

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PAPATHANASSIOU Dimitri


Tous les auteurs :
Papathanassiou D, Becker S, Amir R, Meneroux B, Liehn JC

Résumé

PURPOSE: Respiratory motion has been reported to be a potential cause of artefacts on PET/CT, and of errors in the quantification of lesion activity due to inaccurate attenuation correction. We examined FDG images corrected for attenuation with CT and a caesium external source in the same patients to study this artefact and to assess its impact on detection of lesions in the upper part of the liver. METHODS: A total of 122 patients underwent the examination using both attenuation correction techniques, with the Gemini PET/CT scanner. No breathing instructions were given. The images obtained were visually compared, and standardised uptake values (SUVs) in 35 lesions were measured (mean SUV/normal liver SUV) in 14 patients with lesions in the upper part of the liver (less than 5 cm from the upper border). RESULTS: CT-corrected images of the liver included an artefactual cold area in 84 patients (69%); this area was located in the posterior upper part of the liver (65 patients, 53%), included the top of the liver (ten patients, 8%) or affected both the top and the posterior part (nine patients, 8%). In lesions (and also in normal liver outside the artefactual area), SUVs obtained with CT correction were higher than those obtained with Cs correction (p

Référence

Eur J Nucl Med Mol Imaging. 2005 Dec;32(12):1422-8