Is there any relationship between pernicious anemia and iron deficiency?
Fiche publication
Date publication
novembre 2006
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CADIOT Guillaume, Pr JOLLY Damien, Pr THIEFIN Gérard
Tous les auteurs :
Lagarde S, Jovenin N, Diebold MD, Jaussaud R, Cahn V, Bertin E, Jolly D, Thiefin G, Cadiot G
Lien Pubmed
Résumé
INTRODUCTION: Previous studies have suggested that iron deficiency could be due to atrophic gastritis of the body/fundus. The aim of this study was to determine the prevalence of iron deficiency among patients with pernicious anemia and associated factors. PATIENTS AND METHODS: All patients with pernicious anemia diagnosed at our institution between January 1990 and February 2005 were included. Inclusion criteria were: 1- histological diagnosis of atrophic fundic gastritis and 2- criteria of gastric autoimmune involvement. Histology of gastric biopsies was performed in a blinded manner. Iron deficiency was defined as serum ferritin level
Référence
Gastroenterol Clin Biol. 2006 Nov;30(11):1245-9.