Nitric oxide-induced resistance or sensitization to death in tumor cells.
Fiche publication
Date publication
septembre 2008
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BETTAIEB Ali
Tous les auteurs :
Jeannin JF, Leon L, Cortier M, Sassi N, Paul C, Bettaieb A
Lien Pubmed
Résumé
This report summarizes the present state of our knowledge pertaining to the NO-induced resistance or sensitization of tumor cell death. The effects of NO and its synergy with members of the TNF family, with cytotoxic drugs, and with ionizing radiations have been investigated. The dual effect of NO-induced resistance or sensitization and the underlying molecular mechanisms are discussed.
Référence
Nitric Oxide. 2008 Sep;19(2):158-63