Surgical strategy in locally advanced and metastatic renal cell carcinoma
Fiche publication
Date publication
mai 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LANG Hervé
Tous les auteurs :
Patard JJ, Culine S, Ravaud A, Lang H
Lien Pubmed
Résumé
Radical nephrectomy with total surgical removal remains the standard treatment for locally advanced renal cell carcinoma (RCC) in 2009. In the majority of cases such surgery is performed via an open route while it sometimes necessitates the involvement of a multidisciplinary team. Adjuvant and neo-adjuvant strategies using anti-angiogenic drugs are currently emerging. Clinical trials are ongoing for validating these new approaches. In the metastatic setting, radical nephrectomy followed by systemic treatment is currently the standard treatment. However, this concept is now being challenged due to the efficacy of anti-angiogenic drugs on the primary tumour.
Référence
Oncologie. 2009 May;11(5):272-7