Tunable antibacterial coatings that support mammalian cell growth.
Fiche publication
Date publication
janvier 2010
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ANSELME Karine
Tous les auteurs :
Vasilev K, Sah V, Anselme K, Ndi C, Mateescu M, Dollmann B, Martinek P, Ys H, Ploux L, Griesser HJ
Lien Pubmed
Résumé
Bacterial infections present an enormous problem causing human suffering and cost burdens to healthcare systems worldwide. Here we present novel tunable antibacterial coatings which completely inhibit bacterial colonization by Staphylococcus epidermidis but allow normal adhesion and spreading of osteoblastic cells. The coatings are based on amine plasma polymer films loaded with silver nanoparticles. The method of preparation allows flexible control over the amount of loaded silver nanoparticles and the rate of release of silver ions.
Référence
Nano Lett. 2010 Jan;10(1):202-7.