Berico P, Nogaret M, Cigrang M, Lallement A, Vand-Rajabpour F, Flores-Yanke A, Gambi G, Davidson G, Seno L, Obid J, Vokshi BH, Le Gras S, Mengus G, Ye T, Cordero CF, Dalmasso M, Compe E, Bertolotto C, Hernando E, Davidson I, Coin F

Cell Rep. 2023 11 2;42(11):113363

Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress.

Sandoz J, Cigrang M, Zachayus A, Catez P, Donnio LM, Elly C, Nieminuszczy J, Berico P, Braun C, Alekseev S, Egly JM, Niedzwiedz W, Giglia-Mari G, Compe E, Coin F

Nat Commun. 2023 01 20;14(1):341

Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions.

Compe E, Pangou E, Le May N, Elly C, Braun C, Hwang JH, Coin F, Sumara I, Choi KW, Egly JM

Sci Adv. 2022 08 19;8(33):eabp9457

Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells.

Costanzo F, Martínez Diez M, Santamaría Nuñez G, Díaz-Hernandéz JI, Genes Robles CM, Díez Pérez J, Compe E, Ricci R, Li TK, Coin F, Martínez Leal JF, Garrido-Martin EM, Egly JM

EMBO Mol Med. 2022 Mar 9;:e14841

CDK7 and MITF repress a transcription program involved in survival and drug tolerance in melanoma.

Berico P, Cigrang M, Davidson G, Braun C, Sandoz J, Legras S, Vokshi BH, Slovic N, Peyresaubes F, Gene Robles CM, Egly JM, Compe E, Davidson I, Coin F

EMBO Rep. 2021 Jul 23;:e51683

Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome.

Epanchintsev A, Rauschendorf MA, Costanzo F, Calmels N, Obringer C, Sarasin A, Coin F, Laugel V, Egly JM

Sci Rep. 2020 Jan 24;10(1):1105

A chromatin scaffold for DNA damage recognition: how histone methyltransferases prime nucleosomes for repair of ultraviolet light-induced lesions.

Gsell C, Richly H, Coin F, Naegeli H

Nucleic Acids Res.. 2020 Jan 13;:

DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcription.

Semer M, Bidon B, Larnicol A, Caliskan G, Catez P, Egly JM, Coin F, Le May N

Nat. Chem. Biol.. 2019 Sep 16;:

TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription.

Compe E, Genes CM, Braun C, Coin F, Egly JM

Nat Commun. 2019 May 7;10(1):2084

Activation of P-TEFb by RBM7: To Live or Let Die.

Le May N, Coin F

Mol. Cell. 2019 Apr 18;74(2):223-224

Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression.

Sandoz J, Nagy Z, Catez P, Caliskan G, Geny S, Renaud JB, Concordet JP, Poterszman A, Tora L, Egly JM, Le May N, Coin F

Nat Commun. 2019 Mar 20;10(1):1288

SerpinB2 is involved in cellular response upon UV irradiation.

Majoros H, Ujfaludi Z, Borsos BN, Hudacsek VV, Nagy Z, Coin F, Buzas K, Kovács I, Bíró T, Boros IM, Pankotai T

Sci Rep. 2019 Feb 26;9(1):2753

Conducting the CTD orchestra.

Genes Robles CM, Coin F

Nat. Chem. Biol.. 2018 Dec 31;:

XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.

Bidon B, Iltis I, Semer M, Nagy Z, Larnicol A, Cribier A, Benkirane M, Coin F, Egly JM, Le May N

Nat Commun. 2018 Jul 4;9(1):2610

Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation.

Epanchintsev A, Costanzo F, Rauschendorf MA, Caputo M, Ye T, Donnio LM, Proietti-de-Santis L, Coin F, Laugel V, Egly JM

Mol. Cell. 2017 Dec 21;68(6):1054-1066.e6

Unified promoter opening steps in eukaryotic gene expression.

Sandoz J, Coin F

Oncotarget. 2017 Oct 17;8(49):84614-84615

Is TFIIH the new Achilles heel of cancer cells?

Berico P, Coin F

Transcription. 2017 Aug;:0

Transcription without XPB Establishes a Unified Helicase-Independent Mechanism of Promoter Opening in Eukaryotic Gene Expression.

Alekseev S, Nagy Z, Sandoz J, Weiss A, Egly JM, Le May N, Coin F

Mol. Cell. 2017 Feb;65(3):504-514.e4

Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.

Santamaría Nuñez G, Robles CM, Giraudon C, Martínez-Leal JF, Compe E, Coin F, Aviles P, Galmarini CM, Egly JM

Mol. Cancer Ther.. 2016 Oct;15(10):2399-2412

The DNA surgery honored with a Nobel prize

Coin F

Rev Prat. 2016 Feb 20;66(2):226-228

Revisiting the Function of CDK7 in Transcription by Virtue of a Recently Described TFIIH Kinase Inhibitor.

Coin F, Egly JM

Mol Cell. 2015 Aug 20;59(4):513-4

Orchestral maneuvers at the damaged sites in nucleotide excision repair.

Alekseev S, Coin F

Cell Mol Life Sci. 2015 Jun;72(11):2177-86

Correction: ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor.

Tomita T, Ieguchi K, Coin F, Kato Y, Kikuchi H, Oshima Y, Kurata S, Maru Y

PLoS One. 2015 Sep 11;10(9):e0138262

Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin.

Ziani S, Nagy Z, Alekseev S, Soutoglou E, Egly JM, Coin F

J Cell Biol. 2014 Sep 1;206(5):589-98

A small molecule screen identifies an inhibitor of DNA repair inducing the degradation of TFIIH and the chemosensitization of tumor cells to platinum.

Alekseev S, Ayadi M, Brino L, Egly JM, Larsen AK, Coin F

Chem Biol. 2014 Mar 20;21(3):398-407

ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.

Mourgues S, Gautier V, Lagarou A, Bordier C, Mourcet A, Slingerland J, Kaddoum L, Coin F, Vermeulen W, Gonzales de Peredo A, Monsarrat B, Mari PO, Giglia-Mari G

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17927-32

Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stress.

Kristensen U, Epanchintsev A, Rauschendorf MA, Laugel V, Stevnsner T, Bohr VA, Coin F, Egly JM

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2261-70

Sirt1 suppresses RNA synthesis after UV irradiation in combined xeroderma pigmentosum group D/Cockayne syndrome (XP-D/CS) cells.

Velez-Cruz R, Zadorin AS, Coin F, Egly JM

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):E212-20

DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.

Fregoso M, Laine JP, Aguilar-Fuentes J, Mocquet V, Reynaud E, Coin F, Egly JM, Zurita M

Mol Cell Biol. 2007 May;27(10):3640-50

Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair.

Coin F, Oksenych V, Egly JM

Mol Cell. 2007 Apr 27;26(2):245-56.

Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy.

Vitorino M, Coin F, Zlobinskaya O, Atkinson RA, Moras D, Egly JM, Poterszman A, Kieffer B

J Mol Biol. 2007 Apr 27;368(2):473-80

XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients.

Ito S, Kuraoka I, Chymkowitch P, Compe E, Takedachi A, Ishigami C, Coin F, Egly JM, Tanaka K

Mol Cell. 2007 Apr 27;26(2):231-43.

Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.

Andressoo JO, Jans J, de Wit J, Coin F, Hoogstraten D, van de Ven M, Toussaint W, Huijmans J, Thio HB, van Leeuwen WJ, de Boer J, Egly JM, Hoeijmakers JH, van der Horst GT, Mitchell JR

PLoS Biol. 2006 Oct;4(10):e322.

p8/TTD-A as a repair-specific TFIIH subunit.

Coin F, Proietti De Santis L, Nardo T, Zlobinskaya O, Stefanini M, Egly JM

Mol Cell. 2006 Jan 20;21(2):215-26.