Détail d'une personne de l'annuaire - fr | Cancéropôle Est, la recherche innovante dans la lutte contre le cancer

Denaturing mass photometry for rapid optimization of chemical protein-protein cross-linking reactions.

Gizardin-Fredon H, Santo PE, Chagot ME, Charpentier B, Bandeiras TM, Manival X, Hernandez-Alba O, Cianférani S

Nat Commun. 2024 04 25;15(1):3516

Extract2Chip-Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance.

Paiva ACF, Lemos AR, Busse P, Martins MT, Silva DO, Freitas MC, Santos SP, Freire F, Barrey EJ, Manival X, Koetzner L, Heinrich T, Wegener A, Grädler U, Bandeiras TM, Schwarz D, Sousa PMF

Biosensors (Basel). 2023 10 5;13(10):

[A new mechanism of control of miRNA maturation?]

Virciglio C, Manival X, Rederstorff M

Med Sci (Paris). 2022 09 12;38(8-9):629-631

Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases.

Dos Santos Morais R, Santo PE, Ley M, Schelcher C, Abel Y, Plassart L, Deslignière E, Chagot ME, Quinternet M, Paiva ACF, Hessmann S, Morellet N, M F Sousa P, Vandermoere F, Bertrand E, Charpentier B, Bandeiras TM, Plisson-Chastang C, Verheggen C, Cianférani S, Manival X

J Mol Biol. 2022 07 25;:167760

The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.

Abel Y, Charron C, Virciglio C, Bourguignon-Igel V, Quinternet M, Chagot ME, Robert MC, Verheggen C, Branlant C, Bertrand E, Manival X, Charpentier B, Rederstorff M

Nucleic Acids Res. 2022 Feb 12;:

The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity.

Bragantini B, Charron C, Bourguet M, Paul A, Tiotiu D, Rothé B, Marty H, Terral G, Hessmann S, Decourty L, Chagot ME, Strub JM, Massenet S, Bertrand E, Quinternet M, Saveanu C, Cianférani S, Labialle S, Manival X, Charpentier B

Nat Commun. 2021 03 25;12(1):1859

Optimizing the First TPR Domain of the Human SPAG1 Protein Provides Insight into the HSP70 and HSP90 Binding Properties.

Dermouche S, Chagot ME, Manival X, Quinternet M

Biochemistry. 2021 Mar 19;:

Application of NMR Spectroscopy to Determine the 3D Structure of Small Non-Coding RNAs.

Chagot ME, Quinternet M, Manival X, Lebars I

Methods Mol Biol. 2021 ;2300:251-266

NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis.

Abel Y, Paiva ACF, Bizarro J, Chagot ME, Santo PE, Robert MC, Quinternet M, Vandermoere F, Sousa PMF, Fort P, Charpentier B, Manival X, Bandeiras TM, Bertrand E, Verheggen C

Nucleic Acids Res. 2020 Dec 24;:

Synergistic defects in pre-rRNA processing from mutations in the U3-specific protein Rrp9 and U3 snoRNA.

Clerget G, Bourguignon-Igel V, Marmier-Gourrier N, Rolland N, Wacheul L, Manival X, Charron C, Kufel J, Méreau A, Senty-Ségault V, Tollervey D, Lafontaine DLJ, Branlant C, Rederstorff M

Nucleic Acids Res.. 2020 Apr 17;48(7):3848-3868

Box C/D snoRNPs: solid-state NMR fingerprint of an early-stage 50 kDa assembly intermediate.

Chagot ME, Quinternet M, Jacquemin C, Manival X, Gardiennet C

Biomol NMR Assign. 2020 Feb 6;:

Binding properties of the quaternary assembly protein SPAG1.

Chagot ME, Dos Santos Morais R, Dermouche S, Lefebvre D, Manival X, Chipot C, Dehez F, Quinternet M

Biochem. J.. 2019 May 22;:

The yeast C/D box snoRNA U14 adopts a "weak" K-turn like conformation recognized by the Snu13 core protein in solution.

Chagot ME, Quinternet M, Rothé B, Charpentier B, Coutant J, Manival X, Lebars I

Biochimie. 2019 Mar 23;:

Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.

Henri J, Chagot ME, Bourguet M, Abel Y, Terral G, Maurizy C, Aigueperse C, Georgescauld F, Vandermoere F, Saint-Fort R, Behm-Ansmant I, Charpentier B, Pradet-Balade B, Verheggen C, Bertrand E, Meyer P, Cianférani S, Manival X, Quinternet M

Structure. 2018 Jul 18;:

The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.

Maurizy C, Quinternet M, Abel Y, Verheggen C, Santo PE, Bourguet M, C F Paiva A, Bragantini B, Chagot ME, Robert MC, Abeza C, Fabre P, Fort P, Vandermoere F, M F Sousa P, Rain JC, Charpentier B, Cianférani S, Bandeiras TM, Pradet-Balade B, Manival X, Bertrand E

Nat Commun. 2018 May 29;9(1):2093

NMR assignment and solution structure of the external DII domain of the yeast Rvb2 protein.

Bragantini B, Rouillon C, Charpentier B, Manival X, Quinternet M

Biomol NMR Assign. 2018 Mar 22;:

Implication of the box C/D snoRNP assembly factor Rsa1p in U3 snoRNP assembly.

Rothé B, Manival X, Rolland N, Charron C, Senty-Ségault V, Branlant C, Charpentier B

Nucleic Acids Res.. 2017 May;:

Carbohydrate-based peptidomimetics targeting neuropilin-1: Synthesis, molecular docking study and in vitro biological activities.

Richard M, Chateau A, Jelsch C, Didierjean C, Manival X, Charron C, Maigret B, Barberi-Heyob M, Chapleur Y, Boura C, Pellegrini-Moïse N

Bioorg. Med. Chem.. 2016 Nov;24(21):5315-5325

Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species.

Quinternet M, Chagot ME, Rothé B, Tiotiu D, Charpentier B, Manival X

Structure. 2016 Oct;24(10):1693-1706

Functional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP Biogenesis.

Bragantini B, Tiotiu D, Rothé B, Saliou JM, Marty H, Cianférani S, Charpentier B, Quinternet M, Manival X

J. Mol. Biol.. 2016 Jun;428(11):2488-506

Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly.

Quinternet M, Rothe B, Barbier M, Bobo C, Saliou JM, Jacquemin C, Back R, Chagot ME, Cianferani S, Meyer P, Branlant C, Charpentier B, Manival X

J Mol Biol. 2015 Aug 28;427(17):2816-39

(1)H, (15)N and (13)C resonance assignments of the two TPR domains from the human RPAP3 protein.

Chagot ME, Jacquemin C, Branlant C, Charpentier B, Manival X, Quinternet M

Biomol NMR Assign. 2015 Apr;9(1):99-102

(1)H, (15)N and (13)C resonance assignments of the yeast Pih1 and Tah1 C-terminal domains complex.

Manival X, Jacquemin C, Charpentier B, Quinternet M

Biomol NMR Assign. 2015 Apr;9(1):71-3

Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity.

Saliou JM, Manival X, Tillault AS, Atmanene C, Bobo C, Branlant C, Van Dorsselaer A, Charpentier B, Cianferani S

Proteomics. 2015 Feb 27

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.

Bizarro J, Charron C, Boulon S, Westman B, Pradet-Balade B, Vandermoere F, Chagot ME, Hallais M, Ahmad Y, Leonhardt H, Lamond A, Manival X, Branlant C, Charpentier B, Verheggen C, Bertrand E

J Cell Biol. 2014 Nov 24;207(4):463-80

Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly.

Rothe B, Back R, Quinternet M, Bizarro J, Robert MC, Blaud M, Romier C, Manival X, Charpentier B, Bertrand E, Branlant C

Nucleic Acids Res. 2014 Feb;42(3):2015-36

Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction.

Rothe B, Saliou JM, Quinternet M, Back R, Tiotiu D, Jacquemin C, Loegler C, Schlotter F, Pena V, Eckert K, Morera S, Dorsselaer AV, Branlant C, Massenet S, Sanglier-Cianferani S, Manival X, Charpentier B

Nucleic Acids Res. 2014;42(16):10731-47

High-resolution structural analysis shows how Tah1 tethers Hsp90 to the R2TP complex.

Back R, Dominguez C, Rothe B, Bobo C, Beaufils C, Morera S, Meyer P, Charpentier B, Branlant C, Allain FH, Manival X

Structure. 2013 Oct 8;21(10):1834-47

Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity.

Manival X, Charron C, Fourmann JB, Godard F, Charpentier B, Branlant C

Nucleic Acids Res. 2006 Feb 2;34(3):826-39. Print 2006.

The archaeal sRNA binding protein L7Ae has a 3D structure very similar to that of its eukaryal counterpart while having a broader RNA-binding specificity.

Charron C, Manival X, Clery A, Senty-Segault V, Charpentier B, Marmier-Gourrier N, Branlant C, Aubry A

J Mol Biol. 2004 Sep 17;342(3):757-73.

Dr MANIVAL Xavier

Fiche personne

coordonnées

Territoire

Statut

affiliation

équipes/plateformes

Recherche

Publications