Witz A, Conroy T, Lambert A, Salleron J, Diallo A, Husson M, Nicolle R, Hammel P, Biagi J, Renouf DJ, Turpin A, Richard C, Bachet JB, Iovanna J, Dusetti N, Monard L, Mauduit M, Cros J, Harlé A

J Clin Oncol. 2026 08 3;:JCO2502508

Evaluation of the Idylla IDH1-2 Mutation Assay for the Detection of IDH Variants in Solid Tumors and Hematological Malignancies

Gilson P, Muller M, Gauchotte G, Fadil S, Husson M, Hanriot I, Witz A, Dardare J, Betz M, Merlin JL, Harlé A

Int J Mol Sci. 2026 01 20;27(2):

Radiotherapy in the management of PDAC, from past to present.

Dardare J, Martz N, Witz A, Betz M, Michel C, Gilson P, Merlin JL, Lambert A, Harle A

Transl Oncol. 2025 12 8;63:102632

Improving Radiation Therapy in Pancreatic Cancer Through Radiosensitization Strategies.

Dardare J, Martz N, Witz A, Betz M, Michel C, Gilson P, Merlin JL, Lambert A, Harle A

Int J Radiat Oncol Biol Phys. 2025 09 16;:

A novel ddPCR assay for BRCA1 and RAD51C methylation: Advancing HRD Detection in Ovarian Cancer.

Michel C, Simon A, Witz A, Hanriot I, Dardare J, Betz M, Brun M, Gilson P, Merlin JL, Harlé A

J Mol Diagn. 2025 08 7;:

Homologous recombination deficiency (HRD) testing landscape: clinical applications and technical validation for routine diagnostics.

Witz A, Dardare J, Betz M, Michel C, Husson M, Gilson P, Merlin JL, Harlé A

Biomark Res. 2025 02 21;13(1):31

Decoding mutational signatures in breast cancer: Insights from a multi-cohort study.

Betz M, Witz A, Dardare J, Michel C, Massard V, Boidot R, Gilson P, Merlin JL, Harlé A

Transl Oncol. 2025 02 4;53:102315

DDB2 expression lights the way for precision radiotherapy response in PDAC cells, with or without olaparib.

Dardare J, Witz A, Betz M, François A, Lamy L, Husson M, Demange J, Rouyer M, Lambert A, Merlin JL, Gilson P, Harlé A

Cell Death Discov. 2024 09 27;10(1):411

REGN5093-M114: can an antibody-drug conjugate overcome the challenge of resistance to epidermal growth factor receptor and mesenchymal epithelial transition tyrosine kinase inhibitors in non-small cell lung cancer?

Dardare J, Witz A, Harlé A

Transl Lung Cancer Res. 2024 08 31;13(8):2082-2086

Tumor-derived cell-free DNA and circulating tumor cells: partners or rivals in metastasis formation?

Witz A, Dardare J, Betz M, Gilson P, Merlin JL, Harlé A

Clin Exp Med. 2024 01 17;24(1):2

CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines.

Witz A, Dardare J, Francois A, Husson M, Rouyer M, Demange J, Merlin JL, Gilson P, Harlé A

Sci Rep. 2023 10 31;13(1):18741

Gene Mutations and Liquid Biopsy in ER-Positive Breast Cancers: A Small Step Forward, a Giant Leap for Personalization of Endocrine Therapy?

Betz M, Massard V, Gilson P, Witz A, Dardare J, Harlé A, Merlin JL

Cancers (Basel). 2023 10 27;15(21):

Validation of the Idylla GeneFusion assay to detect fusions and MET exon-skipping in non-small cell lung cancers.

Gilson P, Pouget C, Belmonte R, Fadil S, Demange J, Rouyer M, Lacour J, Betz M, Dardare J, Witz A, Merlin JL, Harlé A

Sci Rep. 2023 08 9;13(1):12909

DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy.

Dardare J, Witz A, Betz M, Francois A, Meras M, Lamy L, Lambert A, Grandemange S, Husson M, Rouyer M, Demange J, Merlin JL, Harlé A, Gilson P

Front Oncol. 2022 12 8;12:1052163

Epithelial to Mesenchymal Transition in Patients with Pancreatic Ductal Adenocarcinoma: State-of-the-Art and Therapeutic Opportunities.

Dardare J, Witz A, Merlin JL, Bochnakian A, Toussaint P, Gilson P, Harlé A

Pharmaceuticals (Basel). 2021 Jul 29;14(8):

SMAD4 and the TGFβ Pathway in Patients with Pancreatic Ductal Adenocarcinoma.

Dardare J, Witz A, Merlin JL, Gilson P, Harlé A

Int J Mol Sci. 2020 May 16;21(10):

Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer.

Franczak C, Witz A, Geoffroy K, Demange J, Rouyer M, Husson M, Massard V, Gavoille C, Lambert A, Gilson P, Gambier N, Scala-Bertola J, Merlin JL, Harlé A

PLoS ONE. 2020 ;15(1):e0227294