Fiche publication
Date publication
février 2025
Journal
Translational oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOIDOT Romain
,
Pr HARLE Alexandre
,
Pr MERLIN Jean-Louis
,
Dr GILSON Pauline
,
Dr MASSARD Vincent
Tous les auteurs :
Betz M, Witz A, Dardare J, Michel C, Massard V, Boidot R, Gilson P, Merlin JL, Harlé A
Lien Pubmed
Résumé
Diagnosis and treatment decisions of hormonal breast cancers (BC) are now guided by genomic mutations determination, combined into mutational signatures, and provide insight into the patients' genomic landscape. This work aims to compare genomic data and signatures extracted from tissue samples collected in the CICLADES study to existing cohorts. Ultimately, the goal is to prove the accuracy of smaller cohorts and provide new relevant data.
Mots clés
Breast cancer, Genomic database, Mutational signature, Next generation sequencing
Référence
Transl Oncol. 2025 02 4;53:102315
