Dr GRUTTER Thomas

Fiche personne

Coordonnées

Laboratoire CBST
Faculté de Pharmacie
74 route du Rhin
BP 60024
67401 ILLIRCH Cedex

Territoire

Alsace

Statut

Chercheur

Affiliation

Laboratoire de chémo-biologie synthétique & thérapeutique - UMR 7199 (CBST)

Équipes/plateformes

UMR 7199 - Equipe "Ingénierie canaux ioniques"

Publications

Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice.

Gilabert D, Duveau A, Carracedo S, Linck N, Langla A, Muramatsu R, Koch-Nolte F, Rassendren F, Grutter T, Fossat P, Boué-Grabot E, Ulmann L

iScience. 2023 11 17;26(11):108110

Untangling Macropore Formation and Current Facilitation in P2X7.

Cevoli F, Arnould B, Peralta FA, Grutter T

Int J Mol Sci. 2023 06 30;24(13):

Optical control of PIEZO1 channels.

Peralta FA, Balcon M, Martz A, Biljali D, Cevoli F, Arnould B, Taly A, Chataigneau T, Grutter T

Nat Commun. 2023 03 7;14(1):1269

Comparing transmembrane protein structures with ATOLL.

Jacquemard C, Bret G, Grutter T, Kellenberger E

Bioinformatics. 2022 03 4;38(6):1743-1744

Photo-isomerizable tweezers to probe ionotropic receptor mechanisms.

Peverini L, Dunning K, Peralta FA, Grutter T

Curr Opin Pharmacol. 2022 02;62:109-116

Using Symmetrical Organic Cation Solutions to Study P2X7 Ion Permeation.

Dunning K, Peverini L, Grutter T

Methods Mol Biol. 2022 ;2510:239-252

P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation.

Dunning K, Martz A, Peralta FA, Cevoli F, Boué-Grabot E, Compan V, Gautherat F, Wolf P, Chataigneau T, Grutter T

Int J Mol Sci. 2021 06 18;22(12):

Update of P2X receptor properties and their pharmacology: IUPHAR Review 30.

Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F

Br J Pharmacol. 2021 02;178(3):489-514

P2X-GCaMPs as Versatile Tools for Imaging Extracellular ATP Signaling.

Ollivier M, Beudez J, Linck N, Grutter T, Compan V, Rassendren F

eNeuro. 2021 01 28;8(1):

Manipulation of ion channel gating with photoswitchable tweezers.

Dunning K, Grutter T

Methods Enzymol. 2021 01 27;653:349-376

Molecular determinants for agonist recognition and discrimination in P2X2 receptors.

Gasparri F, Wengel J, Grutter T, Pless SA

J Gen Physiol. 2019 07 1;151(7):898-911

New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors.

Peverini L, Beudez J, Dunning K, Chataigneau T, Grutter T

Front Mol Neurosci. 2018 07 31;11:265

P2X2 Dominant Deafness Mutations Have No Negative Effect on Wild-Type Isoform: Implications for Functional Rescue and in Deafness Mechanism.

Zhu Y, Beudez J, Yu N, Grutter T, Zhao HB

Front Mol Neurosci. 2017 11 13;10:371

On the permeation of large organic cations through the pore of ATP-gated P2X receptors.

Harkat M, Peverini L, Cerdan AH, Dunning K, Beudez J, Martz A, Calimet N, Specht A, Cecchini M, Chataigneau T, Grutter T

Proc. Natl. Acad. Sci. U.S.A.. 2017 05 9;114(19):E3786-E3795

Molecular structure and function of P2X receptors.

Habermacher C, Dunning K, Chataigneau T, Grutter T

Neuropharmacology. 2016 05;104:18-30

Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel.

Habermacher C, Martz A, Calimet N, Lemoine D, Peverini L, Specht A, Cecchini M, Grutter T

Elife. 2016 Jan 25;5:e11050

Architectural and functional similarities between trimeric ATP-gated P2X receptors and acid-sensing ion channels.

Kellenberger S, Grutter T

J Mol Biol. 2015 01 16;427(1):54-66

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