Fiche publication
Date publication
mars 2022
Journal
Bioinformatics (Oxford, England)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GRUTTER Thomas
Tous les auteurs :
Jacquemard C, Bret G, Grutter T, Kellenberger E
Lien Pubmed
Résumé
The 3D structure of transmembrane helices plays a key role in the function of membrane proteins. While visual inspection can usually discern the distinctive features of a helix bundle, simply translating them into a 2D diagram can be difficult. ATOLL (Aligned Transmembrane dOmains Layout fLattening) projects the helix bundle onto the lipid bilayer plane, thereby facilitating the comparison of different structures of the same membrane protein or structures of different membrane proteins.
Mots clés
Software, Computers, Membrane Proteins
Référence
Bioinformatics. 2022 03 4;38(6):1743-1744