Gensbittel V, Yesilata Z, Bochler L, Follain G, Nemoz-Billet L, Lefebvre O, Uhlmann K, Larnicol A, Ammirati GEM, Harlepp S, Goswami R, Girardo S, Paulen L, Hyenne V, Mittelheisser V, Stemmelen T, Molitor A, Carapito R, Belthier G, Pannequin J, Kräter M, Müller DJ, Balzani D, Guck J, Osmani N, Goetz JG

Nat Mater. 2026 01 19;:

Serum albumin-coated stellate mesoporous silica nanocomposites inhibit metastatic outgrowth in zebrafish embryos.

Asokan N, Mittelheisser V, Jablonski A, Adam A, Bizeau J, Harlepp S, Hyenne V, Lefebvre O, Goetz JG, Tasso M, Mertz D

Nanoscale. 2025 11 27;:

A Modular Supramolecular Peptide Platform Reveals Atomic-Number-Dependent Mechanisms Driving Radioenhancement.

Jung S, Navarro PL, Barbé E, Gasser A, Bou-Gharios J, Donzeau M, Mirjolet C, Noel G, Schmitt JL, Pivot X, Harlepp S, Detappe A

ACS Nano. 2025 11 19;:

Inverse Correlation between Endoplasmic Reticulum Stress Intensity and Antitumor Immune Response with Ruthenium(II)-Based Photosensitizers for the Photodynamic Therapy of Head and Neck Squamous Cell Carcinoma.

Thibaudeau C, Bour C, Scarpi-Luttenauer M, Mesdom P, Karges J, Gandioso A, Zhou L, Harlepp S, Detappe A, Burgy M, Martin S, Mellitzer G, Gaiddon C, Gasser G, Jung AC

J Med Chem. 2025 11 19;:

Nanomaterials Trigger Functional Anti-Tumoral Responses in Primary Human Immune Cells.

Mittelheisser V, Lefebvre O, Banerjee M, Ghosh S, Dupas A, Diringer MC, Blumberger J, Bochler L, Harlepp S, Larnicol A, Pichot A, Stemmelen T, Molitor A, Moritz C, Carapito C, Carapito R, Charbonnière LJ, Lux F, Tillement O, Goetz JG, Detappe A

Adv Sci (Weinh). 2025 07 12;:e05729

Reinforced Polymer-Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab.

Bovone G, Bernhard S, Jacquot G, Mittelheisser V, Mirjolet C, Guzzi EA, Paganella LG, Liebi L, Draussin J, Lopez Navarro P, Barbé E, Lefebvre O, Goetz JG, Charbonnière LJ, Pivot X, Harlepp S, Tibbitt MW, Detappe A

Adv Healthc Mater. 2025 06 9;:e2404660

Spacer engineering in nanoparticle-peptide conjugates boosts targeting specificity for tumor-associated antigens.

Ramírez MLA, Bou-Gharios J, Freis B, Draussin J, Cheignon C, Charbonnière LJ, Laurent S, Gevart T, Gasser A, Jung S, Rossetti F, Tillement O, Noel G, Pivot X, Detappe A, Bégin-Colin S, Harlepp S

Nanoscale. 2025 02 4;:

Defects or no defects? Or how to design 20-25 nm spherical iron oxide nanoparticles to harness both magnetic hyperthermia and photothermia.

Freis B, Kiefer C, Ramirez MLA, Harlepp S, Mertz D, Pichon B, Iacovita C, Laurent S, Begin S

Nanoscale. 2024 10 18;:

Landscape of Subcutaneous Administration Strategies for Monoclonal Antibodies in Oncology.

Jacquot G, Lopez Navarro P, Grange C, Boudali L, Harlepp S, Pivot X, Detappe A

Adv Mater. 2024 08 20;:e2406604

Supramolecular Heterodimer Peptides Assembly for Nanoparticles Functionalization.

Mathieu C, Ghosh S, Draussin J, Gasser A, Jacquot G, Banerjee M, Gupta T, Schmutz M, Mirjolet C, Tillement O, Lux F, Klymchenko A, Donzeau M, Pivot X, Harlepp S, Detappe A

Adv Healthc Mater. 2024 03 5;:e2304250

Subcutaneous Administration of a Zwitterionic Chitosan-Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies.

Gréa T, Jacquot G, Durand A, Mathieu C, Gasser A, Zhu C, Banerjee M, Hucteau E, Mallard J, Lopez Navarro P, Popescu BV, Thomas E, Kryza D, Sidi-Boumedine J, Ferrauto G, Gianolio E, Fleith G, Combet J, Brun S, Erb S, Cianferani S, Charbonnière LJ, Fellmann L, Mirjolet C, David L, Tillement O, Lux F, Harlepp S, Pivot X, Detappe A

Adv Mater. 2023 12 17;:e2308738

Effect of the Size and Shape of Dendronized Iron Oxide Nanoparticles Bearing a Targeting Ligand on MRI, Magnetic Hyperthermia, and Photothermia Properties-From Suspension to In Vitro Studies.

Freis B, Ramirez MLA, Kiefer C, Harlepp S, Iacovita C, Henoumont C, Affolter-Zbaraszczuk C, Meyer F, Mertz D, Boos A, Tasso M, Furgiuele S, Journe F, Saussez S, Bégin-Colin S, Laurent S

Pharmaceutics. 2023 03 30;15(4):

3D single cell migration driven by temporal correlation between oscillating force dipoles.

Godeau AL, Leoni M, Comelles J, Guyomar T, Lieb M, Delanoë-Ayari H, Ott A, Harlepp S, Sens P, Riveline D

Elife. 2022 07 28;11:

Core-shell iron oxide@stellate mesoporous silica for combined nearinfrared photothermia and drug delivery: influence of pH and surface chemistry

Adam A, Harlepp S, Ghilini F, Cotin G, Freis B, Goetz J, Begin-Colin S, Tasso M, Mertz D

Colloids Surf. A: Physicochem. Eng. Asp.. 2022 ;640:128407

Probing Intravascular Adhesion and Extravasation of Tumor Cells with Microfluidics.

Osmani N, Follain G, Gensbittel V, García-León MJ, Harlepp S, Goetz JG

Methods Mol Biol. 2021 ;2294:111-132

Mechanical Adaptability of Tumor Cells in Metastasis.

Gensbittel V, Kräter M, Harlepp S, Busnelli I, Guck J, Goetz JG

Dev Cell. 2020 Nov 3;:

[Influence of fluid mechanics on metastasis formation].

Follain G, Gensbittel V, Mary B, Lefebvre O, Harlepp S, Hyenne V, Goetz JG

Med Sci (Paris). 2020 Oct;36(10):872-878

Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications

Mertz D, Harlepp S, Goetz JG, Bégin D, Schlatter G, Bégin‐Colin S, Hébraud A

. 2020 ;3(2):1900143

Near Infra-Red Light Responsive Carbon Nanotubes@Mesoporous Silica for Photothermia and Drug Delivery to Cancer Cells

Li B, Harlepp S, Gensbittel V, Wells CJR, Bringel O, Goetz JG, Begin-Colin S, Tasso M, Begin D, Mertz D

. 2020 ;17:100308

Fluids and their mechanics in tumour transit: shaping metastasis.

Follain G, Herrmann D, Harlepp S, Hyenne V, Osmani N, Warren SC, Timpson P, Goetz JG

Nat. Rev. Cancer. 2019 Nov 28;:

Metastatic Tumor Cells Exploit Their Adhesion Repertoire to Counteract Shear Forces during Intravascular Arrest.

Osmani N, Follain G, García León MJ, Lefebvre O, Busnelli I, Larnicol A, Harlepp S, Goetz JG

Cell Rep. 2019 Sep 3;28(10):2491-2500.e5

-Heterocyclic Carbene-Platinum Complexes Featuring an Anthracenyl Moiety: Anti-Cancer Activity and DNA Interaction.

Harlepp S, Chardon E, Bouché M, Dahm G, Maaloum M, Bellemin-Laponnaz S

Int J Mol Sci. 2019 Aug 27;20(17):

Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo.

Hyenne V, Ghoroghi S, Collot M, Bons J, Follain G, Harlepp S, Mary B, Bauer J, Mercier L, Busnelli I, Lefebvre O, Fekonja N, Garcia-Leon MJ, Machado P, Delalande F, López AA, Silva SG, Verweij FJ, van Niel G, Djouad F, Peinado H, Carapito C, Klymchenko AS, Goetz JG

Dev. Cell. 2019 Feb 4;:

Wrapped stellate silica nanocomposites as biocompatible luminescent nanoplatforms assessed in vivo.

Perton F, Harlepp S, Follain G, Parkhomenko K, Goetz JG, Bégin-Colin S, Mertz D

J Colloid Interface Sci. 2019 Jan 23;542:469-482

Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells.

Follain G, Osmani N, Azevedo AS, Allio G, Mercier L, Karreman MA, Solecki G, Garcia Leòn MJ, Lefebvre O, Fekonja N, Hille C, Chabannes V, Dollé G, Metivet T, Hovsepian F, Prudhomme C, Pichot A, Paul N, Carapito R, Bahram S, Ruthensteiner B, Kemmling A, Siemonsen S, Schneider T, Fiehler J, Glatzel M, Winkler F, Schwab Y, Pantel K, Harlepp S, Goetz JG

Dev. Cell. 2018 Apr 9;45(1):33-52.e12