Dr LEROUX Agnès

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK-positive metastatic non-small cell lung cancer: A case report.

Simon A, Treffel G, Pax G, Gauchotte G, Husson M, Hanriot I, Leroux A, Merlin JL, Harlé A, Gilson P

Oncol Lett. 2026 10;32(4):448

Intraoperative Ex Vivo Confocal Microscopy for Surgical Margin Assessment in Squamous Cell and Basal Cell Carcinoma (HISTOBLOC): Protocol for a Prospective Monocentric Pilot Study.

Gravante G, Leroux A, Garbar C, Henry L, Cortese S, Beulque E, Mastronicola R, Dolivet G

JMIR Res Protoc. 2026 09 9;15:e91436

Myxoid neoplasms with MAP3K kinase fusion: a study of 39 cases.

Macagno N, Frankel D, Meurgey A, Pissaloux D, Buisson A, Baltrès A, Gouin F, Vaz G, Brahmi M, Dufresne A, Decouvelaere AV, Maran-Gonzales A, Rochaix P, Leroux A, Weinbreck N, de la Fouchardière A, Blay JY, Tirode F, Karanian M

Histopathology. 2026 07 5;:

Local relapse patterns after preoperative radiotherapy of limb and trunk wall soft tissue sarcomas: Prognostic role of imaging and pathologic response factors.

Cuenin M, Levy A, Peiffert D, Sunyach MP, Ducassou A, Cordoba A, Gillon P, Thibouw D, Lapeyre M, Lerouge D, Helfre S, Leroux A, Salleron J, Sirveaux F, Marchal F, P Teixeira,Debordes PA, G Vogin

Clin Transl Radiat Oncol. 2024 09;48:100825

Investigating the prognostic impact of NY-ESO-1 expression and HLA subtypes in metastatic synovial sarcoma.

Dufresne A, Pokras S, Meurgey A, Chabaud S, Toulmonde M, Bompas E, Le Cesne A, Robin YM, Duffaud F, Valentin T, El Zein S, Leroux A, Dubray-Longeras P, Firmin N, de Pinieux G, Noal S, Delfour C, Bollard J, Tonon L, Biette A, Gadot N, Attignon V, Jean-Denis M, Woessner M, Klohe E, Thayaparan T, Eleftheriadou I, Blouch K, Nathenson MJ, Blay JY

ESMO Open. 2024 08 16;9(8):103645

Impact of Positive Resection Margins on Recurrence and Survival Following Resection and Adjuvant Chemotherapy in Pancreatic Cancer: Results of the PRODIGE 24-CCTG PA-6 Randomized Controlled Trial.

Lambert A, Salleron J, Harlé A, Biagi JJ, Leroux A, Thomas J, Monard L, Cros J, Marchal F, Ayav A, Conroy T

Ann Surg. 2024 07 23;:

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy to Treat Pseudomyxoma Peritonei of Ovarian Origin: A Retrospective French RENAPE Group Study.

Trecourt A, Bakrin N, Glehen O, Gertych W, Villeneuve L, Isaac S, Benzerdjeb N, Fontaine J, Genestie C, Dartigues P, Leroux A, Quenet F, Marchal F, Odin C, Khellaf L, Svrcek M, Thierry S, Augros M, Omar A, Devouassoux-Shisheboran M, Kepenekian V,

Ann Surg Oncol. 2024 02 10;:

ASO Visual Abstract: Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy to Treat Pseudomyxoma Peritonei of Ovarian Origin: A Retrospective French RENAPE Group Study.

Trecourt A, Bakrin N, Glehen O, Gertych W, Villeneuve L, Isaac S, Benzerdjeb N, Fontaine J, Genestie C, Dartigues P, Leroux A, Quenet F, Marchal F, Odin C, Khellaf L, Svrcek M, Thierry S, Augros M, Omar A, Devouassoux-Shisheboran M, Kepenekian V,

Ann Surg Oncol. 2024 02 9;:

Improved nationwide survival of sarcoma patients with a network of reference centers.

Blay JY, Penel N, Valentin T, Anract P, Duffaud F, Dufresne A, Verret B, Cordoba A, Italiano A, Brahmi M, Henon C, Amouyel T, Ray-Coquard I, Ferron G, Boudou-Rouquette P, Tlemsani C, Salas S, Rochwerger R, Faron M, Bompas E, Ducassou A, Gangloff D, Gouin F, Firmin N, Piperno-Neumann S, Rios M, Ropars M, Kurtz JE, Le Nail LR, Bertucci F, Carrere S, Llacer C, Watson S, Bonvalot S, Leroux A, Perrin C, Gantzer J, Pracht M, Narciso B, Monneur A, Lebbe C, Hervieu A, Saada-Bouzid E, Dubray-Longeras P, Fiorenza F, Chaigneau L, Nevieres ZM, Soibinet P, Bouché O, Guillemet C, Spano JP, Ruzic JC, Isambert N, Vaz G, Meeus P, Karanian M, Ngo C, Coindre JM, De Pinieux G, Le Loarer F, Ducimetiere F, Chemin C, Morelle M, Toulmonde M, Le Cesne A

Ann Oncol. 2024 01 19;:

Integrated Molecular Characterization of HER2-Low Breast Cancer Using Next Generation Sequencing (NGS).

Merlin JL, Husson M, Sahki N, Gilson P, Massard V, Harlé A, Leroux A

Biomedicines. 2023 11 28;11(12):

[Diagnosis of uterine sarcomas and rare uterine mesenchymal tumours with malignant potential. Guidelines of the French Sarcoma Group and Rare Gynaecological Tumours].

Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Le Frere Belda MA, Averous G, Leroux A, Bataillon G, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C

Bull Cancer. 2023 10 6;:

Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group.

Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C

Gynecol Oncol. 2022 09 13;:

Potential histological discordance revealed by second review in the national rare gynecological cancer network (TMRG).

Henno S, Jeanne C, Rouge TM, Genestie C, Treilleux I, Croce S, Just PA, Le Frere-Belda MA, Guinaudeau E, Penault-Llorca F, Arnould L, Mery-Lamarche E, Leroux A, Lemaire AS, Averous G, Renaud O, Charafe-Jauffret E, Bonneau C, Leaha C, Ray-Coquard I, Devouassoux-Shisheboran M

Gynecol Oncol. 2022 Apr 4;:

Intraoperative prediction of non-sentinel lymph node metastases in breast cancer using cytokeratin 19 mRNA copy number: A retrospective analysis.

Pina H, Salleron J, Gilson P, Husson M, Rouyer M, Leroux A, Rauch P, Marchal F, Käppeli M, Merlin JL, Harlé A

Mol Clin Oncol. 2022 Mar;16(3):58

Antitumor Effect and Induced Immune Response Following Exposure of Hexaminolevulinate and Blue Light in Combination with Checkpoint Inhibitor in an Orthotopic Model of Rat Bladder Cancer.

Lamy L, Thomas J, Leroux A, Bisson JF, Myren K, Godal A, Stensrud G, Bezdetnaya L

Biomedicines. 2022 Feb 25;10(3):

A phase II randomised study of preoperative trastuzumab alone or combined with everolimus in patients with early HER2-positive breast cancer and predictive biomarkers (RADHER trial).

Campone M, Bachelot T, Treilleux I, Pistilli B, Salleron J, Seegers V, Arnedos M, Loussouarn D, Wang Q, Vanlemmens L, Jimenez M, Rios M, Diéras V, Leroux A, Paintaud G, Rezai K, André F, Lion M, Merlin JL

Eur J Cancer. 2021 Oct 19;158:169-180

[2021 update of the GEFPICS' recommendations for HER2 status assessment in invasive breast cancer in France].

Franchet C, Djerroudi L, Maran-Gonzalez A, Abramovici O, Antoine M, Becette V, Berghian A, Blanc-Fournier C, Brabencova E, Charafe-Jauffret E, Chenard MP, Dauplat MM, Delrée P, Duprez-Paumier R, Fleury C, Ghnassia JP, Haudebourg J, Leroux A, MacGrogan G, Mathieu MC, Michenet P, Penault-Llorca F, Poulet B, Robin YM, Roger P, Russ E, Tixier L, Treilleux I, Valent A, Verriele V, Vincent-Salomon A, Arnould L, Lacroix-Triki M,

Ann Pathol. 2021 Aug 12;:

A NGS-based Blood Test for the Diagnosis of Invasive HPV-associated Carcinomas with Extensive Viral Genomic Characterization.

Sastre-Garau X, Diop M, Martin F, Dolivet G, Marchal F, Charra-Brunaud C, Peiffert D, Leufflen L, Dembele B, Demange J, Tosti P, Thomas J, Leroux A, Merlin JL, Diop-Ndiaye H, Costa JM, Salleron J, Harle A

Clin Cancer Res. 2021 Jun 9;:

Phenotypic discordance between primary and metastatic breast cancer in the large-scale real-life multicenter French ESME cohort.

Grinda T, Joyon N, Lusque A, Lefèvre S, Arnould L, Penault-Llorca F, Macgrogan G, Treilleux I, Vincent-Salomon A, Haudebourg J, Maran-Gonzalez A, Charafe-Jauffret E, Courtinard C, Franchet C, Verriele V, Brain E, Tas P, Blanc-Fournier C, Leroux A, Loussouarn D, Berghian A, Brabencova E, Ghnassia JP, Scoazec JY, Delaloge S, Filleron T, Lacroix-Triki M

NPJ Breast Cancer. 2021 Apr 16;7(1):41

Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network.

de Pinieux G, Karanian M, Le Loarer F, Le Guellec S, Chabaud S, Terrier P, Bouvier C, Batistella M, Neuville A, Robin YM, Emile JF, Moreau A, Larousserie F, Leroux A, Stock N, Lae M, Collin F, Weinbreck N, Aubert S, Mishellany F, Charon-Barra C, Croce S, Doucet L, Quintin-Rouet I, Chateau MC, Bazille C, Valo I, Chetaille B, Ortonne N, Brouchet A, Rochaix P, Demuret A, Ghnassia JP, Mescam L, Macagno N, Birtwisle-Peyrottes I, Delfour C, Angot E, Pommepuy I, Ranchere D, Chemin-Airiau C, Jean-Denis M, Fayet Y, Courrèges JB, Mesli N, Berchoud J, Toulmonde M, Italiano A, Le Cesne A, Penel N, Ducimetiere F, Gouin F, Coindre JM, Blay JY,

PLoS One. 2021 ;16(2):e0246958

Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers.

Gilson P, Levy J, Rouyer M, Demange J, Husson M, Bonnet C, Salleron J, Leroux A, Merlin JL, Harlé A

. 2020 Oct 2;10(1):16386

Treatment algorithm and prognostic factors for patients with stage I-III carcinoma of the anal canal: a 20-year multicenter study.

Bruyere D, Monnien F, Colpart P, Roncarati P, Vuitton L, Hendrick E, Lepinoy A, Luquain A, Pilard C, Lerho T, Molimard C, Maingon P, Arnould L, Bone-Lepinoy MC, Dusserre L, Martin L, Reynders C, Ancion M, Peiffert D, Leroux A, Hubert P, Delhorme JB, Ghnassia JP, Woronoff AS, Delvenne P, Prétet JL, Bosset JF, Peulen O, Mougin C, Valmary-Degano S, Herfs M

Mod. Pathol.. 2020 Jul 29;:

ICG-induced NIR fluorescence mapping in patients with head & neck tumors after the previous radiotherapy.

Cortese S, Kerrien E, Yakavets I, Meilender R, Mastronicola R, Renard S, Leroux A, Bezdetnaya L, Dolivet G

Photodiagnosis Photodyn Ther. 2020 May 29;:101838

Identification of Specific Tumor Markers in Vulvar Carcinoma Through Extensive Human Papillomavirus DNA Characterization Using Next Generation Sequencing Method.

Thomas J, Leufflen L, Chesnais V, Diry S, Demange J, Depardieu C, Bani MA, Marchal F, Charra-Brunaud C, Merlin JL, Leroux A, Sastre-Garau X, Harlé A

J Low Genit Tract Dis. 2020 Jan;24(1):53-60

Rapid fully-automated assay for routine molecular diagnosis of mutations for personalized therapy of low grade gliomas.

Merlin MS, Gilson P, Rouyer M, Chastagner P, Doz F, Varlet P, Leroux A, Gauchotte G, Merlin JL

Pediatr Hematol Oncol. 2019 Oct 23;:1-12

[Evaluation of the management and conformity to clinical practice guidelines of soft tissues lesions. Study performed at the competence center of Lorraine area].

Genet J, Salleron J, Leroux A, Verhaeghe JL, Simon E

Ann Chir Plast Esthet. 2019 Aug;64(4):326-333

Genomic and transcriptomic comparison of post-radiation versus sporadic sarcomas.

Lesluyes T, Baud J, Pérot G, Charon-Barra C, You A, Valo I, Bazille C, Mishellany F, Leroux A, Renard-Oldrini S, Terrier P, Le Cesne A, Laé M, Piperno-Neumann S, Bonvalot S, Neuville A, Collin F, Maingon P, Coindre JM, Chibon F

Mod. Pathol.. 2019 Jun 26;:

Dual Epigenetic Regulation of ERα36 Expression in Breast Cancer Cells.

Thiebaut C, Chesnel A, Merlin JL, Chesnel M, Leroux A, Harlé A, Dumond H

Int J Mol Sci. 2019 May 29;20(11):

Uncommon mutational profiles of metastatic colorectal cancer detected during routine genotyping using next generation sequencing.

Franczak C, Kandathil SM, Gilson P, Husson M, Rouyer M, Demange J, Leroux A, Merlin JL, Harlé A

Sci Rep. 2019 May 8;9(1):7083

HPV insertional pattern as a personalized tumor marker for the optimized tumor diagnosis and follow-up of patients with HPV-associated carcinomas: a case report.

Harlé A, Guillet J, Thomas J, Demange J, Dolivet G, Peiffert D, Leroux A, Sastre-Garau X

BMC Cancer. 2019 Mar 28;19(1):277

Evaluation of KRAS, NRAS and BRAF hotspot mutations detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated platform and Next-Generation Sequencing for laboratory workflow optimisation.

Gilson P, Franczak C, Dubouis L, Husson M, Rouyer M, Demange J, Perceau M, Leroux A, Merlin JL, Harlé A

PLoS ONE. 2019 ;14(7):e0219204

Integrated routine workflow using next-generation sequencing and a fully-automated platform for the detection of KRAS, NRAS and BRAF mutations in formalin-fixed paraffin embedded samples with poor DNA quality in patients with colorectal carcinoma.

Franczak C, Dubouis L, Gilson P, Husson M, Rouyer M, Demange J, Leroux A, Merlin JL, Harlé A

PLoS ONE. 2019 ;14(2):e0212801

Comparison of Three Real-Time PCR Assays for the Detection of PIK3CA Somatic Mutations in Formalin-Fixed Paraffin Embedded Tissues of Patients with Breast Carcinomas.

Lambert A, Salleron J, Lion M, Rouyer M, Lozano N, Leroux A, Merlin JL, Harlé A

Pathol. Oncol. Res.. 2018 Nov 13;:

Localized Myxofibrosarcomas: Roles of Surgical Margins and Adjuvant Radiation Therapy.

Boughzala-Bennadji R, Stoeckle E, Le Péchoux C, Méeus P, Honoré C, Attal J, Duffaud F, De Pinieux G, Bompas E, Thariat J, Leroux A, Bertucci F, Isambert N, Delcambre C, Blay JY, Sunyach MP, Coindre JM, Sargos P, Penel N, Bonvalot S

Int. J. Radiat. Oncol. Biol. Phys.. 2018 Oct 1;102(2):399-406

Accelerated mutation analysis using a fully automated PCR platform improves the management of patients with metastatic melanoma.

Serre D, Salleron J, Husson M, Leroux A, Gilson P, Merlin JL, Geoffrois L, Harlé A

Oncotarget. 2018 Aug 14;9(63):32232-32237

Evaluation and validation of HPV real-time PCR assay for the detection of HPV DNA in oral cytobrush and FFPE samples.

Harlé A, Guillet J, Thomas J, Sastre-Garau X, Rouyer M, Ramacci C, Gilson P, Dubois C, Dolivet G, Leroux A, Salleron J, Merlin JL

Sci Rep. 2018 Jul 27;8(1):11313

Minichromosome maintenance complex component 6 (MCM6) expression correlates with histological grade and survival in endometrioid endometrial adenocarcinoma.

Hotton J, Agopiantz M, Leroux A, Charra-Brunaud C, Marie B, Busby-Venner H, Morel O, Guéant JL, Vignaud JM, Battaglia-Hsu SF, Gauchotte G

Virchows Arch.. 2018 Apr;472(4):623-633

Genome profiling is an efficient tool to avoid the STUMP classification of uterine smooth muscle lesions: a comprehensive array-genomic hybridization analysis of 77 tumors.

Croce S, Ducoulombier A, Ribeiro A, Lesluyes T, Noel JC, Amant F, Guillou L, Stoeckle E, Devouassoux-Shisheboran M, Penel N, Floquet A, Arnould L, Guyon F, Mishellany F, Chakiba C, Cuppens T, Zikan M, Leroux A, Frouin E, Farre I, Genestie C, Valo I, MacGrogan G, Chibon F

Mod. Pathol.. 2018 Jan 12;:

Tumor lymphocyte immune response to preoperative radiotherapy in locally advanced rectal cancer: The LYMPHOREC study.

Mirjolet C, Charon-Barra C, Ladoire S, Arbez-Gindre F, Bertaut A, Ghiringhelli F, Leroux A, Peiffert D, Borg C, Bosset JF, Créhange G

Oncoimmunology. 2018 ;7(3):e1396402

Comparison of Five Different Assays for the Detection of BRAF Mutations in Formalin-Fixed Paraffin Embedded Tissues of Patients with Metastatic Melanoma.

Franczak C, Salleron J, Dubois C, Filhine-Trésarrieu P, Leroux A, Merlin JL, Harlé A

Mol Diagn Ther. 2017 Apr;21(2):209-216

PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas.

Bertucci F, Finetti P, Perrot D, Leroux A, Collin F, Le Cesne A, Coindre JM, Blay JY, Birnbaum D, Mamessier E

Oncoimmunology. 2017 ;6(3):e1278100

[About a presacral myelolipoma].

Oldrini G, Bron G, Renard-Oldrini S, Leroux A, Grignon B, Henrot P

Presse Med. 2016 Dec;45(12 Pt 1):1194-1196

Comparison of the histopathological results of the radioguided percutaneous microbiopsies and the operative specimens of soft tissue tumors of limbs, trunk and retroperitoneum.

Oldrini G, Leroux A, Vogin G, Rios M, Marchal F, Sirveaux F, Verhaeghe JL, Renard-Oldrini S, Lesanne G, Salleron J, Henrot P

Presse Med. 2016 Nov;45(11):e363-e368

A HELLP syndrome complicates a gestational trophoblastic neoplasia in a perimenopausal woman: a case report.

Vogin G, Golfier F, Hajri T, Leroux A, Weber B

BMC Cancer. 2016 Aug;16:573

Sentinel Node in Oral Cancer: The Nuclear Medicine Aspects. A Survey from the Sentinel European Node Trial.

Tartaglione G, Stoeckli SJ, de Bree R, Schilling C, Flach GB, Bakholdt V, Sorensen JA, Bilde A, von Buchwald C, Lawson G, Dequanter D, Villarreal PM, Forcelledo MF, Amezaga JA, Moreira A, Poli T, Grandi C, Vigili MG, O'Doherty M, Donner D, Bloemena E, Rahimi S, Gurney B, Haerle SK, Broglie MA, Huber GF, Krogdah AL, Sebbesen LR, Odell E, Junquera Gutierrez LM, Barbier L, Santamaria-Zuazua J, Jacome M, Nollevaux MC, Bragantini E, Lothaire P, Silini EM, Sesenna E, Dolivet G, Mastronicola R, Leroux A, Sassoon I, Sloan P, Colletti PM, Rubello D, McGurk M

Clin Nucl Med. 2016 Jul;41(7):534-42

Rare RAS Mutations in Metastatic Colorectal Cancer Detected During Routine RAS Genotyping Using Next Generation Sequencing.

Harlé A, Filhine-Tresarrieu P, Husson M, Boidot R, Rouyer M, Dubois C, Leroux A, Merlin JL

Target Oncol. 2016 Jun;11(3):363-70

Detection of BRAF Mutations Using a Fully Automated Platform and Comparison with High Resolution Melting, Real-Time Allele Specific Amplification, Immunohistochemistry and Next Generation Sequencing Assays, for Patients with Metastatic Melanoma.

Harlé A, Salleron J, Franczak C, Dubois C, Filhine-Tressarieu P, Leroux A, Merlin JL

PLoS ONE. 2016 ;11(4):e0153576

Plasmablastic lymphoma: oral presentation in patient suffering from osteradionecrosis of the jaw.

Kichenbrand C, Egloff C, Guillet J, Delaître B, Bastien C, Leroux A, Dolivet G, Phulpin B

Int J Surg Case Rep. 2016 ;29:94-97

Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer.

Schilling C, Stoeckli SJ, Haerle SK, Broglie MA, Huber GF, Sorensen JA, Bakholdt V, Krogdahl A, von Buchwald C, Bilde A, Sebbesen LR, Odell E, Gurney B, O'Doherty M, de Bree R, Bloemena E, Flach GB, Villarreal PM, Fresno Forcelledo MF, Junquera Gutiérrez LM, Amézaga JA, Barbier L, Santamaría-Zuazua J, Moreira A, Jacome M, Vigili MG, Rahimi S, Tartaglione G, Lawson G, Nollevaux MC, Grandi C, Donner D, Bragantini E, Dequanter D, Lothaire P, Poli T, Silini EM, Sesenna E, Dolivet G, Mastronicola R, Leroux A, Sassoon I, Sloan P, McGurk M

Eur. J. Cancer. 2015 Dec;51(18):2777-84

[Liver biopsy: A cause of little described complication].

Oldrini G, Leroux A, Grignon B, Troufleau P, Boyer B, Renard-Oldrini S, Vogin G, Henrot P

Presse Med. 2015 Sep 7. pii: S0755-4982(15)00351-6

Uterine smooth muscle tumor analysis by comparative genomic hybridization: a useful diagnostic tool in challenging lesions.

Croce S, Ribeiro A, Brulard C, Noel JC, Amant F, Stoeckle E, Devouassoux-Shisheborah M, Floquet A, Arnould L, Guyon F, Mishellany F, Garbay D, Cuppens T, Zikan M, Leroux A, Frouin E, Duvillard P, Terrier P, Farre I, Valo I, MacGrogan GM, Chibon F

Mod Pathol. 2015 May 1

Gene expression profiling of desmoid tumors by cDNA microarrays and correlation with Progression-Free survival.

Salas S, Brulard C, Terrier P, Ranchere-Vince D, Mechine-Neuville A, Guillou L, Lae M, Leroux A, Verola O, Kurtz JE, Bonvalot S, Blay JY, Le Cesne A, Aurias A, Coindre JM, Chibon F

Clin Cancer Res. 2015 Apr 15. pii: clincanres.2910.2014.

[Granulosa cell tumor of the ovary: retrospective study of 17 cases].

Rebstock LE, Leufflen L, Leroux A, Harter V, Verhaeghe JL, Marchal F

Gynecol Obstet Fertil. 2014 May;42(5):331-3

Incidence of occult contralateral carcinomas of the breast following mastoplasty aimed at symmetrization.

Sorin T, Fyad JP, Pujo J, Colson T, Bordes V, Leroux A, Marchal F, Brix M, Simon E, Verhaeghe JL, Classe JM, Dolivet G

Ann Chir Plast Esthet. 2014 Apr;59(2):e21-8

Breast microcalcifications: the lesions in anatomical pathology.

Henrot P, Leroux A, Barlier C, Genin P

Diagn Interv Imaging. 2014 Feb;95(2):141-52

Spectral features selection and classification for bimodal optical spectroscopy applied to bladder cancer in vivo diagnosis.

Pery E, Blondel WC, Tindel S, Ghribi M, Leroux A, Guillemin F

IEEE Trans Biomed Eng. 2014 Jan;61(1):207-16

Expression and activation of P38 MAP kinase in invasive ductal breast cancers: correlation with expression of the estrogen receptor, HER2 and downstream signaling phosphorylated proteins.

Merlin JL, Harle A, Lion M, Ramacci C, Leroux A

Oncol Rep. 2013 Oct;30(4):1943-8

Using one-step nucleic acid amplification (OSNA) for intraoperative detection of lymph node metastasis in breast cancer patients avoids second surgery and accelerates initiation of adjuvant therapy.

Klingler S, Marchal F, Rauch P, Kenouchi O, Chretien AS, Genin P, Leroux A, Merlin JL

Ann Oncol. 2013 Sep;24(9):2305-9

Comparison of COBAS 4800 KRAS, TaqMan PCR and High Resolution Melting PCR assays for the detection of KRAS somatic mutations in formalin-fixed paraffin embedded colorectal carcinomas.

Harle A, Busser B, Rouyer M, Harter V, Genin P, Leroux A, Merlin JL

Virchows Arch. 2013 Mar;462(3):329-35

Optimization of routine KRAS mutation PCR-based testing procedure for rational individualized first-line-targeted therapy selection in metastatic colorectal cancer.

Chretien AS, Harle A, Meyer-Lefebvre M, Rouyer M, Husson M, Ramacci C, Harter V, Genin P, Leroux A, Merlin JL

Cancer Med. 2013 Feb;2(1):11-20

Predictive factors of positive circumferential resection margin after radiochemotherapy for rectal cancer: the French randomised trial ACCORD12/0405 PRODIGE 2.

Rullier A, Gourgou-Bourgade S, Jarlier M, Bibeau F, Chassagne-Clement C, Hennequin C, Tisseau L, Leroux A, Ettore F, Peoc'h M, Diebold MA, Robin YM, Kleinclaus I, Mineur L, Petitjean C, Mosnier JF, Soubeyran I, Padilla N, Lemaistre AI, Berille J, Denis B, Conroy T, Gerard JP

Eur J Cancer. 2013 Jan;49(1):82-9

Implications of a positive sentinel node in oral squamous cell carcinoma.

Gurney BA, Schilling C, Putcha V, Alkureishi LW, Alvarez AJ, Bakholdt V, Barbier Herrero L, Barzan L, Bilde A, Bloemena E, Salces CC, Dalla Palma P, de Bree R, Dequanter D, Dolivet G, Donner D, Flach GB, Fresno M, Grandi C, Haerle S, Huber GF, Hunter K, Lawson G, Leroux A, Lothaire PH, Mamelle G, Silini EM, Mastronicola R, Odell EW, O'Doherty MJ, Poli T, Rahimi S, Ross GL, Zuazua JS, Santini S, Sebbesen L, Shoaib T, Sloan P, Sorensen JA, Soutar DS, Therkildsen MH, Vigili MG, Villarreal PM, von Buchwald C, Werner JA, Wiegand S, McGurk M

Head Neck. 2012 Nov;34(11):1580-5

Abdominal inflammatory myofibroblastic tumour.

Aptel S, Gervaise A, Fairise A, Henrot P, Leroux A, Guillemin F, Laurent V, Regent D

Diagn Interv Imaging. 2012 May;93(5):410-2

Diagnostic performance of one-step nucleic acid amplification for intraoperative sentinel node metastasis detection in breast cancer patients.

Le Frere-Belda MA, Bats AS, Gillaizeau F, Poulet B, Clough KB, Nos C, Peoc'h M, Seffert P, Bouteille C, Leroux A, Guillemin F, Blanc-Fournier C, Crouet H, Arnould L, Cuisenier J, Penault-Llorca F, Gimbergues P, Jacquemier J, Houvenaeghel G, Chatellier G, Lecuru F

Int J Cancer. 2012 May 15;130(10):2377-86

[Surgery and postoperative radiation therapy in primary retroperitoneal sarcomas: experience of the cancer centre Alexis-Vautrin].

Fuks D, Verhaeghe JL, Marchal F, Guillemin F, Beckendorf V, Peiffert D, Leroux A, Rios M, Troufleau P, Marchal C

Cancer Radiother. 2012 May;16(3):194-200

Experimental model of naturally occurring post-radiation sarcoma: interest of positron emission tomography (PET) for early detection.

Phulpin B, Tran N, Leroux A, Poussier S, Marie PY, Pinel S, Huger S, Henrot P, Gallet P, Blaise C, Bravetti P, Graff P, Merlin JL, Dolivet G

J Radiat Res. 2012;53(1):101-9.

Sentinel lymph node biopsy in patients with conjunctival and eyelid cancers: experience in 17 patients.

Maalouf TJ, Dolivet G, Angioi KS, Leroux A, Genin P, George JL

Ophthal Plast Reconstr Surg. 2012 Jan;28(1):30-4.

Visualisation of sentinel lymph node with indium-based near infrared emitting Quantum Dots in a murine metastatic breast cancer model.

Helle M, Cassette E, Bezdetnaya L, Pons T, Leroux A, Plenat F, Guillemin F, Dubertret B, Marchal F

PLoS One. 2012;7(8):e44433

[Imaging follow-up of soft tissue sarcomas].

Oldrini G, Renard-Oldrini S, Leroux A, Rios M, Verhaeghe JL, Boyer B, Troufleau P, Henrot P

J Radiol. 2011 Oct;92(10):915-9

Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis.

Gisquet H, Liu H, Blondel WC, Leroux A, Latarche C, Merlin JL, Chassagne JF, Peiffert D, Guillemin F

Skin Res Technol. 2011 May;17(2):160-6

[Metaplastic carcinomas of the breast: a morphological and immunohistochemical study].

Gauchotte G, Gauchotte E, Bressenot A, Verhaeghe JL, Guillemin F, Leroux A, Genin P

Ann Pathol. 2011 Feb;31(1):18-27

Long-term alterations of cytokines and growth factors expression in irradiated tissues and relation with histological severity scoring.

Gallet P, Phulpin B, Merlin JL, Leroux A, Bravetti P, Mecellem H, Tran N, Dolivet G

PLoS One. 2011;6(12):e29399

Fluorescence imaging and whole-body biodistribution of near-infrared-emitting quantum dots after subcutaneous injection for regional lymph node mapping in mice.

Pic E, Pons T, Bezdetnaya L, Leroux A, Guillemin F, Dubertret B, Marchal F

Mol Imaging Biol. 2010 Aug;12(4):394-405

Re-assessment of chronic radio-induced tissue damage in a rat hindlimb model.

Phulpin B, Dolivet G, Marie PY, Poussier S, Gallet P, Leroux A, Graff P, Groubach F, Bravetti P, Merlin JL, Tran N

Exp Ther Med. 2010 Jul;1(4):553-560

Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity.

Chibon F, Lagarde P, Salas S, Perot G, Brouste V, Tirode F, Lucchesi C, de Reynies A, Kauffmann A, Bui B, Terrier P, Bonvalot S, Le Cesne A, Vince-Ranchere D, Blay JY, Collin F, Guillou L, Leroux A, Coindre JM, Aurias A

Nat Med. 2010 Jul;16(7):781-7

Molecular characterization by array comparative genomic hybridization and DNA sequencing of 194 desmoid tumors.

Salas S, Chibon F, Noguchi T, Terrier P, Ranchere-Vince D, Lagarde P, Benard J, Forget S, Blanchard C, Domont J, Bonvalot S, Guillou L, Leroux A, Mechine-Neuville A, Schoffski P, Lae M, Collin F, Verola O, Carbonnelle A, Vescovo L, Bui B, Brouste V, Sobol H, Aurias A, Coindre JM

Genes Chromosomes Cancer. 2010 Jun;49(6):560-8.

Clinical and biological significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas.

Italiano A, Bianchini L, Gjernes E, Keslair F, Ranchere-Vince D, Dumollard JM, Haudebourg J, Leroux A, Mainguene C, Terrier P, Chibon F, Coindre JM, Pedeutour F

Clin Cancer Res. 2009 Sep 15;15(18):5696-703

Bimodal spectroscopic evaluation of ultra violet-irradiated mouse skin inflammatory and precancerous stages: instrumentation, spectral feature extraction/selection and classification (k-NN, LDA and SVM).

Diaz-Ayil G, Amouroux M, Blondel WCPM, Bourg-Heckly G, Leroux A, Guillemin F, Granjon Y

Eur Phys J-appl Phys. 2009 Jul;47(1):12707.

Validation of a phosphoprotein array assay for characterization of human tyrosine kinase receptor downstream signaling in breast cancer.

Chergui F, Chretien AS, Bouali S, Ramacci C, Rouyer M, Bastogne T, Genin P, Leroux A, Merlin JL

Clin Chem. 2009 Jul;55(7):1327-36

Soft tissue sarcomas of the trunk wall (STS-TW): a study of 343 patients from the French Sarcoma Group (FSG) database.

Salas S, Bui B, Stoeckle E, Terrier P, Ranchere-Vince D, Collin F, Leroux A, Guillou L, Michels JJ, Trassard M, Valo I, Robin YM, Marques B, Brouste V, Coindre JM

Ann Oncol. 2009 Jun;20(6):1127-35

Simultaneous characterization of optical and rheological properties of carotid arteries via bimodal spectroscopy: experimental and simulation results.

Pery E, Blondel WC, Didelon J, Leroux A, Guillemin F

IEEE Trans Biomed Eng. 2009 May;56(5):1267-76

Preventing bladder tumor implantation with photodynamic therapy in a rat model mimicking post-fluorescence guided transurethral resection.

Berrahmoune S, Bezdetnaya L, Leroux A, Guillemin F, D'Hallewin MA

J Urol. 2009 Mar;181(3):1381-6

Classification of ultraviolet irradiated mouse skin histological stages by bimodal spectroscopy: multiple excitation autofluorescence and diffuse reflectance.

Amouroux M, Diaz-Ayil G, Blondel WC, Bourg-Heckly G, Leroux A, Guillemin F

J Biomed Opt. 2009 Jan-Feb;14(1):014011.

Photodynamic therapy with intratumoral administration of Lipid-Based mTHPC in a model of breast cancer recurrence.

D'Hallewin MA, Kochetkov D, Viry-Babel Y, Leroux A, Werkmeister E, Dumas D, Grafe S, Zorin V, Guillemin F, Bezdetnaya L

Lasers Surg Med. 2008 Oct;40(8):543-9.

HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon.

Italiano A, Bianchini L, Keslair F, Bonnafous S, Cardot-Leccia N, Coindre JM, Dumollard JM, Hofman P, Leroux A, Mainguene C, Peyrottes I, Ranchere-Vince D, Terrier P, Tran A, Gual P, Pedeutour F

Int J Cancer. 2008 May 15;122(10):2233-41.

Damaged DNA binding protein 2 plays a role in breast cancer cell growth.

Kattan Z, Marchal S, Brunner E, Ramacci C, Leroux A, Merlin JL, Domenjoud L, Dauca M, Becuwe P

PLoS ONE. 2008 Apr 23;3(4):e2002.

Translocation-positive low-grade fibromyxoid sarcoma: Clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma - A study from the French Sarcoma Gr

Guillou L, Benhattar J, Gengler C, Gallagher G, Ranchere-Vince D, Collin F, Terrier P, Terrier-Lacombe MJ, Leroux A, Marques B, Somerhausen NDA, Keslair F, Pedeutour F, Coindre JM

Am J Surg Pathol. 2007 Sep;31(9):1387-402.

Vascular proliferations of the skin after radiation therapy for breast cancer: clinicopathologic analysis of a series in favor of a benign process: a study from the French Sarcoma Group.

Gengler C, Coindre JM, Leroux A, Trassard M, Ranchere-Vince D, Valo I, Michels JJ, Guillou L

Cancer. 2007 Apr 15;109(8):1584-98.

Vaginal metastasis revealing colon adenocarcinoma.

Marchal F, Leroux A, Hoffstetter S, Granger P

Int J Colorectal Dis. 2006 Dec;21(8):861-2

A novel orthotopic bladder tumor model with predictable localization of a solitary tumor.

El Khatib S, Berrahmoune S, Leroux A, Bezdetnaya L, Guillemin F, D'Hallewin MA

Cancer Biol Ther. 2006 Oct;5(10):1327-31

Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization.

Ndoye A, Dolivet G, Hogset A, Leroux A, Fifre A, Erbacher P, Berg K, Behr JP, Guillemin F, Merlin JL

Mol Ther. 2006 Jun;13(6):1156-62

Prevention of biliary lesions that may occur during radiofrequency ablation of the liver: study on the pig.

Marchal F, Elias D, Rauch P, Zarnegar R, Leroux A, Stines J, Verhaeghe JL, Guillemin F, Carteaux JP, Villemot JP

Ann Surg. 2006 Jan;243(1):82-8.

Results of preoperative lymphoscintigraphy for breast cancer are predictive of identification of axillary sentinel lymph nodes.

Marchal F, Rauch P, Morel O, Mayer JC, Olivier P, Leroux A, Verhaeghe JL, Guillemin F

World J Surg. 2006 Jan;30(1):55-62.

Development of an HT29 liver metastases model in nude rats.

Marchal F, Tran N, Marchal S, Leroux A, Marchal C, Bolotine L, Guillemin F, Villemot JP

Oncol. Rep.. 2005 Nov;14(5):1203-7

Endoscopic confocal fluorescence microscopy of normal and tumor bearing rat bladder.

D'Hallewin MA, El Khatib S, Leroux A, Bezdetnaya L, Guillemin F

J. Urol.. 2005 Aug;174(2):736-40

Sustained gene transfer and enhanced cell death following glucosylated-PEI-mediated p53 gene transfer with photochemical internalisation in p53-mutated head and neck carcinoma cells.

Ndoye A, Bouali S, Dolivet G, Leroux A, Erbacher P, Behr JP, Berg K, Guillemin F, Merlin JL

Int. J. Oncol.. 2004 Dec;25(6):1575-81

Enhanced gene transfer and cell death following p53 gene transfer using photochemical internalisation of glucosylated PEI-DNA complexes.

Ndoye A, Merlin JL, Leroux A, Dolivet G, Erbacher P, Behr JP, Berg K, Guillemin F

J Gene Med. 2004 Aug;6(8):884-94

[Preoperative brachytherapy for clinical stage I and II endometrial carcinoma: results from a series of 780 patients with a 10-year follow-up].

Hoffstetter S, Brunaud C, Marchal C, Luporsi E, Guillemin F, Leroux A, Bey P, Peiffert D

Cancer Radiother. 2004 Jun;8(3):178-87

Biliary lesions during radiofrequency ablation in liver. Study on the pig.

Marchal F, Elias D, Rauch P, Leroux A, Stinès J, Verhaeghe JL, Guillemin F, Villemot JP

Eur Surg Res. ;36(2):88-94

[Use of sentinel lymph node technique in cutaneous melanoma: preliminary experience].

Marchal F, Rauch P, Olivier P, Leroux A, Geoffrois L, Dolivet G, Verhaeghe JL, Guillemin F

Bull Cancer. ;91(7-8):621-8

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