Tahri-Joutey M, Hamer I, Tevel V, Raas Q, Gondcaille C, Trompier D, Kebbaj RE, Ménétrier F, Latruffe N, Lizard G, Nasser B, Savary S, Jadot M, Cherkaoui-Malki M, Andreoletti P

Histochem Cell Biol. 2025 04 14;163(1):44

Oxysterols, age-related-diseases and nutritherapy: focus on 7-ketocholesterol and 7β-hydroxycholesterol.

Vejux A, Ghzaiel I, Mackrill JJ, Dias IHK, Rezig L, Ksila M, Zarrouk A, Nury T, Brahmi F, El Midaoui A, Meziane S, Atanasov AG, Hammami S, Latruffe N, Jouanny P, Lizard G

Prostaglandins Other Lipid Mediat. 2025 04 9;:106993

Influence of Mediterranean Diet and Incidence of Global Warming on Food Habits and Plant Growth in Northern Mediterranean Latitudes: Narrative Review.

Latruffe N, Lizard G

Nutrients. 2025 02 14;17(4):

Effects of polyphenols and their metabolites on age-related diseases.

Zhor C, Wafaa L, Ghzaiel I, Kessas K, Zarrouk A, Ksila M, Ghrairi T, Latruffe N, Masmoudi-Kouki O, El Midaoui A, Vervandier-Fasseur D, Hammami M, Lizard G, Vejux A, Kharoubi O

Biochem Pharmacol. 2023 07 4;214:115674

Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle.

Ksila M, Ghzaiel I, Pires V, Ghrairi T, Masmoudi-Kouki O, Latruffe N, Vervandier-Fasseur D, Vejux A, Lizard G

Molecules. 2023 04 3;28(7):

Two Argan Oil Phytosterols, Schottenol and Spinasterol, Attenuate Oxidative Stress and Restore LPS-Dysregulated Peroxisomal Functions in and Wild-Type BV-2 Microglial Cells.

Essadek S, Gondcaille C, Savary S, Samadi M, Vamecq J, Lizard G, Kebbaj RE, Latruffe N, Benani A, Nasser B, Cherkaoui-Malki M, Andreoletti P

Antioxidants (Basel). 2023 01 11;12(1):

Protective Effect of Nopal Cactus () Seed Oil against Short-Term Lipopolysaccharides-Induced Inflammation and Peroxisomal Functions Dysregulation in Mouse Brain and Liver.

Tahri-Joutey M, Saih FE, El Kebbaj R, Gondcaille C, Vamecq J, Latruffe N, Lizard G, Savary S, Nasser B, Cherkaoui-Malki M, Andreoletti P

Int J Mol Sci. 2022 10 6;23(19):

Effects of blueberry polyphenolic extract on vascular remodeling in spontaneously hypertensive rats.

Thandapilly SJ, Louis X, Kalt W, Raj P, Stobart JL, Aloud BM, Vinqvist-Tymchuk M, Yu L, Kaminski J, Latruffe N, Anderson CM, Anderson HD, Netticadan T

J Food Biochem. 2022 09;46(9):e14227

Cytotoxic and Antioxidant Activities of Imine Analogs of Trans-Resveratrol towards Murine Neuronal N2a Cells.

Ksila M, Vejux A, Prost-Camus E, Durand P, Ghzaiel I, Nury T, Duprey D, Meziane S, Masmoudi-Kouki O, Latruffe N, Ghrairi T, Prost M, Lizard G, Vervandier-Fasseur D

Molecules. 2022 07 23;27(15):

Role of Diet and Nutrients in SARS-CoV-2 Infection: Incidence on Oxidative Stress, Inflammatory Status and Viral Production.

Brahmi F, Vejux A, Ghzaiel I, Ksila M, Zarrouk A, Ghrairi T, Essadek S, Mandard S, Leoni V, Poli G, Vervandier-Fasseur D, Kharoubi O, El Midaoui A, Atanasov AG, Meziane S, Latruffe N, Nasser B, Bouhaouala-Zahar B, Masmoudi-Kouki O, Madani K, Boulekbache-Makhlouf L, Lizard G

Nutrients. 2022 05 25;14(11):

Benefits of the Mediterranean Diet-Wine Association: The Role of Ingredients.

Silva P, Latruffe N

Molecules. 2022 02 14;27(4):

Saffron ( L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases.

El Midaoui A, Ghzaiel I, Vervandier-Fasseur D, Ksila M, Zarrouk A, Nury T, Khallouki F, El Hessni A, Ibrahimi SO, Latruffe N, Couture R, Kharoubi O, Brahmi F, Hammami S, Masmoudi-Kouki O, Hammami M, Ghrairi T, Vejux A, Lizard G

Nutrients. 2022 Jan 29;14(3):

Profiles of Fatty Acids, Polyphenols, Sterols, and Tocopherols and Scavenging Property of Mediterranean Oils: New Sources of Dietary Nutrients for the Prevention of Age-related Diseases.

Rezig L, Martine L, Nury T, Msaada K, Mahfoudhi N, Ghzaiel I, Prost-Camus E, Durand P, Midaoui AE, Acar N, Latruffe N, Vejux A, Lizard G

J Oleo Sci. 2022 ;71(8):1117-1133

Antioxidant Properties and Cytoprotective Effect of L. Seed Oil against 7β-Hydroxycholesterol-Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuation of Cell Death.

Ghzaiel I, Zarrouk A, Nury T, Libergoli M, Florio F, Hammouda S, Ménétrier F, Avoscan L, Yammine A, Samadi M, Latruffe N, Biressi S, Levy D, Bydlowski SP, Hammami S, Vejux A, Hammami M, Lizard G

Antioxidants (Basel). 2021 Nov 5;10(11):

Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα.

Tahri-Joutey M, Andreoletti P, Surapureddi S, Nasser B, Cherkaoui-Malki M, Latruffe N

Int J Mol Sci. 2021 08 20;22(16):

Polyphenols of the Mediterranean Diet and Their Metabolites in the Prevention of Colorectal Cancer.

Yammine A, Namsi A, Vervandier-Fasseur D, Mackrill JJ, Lizard G, Latruffe N

Molecules. 2021 Jun 8;26(12):

Prevention by Dietary Polyphenols (Resveratrol, Quercetin, Apigenin) Against 7-Ketocholesterol-Induced Oxiapoptophagy in Neuronal N2a Cells: Potential Interest for the Treatment of Neurodegenerative and Age-Related Diseases.

Yammine A, Zarrouk A, Nury T, Vejux A, Latruffe N, Vervandier-Fasseur D, Samadi M, Mackrill JJ, Greige-Gerges H, Auezova L, Lizard G

Cells. 2020 Oct 23;9(11):

Wine Consumption and Oral Cavity Cancer: Friend or Foe, Two Faces of Janus.

Silva P, Latruffe N, Gaetano G

Molecules. 2020 05 31;25(11):

Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells.

Yammine A, Nury T, Vejux A, Latruffe N, Vervandier-Fasseur D, Samadi M, Greige-Gerges H, Auezova L, Lizard G

Molecules. 2020 May 13;25(10):

Aza- and Azo-Stilbenes: Bio-Isosteric Analogs of Resveratrol.

Lizard G, Latruffe N, Vervandier-Fasseur D

Molecules. 2020 Jan 30;25(3):

Human Peroxisomal 3-Ketoacyl-CoA Thiolase: Tissue Expression and Metabolic Regulation : Human Peroxisomal Thiolase.

Latruffe N

Adv Exp Med Biol. 2020 ;1299:161-167

The Potential Use of Resveratrol for Cancer Prevention.

Vervandier-Fasseur D, Latruffe N

Molecules. 2019 12 9;24(24):

How efficient is resveratrol as an antioxidant of the Mediterranean diet, towards alterations during the aging process?

Silva P, Sureda A, Tur JA, Andreoletti P, Cherkaoui-Malki M, Latruffe N

Free Radic Res. 2019 10 7;53(sup1):1101-1112

P-Glycoprotein 1 Affects Chemoactivities of Resveratrol against Human Colorectal Cancer Cells.

Aires V, Colin DJ, Doreau A, Di Pietro A, Heydel JM, Artur Y, Latruffe N, Delmas D

Nutrients. 2019 Sep 4;11(9):

Special Issue: Wine and Vine Components and Health.

Latruffe N, Rifler JP

Diseases. 2019 03 19;7(1):

Strategic Syntheses of Vine and Wine Resveratrol Derivatives to Explore their Effects on Cell Functions and Dysfunctions.

Latruffe N, Vervandier-Fasseur D

Diseases. 2018 12 11;6(4):

Induction of Neuronal Differentiation of Murine N2a Cells by Two Polyphenols Present in the Mediterranean Diet Mimicking Neurotrophins Activities: Resveratrol and Apigenin.

Namsi A, Nury T, Hamdouni H, Yammine A, Vejux A, Vervandier-Fasseur D, Latruffe N, Masmoudi-Kouki O, Lizard G

Diseases. 2018 Jul 22;6(3):

Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.

Vamecq J, Andreoletti P, El Kebbaj R, Saih FE, Latruffe N, El Kebbaj MHS, Lizard G, Nasser B, Cherkaoui-Malki M

Oxid Med Cell Longev. 2018 ;2018:6986984

Resveratrol-Induced Changes in MicroRNA Expression in Primary Human Fibroblasts Harboring Carnitine-Palmitoyl Transferase-2 Gene Mutation, Leading to Fatty Acid Oxidation Deficiency.

Aires V, Delmas D, Djouadi F, Bastin J, Cherkaoui-Malki M, Latruffe N

Molecules. 2017 Dec 22;23(1):

Protective Effect of Argan and Olive Oils against LPS-Induced Oxidative Stress and Inflammation in Mice Livers.

El Kamouni S, El Kebbaj R, Andreoletti P, El Ktaibi A, Rharrassi I, Essamadi A, El Kebbaj MS, Mandard S, Latruffe N, Vamecq J, Nasser B, Cherkaoui-Malki M

Int J Mol Sci. 2017 10 19;18(10):

Protective Effect of Cactus Cladode Extracts on Peroxisomal Functions in Microglial BV-2 Cells Activated by Different Lipopolysaccharides.

Saih FE, Andreoletti P, Mandard S, Latruffe N, El Kebbaj MS, Lizard G, Nasser B, Cherkaoui-Malki M

Molecules. 2017 Jan;22(1):

Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages.

Limagne E, Lançon A, Delmas D, Cherkaoui-Malki M, Latruffe N

Nutrients. 2016 May;8(5):

Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation.

Latruffe N, Lancon A, Frazzi R, Aires V, Delmas D, Michaille JJ, Djouadi F, Bastin J, Cherkaoui-Malki M

Ann N Y Acad Sci. 2015 Jul 17

Potential role of oxidative DNA damage in the impact of PNPLA3 variant (rs 738409 C>G) in hepatocellular carcinoma risk.

Limagne E, Cottet V, Cotte AK, Hamza S, Hillon P, Latruffe N, Delmas D

Hepatology. 2014 Sep;60(3):1110-1

Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells.

El Kharrassi Y, Samadi M, Lopez T, Nury T, El Kebbaj R, Andreoletti P, El Hajj HI, Vamecq J, Moustaid K, Latruffe N, El Kebbaj MS, Masson D, Lizard G, Nasser B, Cherkaoui-Malki M

Biochem Biophys Res Commun. 2014 Apr 11;446(3):798-804

Differential protective effects of red wine polyphenol extracts (RWEs) on colon carcinogenesis.

Mazue F, Delmas D, Murillo G, Saleiro D, Limagne E, Latruffe N

Food Funct. 2014 Apr;5(4):663-70

Compared binding properties between resveratrol and other polyphenols to plasmatic albumin: consequences for the health protecting effect of dietary plant microcomponents.

Latruffe N, Menzel M, Delmas D, Buchet R, Lancon A

Molecules. 2014 Oct 24;19(11):17066-77

Inhibition of cancer derived cell lines proliferation by synthesized hydroxylated stilbenes and new ferrocenyl-stilbene analogs. Comparison with resveratrol.

Chalal M, Delmas D, Meunier P, Latruffe N, Vervandier-Fasseur D

Molecules. 2014 Jun 11;19(6):7850-68

Nopal cactus (Opuntia ficus-indica) as a source of bioactive compounds for nutrition, health and disease.

El-Mostafa K, El Kharrassi Y, Badreddine A, Andreoletti P, Vamecq J, El Kebbaj MS, Latruffe N, Lizard G, Nasser B, Cherkaoui-Malki M

Molecules. 2014 Sep 17;19(9):14879-901

Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts.

Aires V, Delmas D, Le Bachelier C, Latruffe N, Schlemmer D, Benoist JF, Djouadi F, Bastin J

Orphanet J Rare Dis. 2014 Jun 5;9:79

The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models.

Colin DJ, Limagne E, Ragot K, Lizard G, Ghiringhelli F, Solary E, Chauffert B, Latruffe N, Delmas D

Cell Death Dis. 2014 Nov 20;5:e1533

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death.

Aires V, Limagne E, Cotte AK, Latruffe N, Ghiringhelli F, Delmas D

Mol Nutr Food Res. 2013 Jul;57(7):1170-81

Resveratrol initiates differentiation of mouse skeletal muscle-derived C2C12 myoblasts.

Kaminski J, Lançon A, Aires V, Limagne E, Tili E, Michaille JJ, Latruffe N

Biochem. Pharmacol.. 2012 Nov 15;84(10):1251-9

Dietary Resveratrol Modulates Metabolic Functions in Skeletal Muscle Cells.

Kaminski J, Lancon A, Tili E, Aires V, Demarquoy J, Lizard G, Michaille JJ I, Latruffe N

. 2012 Apr;20 1:398-401.

A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients.

Rifler JP, Lorcerie F, Durand P, Delmas D, Ragot K, Limagne E, Mazue F, Riedinger JM, d'Athis P, Hudelot B, Prost M, Lizard G, Latruffe N

Mol Nutr Food Res. 2012 Feb;56(2):345-51

Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.

Colin D, Limagne E, Jeanningros S, Jacquel A, Lizard G, Athias A, Gambert P, Hichami A, Latruffe N, Solary E, Delmas D

Cancer Prev Res (Phila). 2011 Jul;4(7):1095-106

Pro-apoptotic versus anti-apoptotic properties of dietary resveratrol on tumoral and normal cardiac cells.

Baarine M, Thandapilly SJ, Louis XL, Mazue F, Yu L, Delmas D, Netticadan T, Lizard G, Latruffe N

Genes Nutr. 2011 May;6(2):161-9

Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe.

Delmas D, Solary E, Latruffe N

Curr Med Chem. 2011;18(8):1100-21.

Transport, stability, and biological activity of resveratrol.

Delmas D, Aires V, Limagne E, Dutartre P, Mazué F, Ghiringhelli F, Latruffe N

Ann. N. Y. Acad. Sci.. 2011 Jan;1215:48-59

Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells.

Tili E, Michaille JJ, Alder H, Volinia S, Delmas D, Latruffe N, Croce CM

Biochem Pharmacol. 2010 Dec 15;80(12):2057-65

Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.

Dugas B, Charbonnier S, Baarine M, Ragot K, Delmas D, Menetrier F, Lherminier J, Malvitte L, Khalfaoui T, Bron A, Creuzot-Garcher C, Latruffe N, Lizard G

Eur J Nutr. 2010 Oct;49(7):435-46