Modified DCF (Docetaxel, Cisplatin and 5-fluorouracil) chemotherapy is effective for the treatment of advanced rectal squamous cell carcinoma.
Fiche publication
Date publication
novembre 2022
Journal
Frontiers in oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BORG Christophe, Dr VIENOT Angélique, Dr KIM Stephano, Dr LAKKIS Zaher, Dr BOUSTANI Jihane
Tous les auteurs :
Hervé L, Kim S, Boustani J, Klajer E, Pernot M, Nguyen T, Lakkis Z, Borg C, Vienot A
Lien Pubmed
Résumé
Advanced rectal squamous cell carcinoma (rSCC) is a very rare and aggressive entity, and the best initial management is crucial for long survival as well as organ preservation and quality of life. Whereas local diseases are treated with chemo-radiotherapy and salvage surgery, data are scarce on how to treat more advanced diseases, and the role of induction chemotherapy is unknown.
Mots clés
DCF, chemoradiotherapy, polychemotherapy, rectal cancer, squamous cell carcinoma
Référence
Front Oncol. 2022 11 17;12:974108