Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.
Fiche publication
Date publication
juillet 2017
Journal
Clinical nutrition (Edinburgh, Scotland)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GUEANT Jean-Louis, Pr QUILLIOT Didier
Tous les auteurs :
Li Z, Gueant-Rodriguez RM, Quilliot D, Sirveaux MA, Meyre D, Gueant JL, Brunaud L
Lien Pubmed
Résumé
Low vitamin B12 and high folate during pregnancy are associated with visceral obesity and insulin resistance in offspring. In the general population, high folate exacerbates the increase of methylmalonic acid, a marker of vitamin B12 deficiency. However, the influence of vitamin B12 and folate and their related markers on insulin resistance and metabolic syndrome remains unknown in severe obesity.
Mots clés
Folates, HOMA-IR, Obesity
Référence
Clin Nutr. 2017 Jul;: