Radiolabeled F(ab')-cetuximab for theranostic purposes in colorectal and skin tumor-bearing mice models.
Fiche publication
Date publication
mai 2018
Journal
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BRUNOTTE François, Pr DENAT Franck, Dr COLLIN Bertrand, Pr COCHET Alexandre, Dr BELLAYE Pierre-Simon
Tous les auteurs :
Bellaye PS, Moreau M, Raguin O, Oudot A, Bernhard C, Vrigneaud JM, Dumont L, Vandroux D, Denat F, Cochet A, Brunotte F, Collin B
Lien Pubmed
Résumé
This study aimed to investigate theranostic strategies in colorectal and skin cancer based on fragments of cetuximab, an anti-EGFR mAb, labeled with radionuclide with imaging and therapeutic properties, In and Lu, respectively.
Mots clés
Cetuximab fragments, Colorectal cancer, EGFR, HSP90, Radioimmunotherapy
Référence
Clin Transl Oncol. 2018 May 17;: