Lu X, Vano YA, Su X, Helleux A, Lindner V, Mouawad R, Spano JP, Rouprêt M, Compérat E, Verkarre V, Sun CM, Bennamoun M, Lang H, Barthelemy P, Cheng W, Xu L, Davidson I, Yan F, Fridman WH, Sautes-Fridman C, Oudard S, Malouf GG

Cell Rep Med. 2023 11 8;:101287

Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability.

Berico P, Nogaret M, Cigrang M, Lallement A, Vand-Rajabpour F, Flores-Yanke A, Gambi G, Davidson G, Seno L, Obid J, Vokshi BH, Le Gras S, Mengus G, Ye T, Cordero CF, Dalmasso M, Compe E, Bertolotto C, Hernando E, Davidson I, Coin F

Cell Rep. 2023 11 2;42(11):113363

Mesenchymal-like tumor cells and myofibroblastic cancer-associated fibroblasts are associated with progression and immunotherapy response of clear-cell renal cell carcinoma.

Davidson G, Helleux A, Vano YA, Lindner V, Fattori A, Cerciat M, Elaidi RT, Verkarre V, Sun CM, Chevreau C, Bennamoun M, Lang H, Tricard T, Fridman WH, Sautes-Fridman C, Su X, Plassard D, Keime C, Thibault-Carpentier C, Barthélémy P, Oudard SM, Davidson I, Malouf GG

Cancer Res. 2023 06 19;:

SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.

Vokshi BH, Davidson G, Tawanaie Pour Sedehi N, Helleux A, Rippinger M, Haller AR, Gantzer J, Thouvenin J, Baltzinger P, Bouarich R, Manriquez V, Zaidi S, Rao P, Msaouel P, Su X, Lang H, Tricard T, Lindner V, Surdez D, Kurtz JE, Bourdeaut F, Tannir NM, Davidson I, Malouf GG

Nat Commun. 2023 05 26;14(1):3034

Getting off to a good start.

Martianov I, Davidson I

Elife. 2023 05 11;12:

Epigenomic mapping identifies an enhancer repertoire that regulates cell identity in bladder cancer through distinct transcription factor networks.

Neyret-Kahn H, Fontugne J, Meng XY, Groeneveld CS, Cabel L, Ye T, Guyon E, Krucker C, Dufour F, Chapeaublanc E, Rapinat A, Jeffery D, Tanguy L, Dixon V, Neuzillet Y, Lebret T, Gentien D, Davidson I, Allory Y, Bernard-Pierrot I, Radvanyi F

Oncogene. 2023 03 22;:

General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.

Säisä-Borreill S, Davidson G, Kleiber T, Thevenot A, Martin E, Mondot S, Blottière H, Helleux A, Mengus G, Plateroti M, Duluc I, Davidson I, Freund JN

Cell Death Differ. 2023 01 13;:

A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.

Roehlen N, Saviano A, El Saghire H, Crouchet E, Nehme Z, Del Zompo F, Jühling F, Oudot MA, Durand SC, Duong FHT, Cherradi S, Gonzalez Motos V, Almeida N, Ponsolles C, Heydmann L, Ostyn T, Lallement A, Pessaux P, Felli E, Cavalli A, Sgrignani J, Thumann C, Koutsopoulos O, Fuchs BC, Hoshida Y, Hofmann M, Vyberg M, Viuff BM, Galsgaard ED, Elson G, Toso A, Meyer M, Iacone R, Schweighoffer T, Teixeira G, Moll S, De Vito C, Roskams T, Davidson I, Heide D, Heikenwälder M, Zeisel MB, Lupberger J, Mailly L, Schuster C, Baumert TF

Sci Transl Med. 2022 12 21;14(676):eabj4221

An enhancer demethylator phenotype converged to immune dysfunction and resistance to immune checkpoint inhibitors in clear-cell renal cell carcinomas.

Lu X, Vano Y, Helleux A, Su X, Lindner V, Davidson G, Mouawad R, Spano JP, Roupret M, Elaidi R, Compérat E, Verkarre V, Sun C, Chevreau C, Bennamoun M, Lang H, Tricard T, Cheng W, Xu L, Davidson I, Yan F, Fridman WH, Sautes-Fridman C, Oudard S, Malouf GG

Clin Cancer Res. 2022 11 14;:

Treatment of HCC with Claudin-1 specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment.

Roehlen N, Muller M, Nehme Z, Crouchet E, Jühling F, Del Zompo F, Cherradi S, Duong FHT, Almeida N, Saviano A, Fernández-Vaquero M, Riedl T, El Saghire H, Durand SC, Ponsolles C, Oudot MA, Martin R, Brignon N, Felli E, Pessaux P, Lallement A, Davidson I, Bandiera S, Thumann C, Marchand P, Moll S, Nicolay B, Bardeesy N, Hoshida Y, Heikenwälder M, Iacone R, Toso A, Meyer M, Elson G, Schweighoffer T, Teixeira G, Zeisel MB, Laquerriere P, Lupberger J, Schuster C, Mailly L, Baumert TF

J Hepatol. 2022 10 26;:

The lncRNA LENOX interacts with RAP2C to regulate metabolism and promote resistance to MAPK inhibition in melanoma.

Gambi G, Mengus G, Davidson G, Demesmaeker E, Cuomo A, Bonaldi T, Katopodi V, Malouf GG, Leucci E, Davidson I

Cancer Res. 2022 10 10;:

Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment.

Yao W, German B, Chraa D, Braud A, Hugel C, Meyer P, Davidson G, Laurette P, Mengus G, Flatter E, Marschall P, Segaud J, Guivarch M, Hener P, Birling MC, Lipsker D, Davidson I, Li M

JCI Insight. 2022 09 15;:

Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors.

Gantzer J, Davidson G, Vokshi B, Weingertner N, Bougoüin A, Moreira M, Lindner V, Lacroix G, Mascaux C, Chenard MP, Bertucci F, Davidson I, Kurtz JE, Sautès-Fridman C, Fridman WH, Malouf GG

Oncologist. 2022 Mar 12;:

Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage.

Colombo S, Petit V, Wagner RY, Champeval D, Yajima I, Gesbert F, Aktary Z, Davidson I, Delmas V, Larue L

Development. 2021 Dec 8;:

Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4.

Kleiber T, Davidson G, Mengus G, Martianov I, Davidson I

Cell Death Dis. 2021 Aug 12;12(8):790

CDK7 and MITF repress a transcription program involved in survival and drug tolerance in melanoma.

Berico P, Cigrang M, Davidson G, Braun C, Sandoz J, Legras S, Vokshi BH, Slovic N, Peyresaubes F, Gene Robles CM, Egly JM, Compe E, Davidson I, Coin F

EMBO Rep. 2021 Jul 23;:e51683

BRN2 is a non-canonical melanoma tumor-suppressor.

Hamm M, Sohier P, Petit V, Raymond JH, Delmas V, Le Coz M, Gesbert F, Kenny C, Aktary Z, Pouteaux M, Rambow F, Sarasin A, Charoenchon N, Bellacosa A, Sanchez-Del-Campo L, Mosteo L, Lauss M, Meijer D, Steingrimsson E, Jönsson GB, Cornell RA, Davidson I, Goding CR, Larue L

Nat Commun. 2021 06 17;12(1):3707

Involvement of Neutrophils in Metastatic Evolution of Pancreatic Neuroendocrine Tumors.

Debien V, Davidson G, Baltzinger P, Kurtz JE, Séverac F, Imperiale A, Pessaux P, Addeo P, Bachellier P, Su X, Davidson I, Chenard MP, Goichot B, Malouf GG

Cancers (Basel). 2021 Jun 2;13(11):

Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation.

Coassolo S, Davidson G, Negroni L, Gambi G, Daujat S, Romier C, Davidson I

Nat Commun. 2021 Mar 19;12(1):1718

Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease.

Pandiani C, Strub T, Nottet N, Cheli Y, Gambi G, Bille K, Husser C, Dalmasso M, Béranger G, Lassalle S, Magnone V, Pédeutour F, Irondelle M, Maschi C, Nahon-Estève S, Martel A, Caujolle JP, Hofman P, LeBrigand K, Davidson I, Baillif S, Barbry P, Ballotti R, Bertolotto C

Cell Death Differ. 2021 Jan 18;:

Comprehensive integrative profiling of upper tract urothelial carcinomas.

Su X, Lu X, Bazai SK, Compérat E, Mouawad R, Yao H, Rouprêt M, Spano JP, Khayat D, Davidson I, Tannir NN, Yan F, Malouf GG

Genome Biol. 2021 Jan 4;22(1):7

Regulation of glycolysis and cancer cell proliferation by PKM2 citrullination.

Coassolo S, Davidson I

Mol Cell Oncol. 2021 ;8(4):1927446

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.

Louphrasitthiphol P, Siddaway R, Loffreda A, Pogenberg V, Friedrichsen H, Schepsky A, Zeng Z, Lu M, Strub T, Freter R, Lisle R, Suer E, Thomas B, Schuster-Böckler B, Filippakopoulos P, Middleton M, Lu X, Patton EE, Davidson I, Lambert JP, Wilmanns M, Steingrímsson E, Mazza D, Goding CR

Mol. Cell. 2020 Jun 4;:

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.

Msaouel P, Malouf GG, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, Shapiro DD, Perelli L, Srinivasan S, Carbone F, Pilié PG, Karki M, Seervai RNH, Vokshi BH, Lopez-Terrada D, Cheng EH, Tang X, Lu W, Wistuba II, Thompson TC, Davidson I, Giuliani V, Schlacher K, Carugo A, Heffernan TP, Sharma P, Karam JA, Wood CG, Walker CL, Genovese G, Tannir NM

Cancer Cell. 2020 Apr 15;:

Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma.

Jühling F, Hamdane N, Crouchet E, Li S, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, Aikata H, Ono A, Tabrizian P, Schwartz M, Polyak SJ, Davidson I, Schmidl C, Bock C, Schuster C, Chayama K, Pessaux P, Tanabe KK, Hoshida Y, Zeisel MB, Duong FH, Fuchs BC, Baumert TF

Gut. 2020 Mar 26;:

[Epigenetic alterations in kidney cancers].

Helleux A, Debien V, Fadloun A, Rippinger M, Lebedinsky S, Davidson I, Malouf GG

Bull Cancer. 2019 Aug 23;:

Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.

Laurette P, Coassolo S, Davidson G, Michel I, Gambi G, Yao W, Sohier P, Li M, Mengus G, Larue L, Davidson I

Cell Death Differ.. 2019 May 7;:

HCV-induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

Hamdane N, Jühling F, Crouchet E, El Saghire H, Thumann C, Oudot MA, Bandiera S, Saviano A, Ponsolles C, Roca Suarez AA, Li S, Fujiwara N, Ono A, Davidson I, Bardeesy N, Schmidl C, Bock C, Schuster C, Lupberger J, Habersetzer F, Doffoël M, Piardi T, Sommacale D, Imamura M, Uchida T, Ohdan H, Aikata H, Chayama K, Boldanova T, Pessaux P, Fuchs BC, Hoshida Y, Zeisel MB, Duong FHT, Baumert TF

Gastroenterology. 2019 Mar 2;:

Dynamic evolution of clonal composition and neoantigen landscape in recurrent metastatic melanoma with a rare combination of driver mutations.

Davidson G, Coassolo S, Kieny A, Ennen M, Pencreach E, Malouf GG, Lipsker D, Davidson I

J. Invest. Dermatol.. 2019 Feb 15;:

Thymine DNA glycosylase as a novel target for melanoma.

Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, Testa JR, Davidson G, Davidson I, Larue L, Sobol RW, Yen TJ, Bellacosa A

Oncogene. 2019 Jan 23;:

Improved Protocol for Chromatin Immunoprecipitation from Mouse Skeletal Muscle.

Joshi S, Ueberschlag-Pitiot V, Metzger D, Davidson I

J Vis Exp. 2017 11 6;(129):

Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.

Bonet C, Luciani F, Ottavi JF, Leclerc J, Jouenne FM, Boncompagni M, Bille K, Hofman V, Bossis G, Marco de Donatis G, Strub T, Cheli Y, Ohanna M, Luciano F, Marchetti S, Rocchi S, Birling MC, Avril MF, Poulalhon N, Luc T, Hofman P, Lacour JP, Davidson I, Bressac-de Paillerets B, Ballotti R, Marine JC, Bertolotto C

J. Natl. Cancer Inst.. 2017 08 1;109(8):

MITF-high and MITF-low cells and a novel subpopulation expressing genes of both cell states contribute to intra and inter-tumoral heterogeneity of primary melanoma.

Ennen M, Keime C, Gambi G, Kieny A, Coassolo S, Thibault-Carpentier C, Margerin-Schaller F, Davidson G, Vagne C, Lipsker D, Davidson I

Clin. Cancer Res.. 2017 Aug;:

Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly.

Tawamie H, Martianov I, Wohlfahrt N, Buchert R, Mengus G, Uebe S, Janiri L, Hirsch FW, Schumacher J, Ferrazzi F, Sticht H, Reis A, Davidson I, Colombo R, Abou Jamra R

Am. J. Hum. Genet.. 2017 Mar;100(3):555-561

Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene.

Chendeb M, Schneider R, Davidson I, Fadloun A

Oncotarget. 2017 Mar;:

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.

Joshi S, Davidson G, Le Gras S, Watanabe S, Braun T, Mengus G, Davidson I

PLoS Genet.. 2017 Feb;13(2):e1006600

Macrophage production and activation are dependent on TRIM33.

Gallouet AS, Ferri F, Petit V, Parcelier A, Lewandowski D, Gault N, Barroca V, Le Gras S, Soler E, Grosveld F, Davidson I, Romeo PH

Oncotarget. 2017 Jan;8(3):5111-5122

TRF2 is recruited to the pre-initiation complex as a testis-specific subunit of TFIIA/ALF to promote haploid cell gene expression.

Martianov I, Velt A, Davidson G, Choukrallah MA, Davidson I

Sci Rep. 2016 Aug;6:32069

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.

Langer D, Martianov I, Alpern D, Rhinn M, Keime C, Dollé P, Mengus G, Davidson I

Nat Commun. 2016 Mar;7:11063

Melanoma addiction to the long non-coding RNA SAMMSON.

Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC

Nature. 2016 Mar;531(7595):518-22

T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy.

Perez-Lloret J, Okoye IS, Guidi R, Kannan Y, Coomes SM, Czieso S, Mengus G, Davidson I, Wilson MS

Proc. Natl. Acad. Sci. U.S.A.. 2016 Feb;113(5):E568-76

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation.

Ferri F, Parcelier A, Petit V, Gallouet AS, Lewandowski D, Dalloz M, van den Heuvel A, Kolovos P, Soler E, Squadrito ML, De Palma M, Davidson I, Rousselet G, Romeo PH

Nat Commun. 2015 Nov;6:8900

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

Koludrovic D, Laurette P, Strub T, Keime C, Le Coz M, Coassolo S, Mengus G, Larue L, Davidson I

PLoS Genet. 2015 Oct 6;11(10):e1005555

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.

Gely-Pernot A, Raverdeau M, Teletin M, Vernet N, Feret B, Klopfenstein M, Dennefeld C, Davidson I, Benoit G, Mark M, Ghyselinck NB

PLoS Genet. 2015 Oct 1;11(10):e1005501

MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma.

Ullrich N, Loffek S, Horn S, Ennen M, Sanchez-Del-Campo L, Zhao F, Breitenbuecher F, Davidson I, Singer BB, Schadendorf D, Goding CR, Helfrich I

Pigment Cell Melanoma Res. 2015 Aug 24

A Brn2-Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells.

Urban S, Kobi D, Ennen M, Langer D, Le Gras S, Ye T, Davidson I

J. Cell. Sci.. 2015 Jul;128(13):2303-18

No evidence for generation of alternatively spliced isoforms from the mutated Trim24 allele lacking exon 4 in mouse liver.

Herquel B, Keime C, Davidson I

J. Hepatol.. 2015 Jul;63(1):276-7

Single-cell gene expression signatures reveal melanoma cell heterogeneity.

Ennen M, Keime C, Kobi D, Mengus G, Lipsker D, Thibault-Carpentier C, Davidson I

Oncogene. 2015 Jun;34(25):3251-63

Neuronal Identity Genes Regulated by Super-Enhancers Are Preferentially Down-Regulated in the Striatum of Huntington's Disease Mice.

Achour M, Le Gras S, Keime C, Parmentier F, Lejeune FX, Boutillier AL, Neri C, Davidson I, Merienne K

Hum Mol Genet. 2015 Mar 17. pii: ddv099.

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.

Laurette P, Strub T, Koludrovic D, Keime C, Le Gras S, Seberg H, Van Otterloo E, Imrichova H, Siddaway R, Aerts S, Cornell RA, Mengus G, Davidson I

Elife. 2015 Mar 24;4

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.

Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, Kohlmeyer J, Renn M, Phung B, Aymans P, Schmidt T, Hornung V, Davidson I, Goding CR, Jonsson G, Landsberg J, Tuting T, Holzel M

Nat Commun. 2015 Nov 4;6:8755

Structural basis of natural promoter recognition by the retinoid X nuclear receptor.

Osz J, McEwen AG, Poussin-Courmontagne P, Moutier E, Birck C, Davidson I, Moras D, Rochel N

Sci Rep. 2015 Feb 3;5:8216

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.

Denecker G, Vandamme N, Akay O, Koludrovic D, Taminau J, Lemeire K, Gheldof A, De Craene B, Van Gele M, Brochez L, Udupi GM, Rafferty M, Balint B, Gallagher WM, Ghanem G, Huylebroeck D, Haigh J, van den Oord J, Larue L, Davidson I, Marine JC, Berx G

Cell Death Differ. 2014 Aug;21(8):1250-61

Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.

Fernandez-Barral A, Orgaz JL, Baquero P, Ali Z, Moreno A, Tiana M, Gomez V, Riveiro-Falkenbach E, Canadas C, Zazo S, Bertolotto C, Davidson I, Rodriguez-Peralto JL, Palmero I, Rojo F, Jensen LD, del Peso L, Jimenez B

Neoplasia. 2014 Jun;16(6):529-42

Phosphorylation of the retinoic acid receptor RARgamma2 is crucial for the neuronal differentiation of mouse embryonic stem cells.

Al Tanoury Z, Gaouar S, Piskunov A, Ye T, Urban S, Jost B, Keime C, Davidson I, Dierich A, Rochette-Egly C

J Cell Sci. 2014 May 1;127(Pt 9):2095-105

TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3.

Martianov I, Cler E, Duluc I, Vicaire S, Philipps M, Freund JN, Davidson I

PLoS One. 2014 Feb 3;9(2):e87365

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

Alpern D, Langer D, Ballester B, Le Gras S, Romier C, Mengus G, Davidson I

Elife. 2014 Sep 10;3:e03613

Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.

Neyret-Kahn H, Benhamed M, Ye T, Le Gras S, Cossec JC, Lapaquette P, Bischof O, Ouspenskaia M, Dasso M, Seeler J, Davidson I, Dejean A

Genome Res. 2013 Oct;23(10):1563-79

Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA.

Herquel B, Ouararhni K, Martianov I, Le Gras S, Ye T, Keime C, Lerouge T, Jost B, Cammas F, Losson R, Davidson I

Nat Struct Mol Biol. 2013 Mar;20(3):339-46

MITF, the Janus transcription factor of melanoma.

Koludrovic D, Davidson I

Future Oncol. 2013 Feb;9(2):235-44

Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.

Raverdeau M, Gely-Pernot A, Feret B, Dennefeld C, Benoit G, Davidson I, Chambon P, Mark M, Ghyselinck NB

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16582-7

Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.

Moutier E, Ye T, Choukrallah MA, Urban S, Osz J, Chatagnon A, Delacroix L, Langer D, Rochel N, Moras D, Benoit G, Davidson I

J Biol Chem. 2012 Jul 27;287(31):26328-41

Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.

Berlin I, Denat L, Steunou AL, Puig I, Champeval D, Colombo S, Roberts K, Bonvin E, Bourgeois Y, Davidson I, Delmas V, Nieto L, Goding CR, Larue L

Mol Cell Biol. 2012 Apr;32(7):1237-47

Cdx2 determines the fate of postnatal intestinal endoderm.

Stringer EJ, Duluc I, Saandi T, Davidson I, Bialecka M, Sato T, Barker N, Clevers H, Pritchard CA, Winton DJ, Wright NA, Freund JN, Deschamps J, Beck F

Development. 2012 Feb;139(3):465-74

Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.

Choukrallah MA, Kobi D, Martianov I, Pijnappel WW, Mischerikow N, Ye T, Heck AJ, Timmers HT, Davidson I

Nucleic Acids Res. 2012 Feb;40(4):1446-59

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.

Bertolotto C, Lesueur F, Giuliano S, Strub T, de Lichy M, Bille K, Dessen P, d'Hayer B, Mohamdi H, Remenieras A, Maubec E, de la Fouchardiere A, Molinie V, Vabres P, Dalle S, Poulalhon N, Martin-Denavit T, Thomas L, Andry-Benzaquen P, Dupin N, Boitier F, Rossi A, Perrot JL, Labeille B, Robert C, Escudier B, Caron O, Brugieres L, Saule S, Gardie B, Gad S, Richard S, Couturier J, Teh BT, Ghiorzo P, Pastorino L, Puig S, Badenas C, Olsson H, Ingvar C, Rouleau E, Lidereau R, Bahadoran P, Vielh P, Corda E, Blanche H, Zelenika D, Galan P, Aubin F, Bachollet B, Becuwe C, Berthet P, Bignon YJ, Bonadona V, Bonafe JL, Bonnet-Dupeyron MN, Cambazard F, Chevrant-Breton J, Coupier I, Dalac S, Demange L, d'Incan M, Dugast C, Faivre L, Vincent-Fetita L, Gauthier-Villars M, Gilbert B, Grange F, Grob JJ, Humbert P, Janin N, Joly P, Kerob D, Lasset C, Leroux D, Levang J, Limacher JM, Livideanu C, Longy M, Lortholary A, Stoppa-Lyonnet D, Mansard S, Mansuy L, Marrou K, Mateus C, Maugard C, Meyer N, Nogues C, Souteyrand P, Venat-Bouvet L, Zattara H, Chaudru V, Lenoir GM, Lathrop M, Davidson I, Avril MF, Demenais F, Ballotti R, Bressac-de Paillerets B

Nature. 2011 Oct 19;480(7375):94-8

Front seat and back seat drivers of melanoma metastasis.

Larue L, Davidson I

Pigment Cell Melanoma Res. 2011 Oct;24(5):898-901

The TIF1alpha-related TRIM cofactors couple chromatin modifications to transcriptional regulation, signaling and tumor suppression.

Herquel B, Ouararhni K, Davidson I

Transcription. 2011 Sep-Oct;2(5):231-6.

BRCA1 is a new MITF target gene.

Beuret L, Ohanna M, Strub T, Allegra M, Davidson I, Bertolotto C, Ballotti R

Pigment Cell Melanoma Res. 2011 Aug;24(4):725-7

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.

Cortellino S, Xu J, Sannai M, Moore R, Caretti E, Cigliano A, Le Coz M, Devarajan K, Wessels A, Soprano D, Abramowitz LK, Bartolomei MS, Rambow F, Bassi MR, Bruno T, Fanciulli M, Renner C, Klein-Szanto AJ, Matsumoto Y, Kobi D, Davidson I, Alberti C, Larue L, Bellacosa A

Cell. 2011 Jul 8;146(1):67-79

Unique aspects of transcription regulation in male germ cells.

White-Cooper H, Davidson I

Cold Spring Harb Perspect Biol. 2011 Jul 1;3(7). pii: a002626

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.

Strub T, Giuliano S, Ye T, Bonet C, Keime C, Kobi D, Le Gras S, Cormont M, Ballotti R, Bertolotto C, Davidson I

Oncogene. 2011 May 19;30(20):2319-32

Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma.

Herquel B, Ouararhni K, Khetchoumian K, Ignat M, Teletin M, Mark M, Bechade G, Van Dorsselaer A, Sanglier-Cianferani S, Hamiche A, Cammas F, Davidson I, Losson R

Proc Natl Acad Sci U S A. 2011 May 17;108(20):8212-7

seqMINER: an integrated ChIP-seq data interpretation platform.

Ye T, Krebs AR, Choukrallah MA, Keime C, Plewniak F, Davidson I, Tora L

Nucleic Acids Res. 2011 Mar;39(6):e35

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene.

Kobi D, Steunou AL, Dembele D, Legras S, Larue L, Nieto L, Davidson I

Pigment Cell Melanoma Res. 2010 Jun;23(3):404-18

Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells.

Delacroix L, Moutier E, Altobelli G, Legras S, Poch O, Choukrallah MA, Bertin I, Jost B, Davidson I

Mol Cell Biol. 2010 Jan;30(1):231-44

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.

Martianov I, Choukrallah MA, Krebs A, Ye T, Legras S, Rijkers E, Van Ijcken W, Jost B, Sassone-Corsi P, Davidson I

BMC Genomics. 2010 Sep 29;11:530.

TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.

Gazit K, Moshonov S, Elfakess R, Sharon M, Mengus G, Davidson I, Dikstein R

J Biol Chem. 2009 Sep 25;284(39):26286-96

Recent advances in understanding the structure and function of general transcription factor TFIID.

Cler E, Papai G, Schultz P, Davidson I

Cell Mol Life Sci. 2009 Jul;66(13):2123-34

HMGB4, a novel member of the HMGB family, is preferentially expressed in the mouse testis and localizes to the basal pole of elongating spermatids.

Catena R, Escoffier E, Caron C, Khochbin S, Martianov I, Davidson I

Biol Reprod. 2009 Feb;80(2):358-66

The histone deacetylase SIRT1 controls male fertility in mice through regulation of hypothalamic-pituitary gonadotropin signaling.

Kolthur-Seetharam U, Teerds K, de Rooij DG, Wendling O, McBurney M, Sassone-Corsi P, Davidson I

Biol Reprod. 2009 Feb;80(2):384-91

Specialization of the general transcriptional machinery in male germ cells.

Kolthur-Seetharam U, Martianov I, Davidson I

Cell Cycle. 2008 Nov 15;7(22):3493-8

Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells.

Goodall J, Carreira S, Denat L, Kobi D, Davidson I, Nuciforo P, Sturm RA, Larue L, Goding CR

Cancer Res. 2008 Oct 1;68(19):7788-94.

TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.

Voulgari A, Voskou S, Tora L, Davidson I, Sasazuki T, Shirasawa S, Pintzas A

Mol Cancer Res. 2008 Jun;6(6):1071-83.

TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1.

Brancorsini S, Davidson I, Sassone-Corsi P

Cell Cycle. 2008 May 15;7(10):1415-22

Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth.

Fadloun A, Kobi D, Delacroix L, Dembele D, Michel I, Lardenois A, Tisserand J, Losson R, Mengus G, Davidson I

Oncogene. 2008 Jan 17;27(4):477-89

The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.

Fadloun A, Kobi D, Pointud JC, Indra AK, Teletin M, Bole-Feysot C, Testoni B, Mantovani R, Metzger D, Mengus G, Davidson I

Development. 2007 Aug;134(16):2947-58

Abnormal sperm in mice lacking the Taf7l gene

Cheng Y, Buffone MG, Kouadio M, Goodheart M, Page DC, Gerton GL, Davidson I, Wang PJJ

Mol Cell Biol. 2007 Apr;27(7):2582-9

Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

Govin J, Escoffier E, Rousseaux S, Kuhn L, Ferro M, Thevenon J, Catena R, Davidson I, Garin J, Khochbin S, Caron C

J Cell Biol. 2007 Jan 29;176(3):283-94.

TBP as a candidate gene for mental retardation in patients with subtelomeric 6q deletions.

Rooms L, Reyniers E, Scheers S, van Luijk R, Wauters J, Van Aerschot L, Callaerts-Vegh Z, D'Hooge R, Mengus G, Davidson I, Courtens W, Kooy RF

Eur J Hum Genet. 2006 Oct;14(10):1090-6

Changes in intranuclear chromatin architecture induce bipolar nuclear localization of histone variant H1T2 in male haploid spermatids.

Catena R, Ronfani L, Sassone-Corsi P, Davidson I

Dev Biol. 2006 Aug 1;296(1):231-238.

TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.

Mengus G, Fadloun A, Kobi D, Thibault C, Perletti L, Michel I, Davidson I

EMBO J. 2005 Aug 3;24(15):2753-67

Proteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells.

Catena R, Argentini M, Martianov I, Parello C, Brancorsini S, Parvinen M, Sassone-Corsi P, Davidson I

FEBS Lett. 2005 Jun 20;579(16):3401-10.

A functional interaction between ATF7 and TAF12 that is modulated by TAF4.

Hamard PJ, Dalbies-Tran R, Hauss C, Davidson I, Kedinger C, Chatton B

Oncogene. 2005 May 12;24(21):3472-83.

Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis.

Martianov I, Brancorsini S, Catena R, Gansmuller A, Kotaja N, Parvinen M, Sassone-Corsi P, Davidson I

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2808-13

RNA polymerase II transcription in murine cells lacking the TATA binding protein.

Martianov I, Viville S, Davidson I

Science. 2002 Nov 1;298(5595):1036-9.

The Role of the TEF Transcription Factors in Cardiogenesis and Other Developmental Processes.

Jacquemin P, Davidson I

Trends Cardiovasc Med. 1997 Aug;7(6):192-7