Garaeva N, Fatkhullin B, Murzakhanov F, Gafurov M, Golubev A, Bikmullin A, Glazyrin M, Kieffer B, Jenner L, Klochkov V, Aganov A, Rogachev A, Ivankov O, Validov S, Yusupov M, Usachev K

Structure. 2023 11 14;:

In vitro characterization of the full-length human dynein-1 cargo adaptor BicD2.

Fagiewicz R, Crucifix C, Klos T, Deville C, Kieffer B, Nominé Y, Busselez J, Rossolillo P, Schmidt H

Structure. 2022 09 14;:

PATAS, a First-in-Class Therapeutic Peptide Biologic, Improves Whole-Body Insulin Resistance and Associated Comorbidities In Vivo.

Schreyer E, Obringer C, Messaddeq N, Kieffer B, Zimmet P, Fleming A, Geberhiwot T, Marion V

Diabetes. 2022 07 13;:

A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway.

Kuznik NC, Solozobova V, Lee II, Jung N, Yang L, Nienhaus K, Ntim EA, Rottenberg JT, Muhle-Goll C, Kumar AR, Peravali R, Gräßle S, Gourain V, Deville C, Cato L, Neeb A, Dilger M, Cramer von Clausbruch CA, Weiss C, Kieffer B, Nienhaus GU, Brown M, Bräse S, Cato ACB

iScience. 2022 May 20;25(5):104175

Androgen receptor-mediated transcriptional repression targets cell plasticity in prostate cancer.

Erdmann É, Ould Madi Berthélémy P, Cottard F, Angel CZ, Schreyer E, Ye T, Morlet B, Negroni L, Kieffer B, Céraline J

Mol Oncol. 2021 Dec 17;:

Fluorine NMR study of proline-rich sequences using fluoroprolines.

Sinnaeve D, Ben Bouzayene A, Ottoy E, Hofman GJ, Erdmann E, Linclau B, Kuprov I, Martins JC, Torbeev V, Kieffer B

Magn Reson (Gott). 2021 11 9;2(2):795-813

Conformational editing of intrinsically disordered protein by α-methylation.

Bauer V, Schmidtgall B, Gógl G, Dolenc J, Osz J, Nominé Y, Kostmann C, Cousido-Siah A, Mitschler A, Rochel N, Travé G, Kieffer B, Torbeev V

Chem Sci. 2020 Nov 4;12(3):1080-1089

Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer.

Belorusova AY, Bourguet M, Hessmann S, Chalhoub S, Kieffer B, Cianférani S, Rochel N

Nucleic Acids Res.. 2020 Sep 29;:

Self-organization properties of a GPCR binding peptide incorporating fluorinated tail studied by fluorine NMR.

Jourdain de Muizon C, Ramanoudjame S, Esteoulle L, Ling C, Brou G, Anton N, Vandamme T, Delsuc MA, Bonnet D, Kieffer B

Chembiochem. 2020 Sep 28;:

Synthesis and conformational properties of 3,4-difluoro-L-prolines.

Hofman GJ, Ottoy E, Light ME, Kieffer B, Martins JC, Kuprov I, Sinnaeve D, Linclau B

J. Org. Chem.. 2019 Feb 19;:

Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase.

Mauro E, Lesbats P, Lapaillerie D, Chaignepain S, Maillot, Oladosu O, Robert X, Fiorini F, Kieffer B, Bouaziz S, Gouet P, Ruff M, Parissi V

Nucleic Acids Res.. 2019 02 15;:

ZMIZ1 Variants Cause a Syndromic Neurodevelopmental Disorder.

Carapito R, Ivanova EL, Morlon A, Meng L, Molitor A, Erdmann E, Kieffer B, Pichot A, Naegely L, Kolmer A, Paul N, Hanauer A, Tran Mau-Them F, Jean-Marçais N, Hiatt SM, Cooper GM, Tvrdik T, Muir AM, Dimartino C, Chopra M, Amiel J, Gordon CT, Dutreux F, Garde A, Thauvin-Robinet C, Wang X, Leduc MS, Phillips M, Crawford HP, Kukolich MK, Hunt D, Harrison V, Kharbanda M, , , Smigiel R, Gold N, Hung CY, Viskochil DH, Dugan SL, Bayrak-Toydemir P, Joly-Helas G, Guerrot AM, Schluth-Bolard C, Rio M, Wentzensen IM, McWalter K, Schnur RE, Lewis AM, Lalani SR, Mensah-Bonsu N, Céraline J, Sun Z, Ploski R, Bacino CA, Mefford HC, Faivre L, Bodamer O, Chelly J, Isidor B, Bahram S

Am. J. Hum. Genet.. 2018 Dec 26;:

Modulation of RXR-DNA complex assembly by DNA context.

Osz J, McEwen AG, Wolf J, Poussin-Courmontagne P, Peluso-Iltis C, Chebaro Y, Kieffer B, Rochel N

Mol. Cell. Endocrinol.. 2018 Nov 23;:

Total chemical synthesis and biophysical properties of a designed soluble 24 kDa amyloid analogue.

Boehringer R, Kieffer B, Torbeev V

Chem Sci. 2018 Jul 7;9(25):5594-5599

An Amyloidogenic Sequence at the N-Terminus of the Androgen Receptor Impacts Polyglutamine Aggregation.

Oppong E, Stier G, Gaal M, Seeger R, Stoeck M, Delsuc MA, Cato ACB, Kieffer B

Biomolecules. 2017 Jun 19;7(2):

Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.

Khusainov I, Vicens Q, Ayupov R, Usachev K, Myasnikov A, Simonetti A, Validov S, Kieffer B, Yusupova G, Yusupov M, Hashem Y

EMBO J.. 2017 Jun;:

Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.

Bourbigot S, Dock-Bregeon AC, Eberling P, Coutant J, Kieffer B, Lebars I

RNA. 2016 Dec;22(12):1844-1858

Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity.

Schöne S, Jurk M, Helabad MB, Dror I, Lebars I, Kieffer B, Imhof P, Rohs R, Vingron M, Thomas-Chollier M, Meijsing SH

Nat Commun. 2016 Sep;7:12621

Backbone 1H, 15N, 13C NMR assignment of the 518-627 fragment of the androgen receptor encompassing N-terminal and DNA binding domains.

Meyer S, Wang YH, Pérez-Escrivà P, Kieffer B

Biomol NMR Assign. 2016 Apr;10(1):175-8

Solution Behavior of the Intrinsically Disordered N-Terminal Domain of Retinoid X Receptor α in the Context of the Full-Length Protein.

Belorusova AY, Osz J, Petoukhov MV, Peluso-Iltis C, Kieffer B, Svergun DI, Rochel N

Biochemistry. 2016 Mar;55(12):1741-8

NMR WaterLOGSY Reveals Weak Binding of Bisphenol A with Amyloid Fibers of a Conserved 11 Residue Peptide from Androgen Receptor.

Asencio-Hernández J, Kieffer B, Delsuc MA

PLoS ONE. 2016 ;11(9):e0161948

Disorder-to-order transition of MAGI-1 PDZ1 C-terminal extension upon peptide binding: thermodynamic and dynamic insights.

Ramirez J, Recht R, Charbonnier S, Ennifar E, Atkinson RA, Trave G, Nomine Y, Kieffer B

Biochemistry. 2015 Feb 17;54(6):1327-37

Accurate protein-peptide titration experiments by nuclear magnetic resonance using low-volume samples.

Kohler C, Recht R, Quinternet M, de Lamotte F, Delsuc MA, Kieffer B

Methods Mol Biol. 2015;1286:279-96

A fully enzymatic method for site-directed spin labeling of long RNA.

Lebars I, Vileno B, Bourbigot S, Turek P, Wolff P, Kieffer B

Nucleic Acids Res. 2014 Sep;42(15):e117

DNA binding by Sgf11 protein affects histone H2B deubiquitination by Spt-Ada-Gcn5-acetyltransferase (SAGA).

Koehler C, Bonnet J, Stierle M, Romier C, Devys D, Kieffer B

J Biol Chem. 2014 Mar 28;289(13):8989-99

Production and characterization of a retinoic acid receptor RARgamma construction encompassing the DNA binding domain and the disordered N-terminal proline rich domain.

Martinez-Zapien D, Delsuc MA, Trave G, Lutzing R, Rochette-Egly C, Kieffer B

Protein Expr Purif. 2014 Mar;95:113-20

Efficient denoising algorithms for large experimental datasets and their applications in Fourier transform ion cyclotron resonance mass spectrometry.

Chiron L, van Agthoven MA, Kieffer B, Rolando C, Delsuc MA

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1385-90

Heteronuclear NMR provides an accurate assessment of therapeutic insulin's quality.

Quinternet M, Starck JP, Delsuc MA, Kieffer B

J Pharm Biomed Anal. 2013 May 5;78-79:252-4

The GIP gamma-tubulin complex-associated proteins are involved in nuclear architecture in Arabidopsis thaliana.

Batzenschlager M, Masoud K, Janski N, Houlne G, Herzog E, Evrard JL, Baumberger N, Erhardt M, Nomine Y, Kieffer B, Schmit AC, Chaboute ME

Front Plant Sci. 2013 Nov 27;4:480

The determination of protein structures by NMR: a complicated optimization problem.

Nomine Y, Kieffer B

. 2012 Jun-aug;364:48-55.

Thermal stability of chicken brain alpha-spectrin repeat 17: a spectroscopic study.

Brenner AK, Kieffer B, Trave G, Froystein NA, Raae AJ

J Biomol NMR. 2012 Jun;53(2):71-83

Thermodynamics of Zn2+ binding to Cys2His2 and Cys2HisCys zinc fingers and a Cys4 transcription factor site.

Rich AM, Bombarda E, Schenk AD, Lee PE, Cox EH, Spuches AM, Hudson LD, Kieffer B, Wilcox DE

J Am Chem Soc. 2012 Jun 27;134(25):10405-18

Solution structure analysis of the HPV16 E6 oncoprotein reveals a self-association mechanism required for E6-mediated degradation of p53.

Zanier K, ould M'hamed ould Sidi A, Boulade-Ladame C, Rybin V, Chappelle A, Atkinson A, Kieffer B, Trave G

Structure. 2012 Apr 4;20(4):604-17

Unraveling complex small-molecule binding mechanisms by using simple NMR spectroscopy.

Quinternet M, Starck JP, Delsuc MA, Kieffer B

Chemistry. 2012 Mar 26;18(13):3969-74

Insight into peptide self-assembly from anisotropic rotational diffusion derived from C-13 NMR relaxation.

Sinnaeve D, Delsuc MA, Martins JC, Kieffer B

. 2012;3(4):1284-92.

Strategies for bacterial expression of protein-peptide complexes: application to solubilization of papillomavirus E6.

Sidi AO, Babah KO, Brimer N, Nomine Y, Romier C, Kieffer B, Pol SV, Trave G, Zanier K

Protein Expr Purif. 2011 Nov;80(1):8-16

Surface plasmon resonance analysis of the binding of high-risk mucosal HPV E6 oncoproteins to the PDZ1 domain of the tight junction protein MAGI-1.

Fournane S, Charbonnier S, Chapelle A, Kieffer B, Orfanoudakis G, Trave G, Masson M, Nomine Y

J Mol Recognit. 2011 Jul-Aug;24(4):511-23

The structural and dynamic response of MAGI-1 PDZ1 with noncanonical domain boundaries to the binding of human papillomavirus E6.

Charbonnier S, Nomine Y, Ramirez J, Luck K, Chapelle A, Stote RH, Trave G, Kieffer B, Atkinson RA

J Mol Biol. 2011 Mar 11;406(5):745-63

Putting into practice domain-linear motif interaction predictions for exploration of protein networks.

Luck K, Fournane S, Kieffer B, Masson M, Nomine Y, Trave G

PLoS One. 2011;6(11):e25376

HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangements.

Lebars I, Martinez-Zapien D, Durand A, Coutant J, Kieffer B, Dock-Bregeon AC

Nucleic Acids Res. 2010 Nov 1;38(21):7749-63

Vinexinss, an atypical "sensor" of retinoic acid receptor gamma signaling: union and sequestration, separation, and phosphorylation.

Lalevee S, Bour G, Quinternet M, Samarut E, Kessler P, Vitorino M, Bruck N, Delsuc MA, Vonesch JL, Kieffer B, Rochette-Egly C

FASEB J. 2010 Nov;24(11):4523-34

The structural plasticity of SCA7 domains defines their differential nucleosome-binding properties.

Bonnet J, Wang YH, Spedale G, Atkinson RA, Romier C, Hamiche A, Pijnappel WW, Timmers HT, Tora L, Devys D, Kieffer B

EMBO Rep. 2010 Aug;11(8):612-8

Structure determination of the minimal complex between Tfb5 and Tfb2, two subunits of the yeast transcription/DNA-repair factor TFIIH: a retrospective study.

Kainov DE, Cura V, Vitorino M, Nierengarten H, Poussin P, Kieffer B, Cavarelli J, Poterszman A

Acta Crystallogr D Biol Crystallogr. 2010 Jul;66(Pt 7):745-55

Prevalence of intrinsic disorder in the hepatitis C virus ARFP/Core+1/S protein.

Boumlic A, Nomine Y, Charbonnier S, Dalagiorgou G, Vassilaki N, Kieffer B, Trave G, Mavromara P, Orfanoudakis G

FEBS J. 2010 Feb;277(3):774-89

The solution structure and self-association properties of the cyclic lipodepsipeptide pseudodesmin A support its pore-forming potential.

Sinnaeve D, Hendrickx PM, Van Hemel J, Peys E, Kieffer B, Martins JC

Chemistry. 2009 Nov 23;15(46):12653-62.

SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein.

Olieric V, Wolff P, Takeuchi A, Bec G, Birck C, Vitorino M, Kieffer B, Beniaminov A, Cavigiolio G, Theil E, Allmang C, Krol A, Dumas P

Biochimie. 2009 Aug;91(8):1003-9

Defining the minimal interacting regions of the tight junction protein MAGI-1 and HPV16 E6 oncoprotein for solution structure studies.

Charbonnier S, Stier G, Orfanoudakis G, Kieffer B, Atkinson RA, Trave G

Protein Expr Purif. 2008 Jul;60(1):64-73

Multiple conformations of the metal-bound pyoverdine PvdI, a siderophore of Pseudomonas aeruginosa: a nuclear magnetic resonance study.

Wasielewski E, Tzou DL, Dillmann B, Czaplicki J, Abdallah MA, Atkinson RA, Kieffer B

Biochemistry. 2008 Mar 18;47(11):3397-406

Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy.

Vitorino M, Coin F, Zlobinskaya O, Atkinson RA, Moras D, Egly JM, Poterszman A, Kieffer B

J Mol Biol. 2007 Apr 27;368(2):473-80

NMR in the SPINE Structural Proteomics project.

Ab E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks T, Dotsch V, Engelke F, Folkers GE, Griesinger C, Gronwald W, Gunther U, Habeck M, de Jong RN, Kalbitzer HR, Kieffer B, Leeflang BR, Loss S, Luchinat C, Marquardsen T, Moskau D, Neidig KP, Nilges M, Piccioli M, Pierattelli R, Rieping W, Schippmann T, Schwalbe H, Trave G, Trenner J, Wohnert J, Zweckstetter M, Kaptein R

Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1150-61

Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis.

Nomine Y, Masson M, Charbonnier S, Zanier K, Ristriani T, Deryckere F, Sibler AP, Desplancq D, Atkinson RA, Weiss E, Orfanoudakis G, Kieffer B, Trave G

Mol Cell. 2006 Mar 3;21(5):665-78.

13C, 15N and 1H resonance assignment of the PDZ1 domain of MAGI-1 using QUASI.

Charbonnier S, Coutouly MA, Kieffer B, Trave G, Atkinson RA

J Biomol NMR. 2006;36 Suppl 1:33.

The structure-activity relationship of ferric pyoverdine bound to its outer membrane transporter: implications for the mechanism of iron uptake.

Schons V, Atkinson RA, Dugave C, Graff R, Mislin GL, Rochet L, Hennard C, Kieffer B, Abdallah MA, Schalk IJ

Biochemistry. 2005 Nov 1;44(43):14069-79.

A low-temperature heteronuclear NMR study of two exchanging conformations of metal-bound pyoverdin PaA from Pseudomonas aeruginosa.

Tzou DL, Wasielewski E, Abdallah MA, Kieffer B, Atkinson RA

Biopolymers. 2005 Oct 15;79(3):139-49.

Combining inducible protein overexpression with NMR-grade triple isotope labeling in the cyanobacterium Anabaena sp. PCC 7120.

Desplancq D, Bernard C, Sibler AP, Kieffer B, Miguet L, Potier N, Van Dorsselaer A, Weiss E

BioTechniques. 2005 Sep;39(3):405-11

Dynamics and metal exchange properties of C4C4 RING domains from CNOT4 and the p44 subunit of TFIIH.

Houben K, Wasielewski E, Dominguez C, Kellenberger E, Atkinson RA, Timmers HT, Kieffer B, Boelens R

J Mol Biol. 2005 Jun 10;349(3):621-37

Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions.

Kellenberger E, Dominguez C, Fribourg S, Wasielewski E, Moras D, Poterszman A, Boelens R, Kieffer B

J Biol Chem. 2005 May 27;280(21):20785-92

1H and 15N resonance assignment, secondary structure and dynamic behaviour of the C-terminal domain of human papillomavirus oncoprotein E6.

Nomine Y, Charbonnier S, Miguet L, Potier N, Van Dorsselaer A, Atkinson RA, Trave G, Kieffer B

J Biomol NMR. 2005 Feb;31(2):129-41.

Domain architecture of the p62 subunit from the human transcription/repair factor TFIIH deduced by limited proteolysis and mass spectrometry analysis.

Jawhari A, Boussert S, Lamour V, Atkinson RA, Kieffer B, Poch O, Potier N, van Dorsselaer A, Moras D, Poterszman A

Biochemistry. 2004 Nov 16;43(45):14420-30.

Structural characterization of the cysteine-rich domain of TFIIH p44 subunit.

Fribourg S, Kellenberger E, Rogniaux H, Poterszman A, Van Dorsselaer A, Thierry JC, Egly JM, Moras D, Kieffer B

J Biol Chem. 2000 Oct 13;275(41):31963-71.