Fiche publication
Date publication
mai 2025
Journal
Cancers
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GANGI Afshin
,
Pr NOEL Georges
,
Pr DE MATHELIN Michel
,
Dr LHERMITTE Benoît
,
Dr BURCKEL Hélène
,
Dr PO Chrystelle
,
Dr CEBULA Hélène
,
Pr PROUST François
,
Dr LE FEVRE Clara
,
Dr CAZZATO Roberto-Luigi
Tous les auteurs :
Cebula H, Po C, Mura C, Lhermitte B, Cazzato RL, Rame M, Le Fèvre C, Todeschi J, Mallereau CH, Gangi A, Noël G, de Mathelin M, Proust F, Burckel H
Lien Pubmed
Résumé
Cryotherapy involves the insertion of cryoprobes into tumors to induce cell destruction through exposure to extremely low temperatures over several minutes. This localized treatment modality may enhance the efficacy of established therapies, such as radiotherapy, particularly for glioblastomas. Our study aimed to provide proof-of-concept for the efficacy of combining cryotherapy and radiotherapy in the treatment of subcutaneous murine brain tumors (GL-261) in immunocompetent C57BL/6 mice.
Mots clés
apparent diffusion coefficient, cryotherapy, glioblastoma, radiation, radiotherapy
Référence
Cancers (Basel). 2025 05 17;17(10):
