Pr DUMOND Hélène

Fiche personne

Coordonnées

CRAN
Bd des Aiguillettes
BP 70239
54506 VANDOEUVRE-LES-NANCY Cedex

03 72 74 61 15

Territoire

Lorraine

Statut

Enseignant-Chercheur

Affiliation

Université de Lorraine (UL)

Centre de Recherche en Automatique de Nancy (CRAN) - UMR 7039 (CRAN)

Équipes/plateformes

UMR 7039 - Equipe "Biologie, Signaux et Systèmes en Cancérologie et Neurosciences (BioSIS)"

Projets

Impact anti-tumoral de l’expression et de la fonctionnalité du récepteur membranaire des œstrogènes GPER sur les glioblastomes

2022 - Porteur du projet : Pr DUMOND Hélène

Mécanismes d'action des œstrogènes et progestatifs dans la progression des gliomes de bas grade (Pro-Glio)

2020 - Porteur du projet : Dr RECH Fabien - Partenaire : Dr DUBOIS-POT-SCHNEIDER Hélène , Pr DUMOND Hélène , Dr PINEL Sophie , Pr TAILLANDIER Luc , Pr GAUCHOTTE Guillaume

Etude prospective de validation d'ERα36, nouveau marqueur moléculaire pronostique de progression tumorale dans les cancers du sein

2015 - Porteur du projet : Pr DUMOND Hélène

Characterization of ER-alpha-36 natural and synthetic ligands for the modulation of hormone-sensitive tumor initiation and progression

2013 - Porteur du projet : Pr DUMOND Hélène

Publications

Nuclear and membrane-bound hormone receptors in glioblastoma: Expression, functionality, and therapeutic implications.

Gantner A, Dubois-Pot-Schneider H, Dumond H

Neurooncol Adv. 2025 12 9;8(1):vdaf252

Estrogen signaling in healthy and tumor brain.

Hirtz A, Rech F, Dubois-Pot-Schneider H, Dumond H

Steroids. 2023 08 3;:109285

Molecular Characterization of the Dual Effect of the GPER Agonist G-1 in Glioblastoma.

Hirtz A, Bailly Y, Rech F, Pierson J, Dumond H, Dubois-Pot-Schneider H

Int J Mol Sci. 2022 11 18;23(22):

Identification of Gender- and Subtype-Specific Gene Expression Associated with Patient Survival in Low-Grade and Anaplastic Glioma in Connection with Steroid Signaling.

Hirtz A, Lebourdais N, Thomassin M, Rech F, Dumond H, Dubois-Pot-Schneider H

Cancers (Basel). 2022 08 25;14(17):

GPER Agonist G-1 Disrupts Tubulin Dynamics and Potentiates Temozolomide to Impair Glioblastoma Cell Proliferation.

Hirtz A, Lebourdais N, Rech F, Bailly Y, Vaginay A, Smaïl-Tabbone M, Dubois-Pot-Schneider H, Dumond H

Cells. 2021 12 7;10(12):

Astrocytoma: A Hormone-Sensitive Tumor?

Hirtz A, Rech F, Dubois-Pot-Schneider H, Dumond H

Int J Mol Sci. 2020 Nov 30;21(23):

A statistical methodology to select covariates in high-dimensional data under dependence. Application to the classification of genetic profiles in oncology.

Bastien B, Boukhobza T, Dumond H, Gégout-Petit A, Muller-Gueudin A, Thiébaut C

J Appl Stat. 2020 10 27;49(3):764-781

The Role of ERα36 in Development and Tumor Malignancy.

Thiebaut C, Konan HP, Guerquin MJ, Chesnel A, Livera G, Le Romancer M, Dumond H

Int J Mol Sci. 2020 Jun 9;21(11):

Dual Epigenetic Regulation of ERα36 Expression in Breast Cancer Cells.

Thiebaut C, Chesnel A, Merlin JL, Chesnel M, Leroux A, Harlé A, Dumond H

Int J Mol Sci. 2019 May 29;20(11):

Low-Dose Alkylphenol Exposure Promotes Mammary Epithelium Alterations and Transgenerational Developmental Defects, But Does Not Enhance Tumorigenic Behavior of Breast Cancer Cells.

Chamard-Jovenin C, Thiebaut C, Chesnel A, Bresso E, Morel C, Smail-Tabbone M, Devignes MD, Boukhobza T, Dumond H

Front Endocrinol (Lausanne). 2017 ;8:272

Mammary epithelial cell phenotype disruption in vitro and in vivo through ERalpha36 overexpression.

Thiebaut C, Chamard-Jovenin C, Chesnel A, Morel C, Djermoune EH, Boukhobza T, Dumond H

PLoS ONE. 2017 ;12(3):e0173931

From ERalpha66 to ERalpha36: a generic method for validating a prognosis marker of breast tumor progression.

Chamard-Jovenin C, Jung AC, Chesnel A, Abecassis J, Flament S, Ledrappier S, Macabre C, Boukhobza T, Dumond H

BMC Syst Biol. 2015 Jun 17;9(1):28

Mullerian inhibiting substance in the caudate amphibian Pleurodeles waltl.

Al-Asaad I, Chardard D, di Clemente N, Picard JY, Dumond H, Chesnel A, Flament S

Endocrinology. 2013 Oct;154(10):3931-6

An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism.

Ajj H, Chesnel A, Pinel S, Plenat F, Flament S, Dumond H

PLoS One. 2013 Apr 23;8(4):e61758

Busulfan-mediated germ cell depletion does not alter gonad differentiation in the urodele amphibian Pleurodeles waltl.

Al-Asaad I, Dumond H, Chardard D, Chesnel A, Flament S

Sex Dev. 2012;6(4):188-200

Temporal and spatial SOX9 expression patterns in the course of gonad development of the caudate amphibian Pleurodeles waltl.

Dumond H, Al-Asaad I, Chesnel A, Chardard D, Boizet-Bonhoure B, Flament S, Kuntz S

J Exp Zool B Mol Dev Evol. 2011 May 15;316B(3):199-211

[Is leptin the missing link between osteoarthritis and obesity?].

Terlain B, Dumond H, Presle N, Mainard D, Bianchi A, Loeuille D, Netter P, Pottie P

Ann Pharm Fr. 2005 Jun;63(3):186-93.

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