Dr ANSELME Karine

Self-rolling film for drug delivery to limit colonic inflammation induced after radiation exposure.

Amarante-Silva D, Demarquay C, Nottelet B, Grosjean M, Ouedraogo S, Milliat F, Anselme K, Ponche A, Mathieu N

iScience. 2026 09 18;29(9):117453

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo.

Bouyer D, Mutlu H, Charmette C, Randrianaridera E, Adaidi Z, Hedna R, Pieuchot L, Pluvy I, Anselme K, Couturier N, Mericq JP, Ponche A, Brigaud I

Adv Healthc Mater. 2026 08 24;:e71641

The O‑GlcNAcase inhibition by Thiamet G disrupts the AngioMatrix signature of the Glioblastoma secretome in silico and impairs its angiogenic capacity in vitro.

Gil de Castro MA, Queiroz T, de Menezes AC, Borges AC, Nogueira FC, Brigaud I, Anselme K, Pieuchot L, Dias WB, de Abreu Pereira D, Carneiro K

J Mol Biol. 2026 06 9;:169906

Breast implant silicone exposure induces immunogenic response and autoimmune markers in human periprosthetic tissue.

Pluvy I, Randrianaridera E, Tahmaz I, Melin M, Gindraux F, Keime C, Ponche A, Petithory T, Pieuchot L, Anselme K, Brigaud I

Biomaterials. 2024 12 18;317:123025

Fabrication and characterization of thin self-rolling film for anti-inflammatory drug delivery.

Ouedraogo S, Grosjean M, Brigaud I, Carneiro K, Luchnikov V, Mathieu N, Garric X, Nottelet B, Anselme K, Pieuchot L, Ponche A

Colloids Surf B Biointerfaces. 2024 06 13;241:114039

In silico analysis shows that dynamic changes in curvature guide cell migration over long distances.

Manifacier I, Carlin G, Liu D, Vassaux M, Pieuchot L, Luchnikov V, Anselme K, Milan JL

Biomech Model Mechanobiol. 2023 10 24;:

Response of Osteoblasts on Amine-Based Nanocoatings Correlates with the Amino Group Density.

Seemann S, Dubs M, Koczan D, Salapare HS, Ponche A, Pieuchot L, Petithory T, Wartenberg A, Staehlke S, Schnabelrauch M, Anselme K, Nebe JB

Molecules. 2023 09 7;28(18):

Curvature in Biological Systems: Its quantification, Emergence and Implications Across the Scales.

Schamberger B, Roschger A, Ziege R, Anselme K, Amar MB, Bykowski M, Castro APG, Cipitria A, Coles R, Dimova R, Eder M, Ehrig S, Escudero LM, Evans ME, Fernandes PR, Fratzl P, Geris L, Gierlinger N, Hannezo E, Iglič A, Kirkensgaard JJK, Kollmannsberger P, Kowalewska Ł, Kurniawan NA, Papantoniou I, Pieuchot L, Pires THV, Renner L, Sageman-Furnas A, Schröder-Turk GE, Sengupta A, Sharma VR, Tagua A, Tomba C, Trepat X, Waters SL, Yeo E, Bidan CM, Dunlop JWC

Adv Mater. 2022 12 3;:e2206110

In Vitro and In Vivo Cell-Interactions with Electrospun Poly (Lactic-Co-Glycolic Acid) (PLGA): Morphological and Immune Response Analysis.

Chor A, Takiya CM, Dias ML, Gonçalves RP, Petithory T, Cypriano J, de Andrade LR, Farina M, Anselme K

Polymers (Basel). 2022 10 21;14(20):

Bioresorbable Bilayered Elastomer/Hydrogel Constructs with Gradual Interfaces for the Fast Actuation of Self-Rolling Tubes.

Grosjean M, Ouedraogo S, Déjean S, Garric X, Luchnikov V, Ponche A, Mathieu N, Anselme K, Nottelet B

ACS Appl Mater Interfaces. 2022 09 19;:

New Phenotype and Mineralization of Biogenic Iron Oxide in Magnetotactic Bacteria.

Baaziz W, Ghica C, Cypriano J, Abreu F, Anselme K, Ersen O, Farina M, Werckmann J

Nanomaterials (Basel). 2021 Nov 25;11(12):

Size-Dependent Internalization Efficiency of Macrophages from Adsorbed Nanoparticle-Based Monolayers.

Petithory T, Pieuchot L, Josien L, Ponche A, Anselme K, Vonna L

Nanomaterials (Basel). 2021 Jul 30;11(8):

Topographical curvature is sufficient to control epithelium elongation.

Rougerie P, Pieuchot L, Dos Santos RS, Marteau J, Bigerelle M, Chauvy PF, Farina M, Anselme K

Sci Rep. 2020 Sep 8;10(1):14784

In Vitro Degradation of Electrospun Poly(Lactic-Co-Glycolic Acid) (PLGA) for Oral Mucosa Regeneration.

Chor A, Gonçalves RP, Costa AM, Farina M, Ponche A, Sirelli L, Schrodj G, Gree S, Andrade LR, Anselme K, Dias ML

Polymers (Basel). 2020 Aug 18;12(8):

Surface Texturization of Breast Implants Impacts Extracellular Matrix and Inflammatory Gene Expression in Asymptomatic Capsules.

Brigaud I, Garabédian C, Bricout N, Pieuchot L, Ponche A, Deltombe R, Delille R, Atlan M, Bigerelle M, Anselme K

Plast. Reconstr. Surg.. 2020 Mar;145(3):542e-551e

Actomyosin, vimentin and LINC complex pull on osteosarcoma nuclei to deform on micropillar topography.

Tusamda Wakhloo N, Anders S, Badique F, Eichhorn M, Brigaud I, Petithory T, Vassaux M, Milan JL, Freund JN, Rühe J, Davidson PM, Pieuchot L, Anselme K

Biomaterials. 2020 Jan 2;234:119746

Surface texturation of breast implant impacts extracellular matrix and inflammatory gene expression in asymptomatic capsule.

Brigaud I, Garabédian C, Bricout N, Pieuchot L, Ponche A, Deltombe R, Delille R, Atlan M, Bigerelle M, Anselme K

Plast. Reconstr. Surg.. 2019 Dec 23;:

A biophysical model for curvature-guided cell migration.

Vassaux M, Pieuchot L, Anselme K, Bigerelle M, Milan JL

Biophys. J.. 2019 Jul 22;:

Real-Time Imaging of Bacteria/Osteoblast Dynamic Coculture on Bone Implant Material in an in Vitro Postoperative Contamination Model.

Prévost V, Anselme K, Gallet O, Hindié M, Petithory T, Valentin J, Veuillet M, Ploux L

ACS Biomater Sci Eng. 2019 Jul 8;5(7):3260-3269

Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns.

Beijer NRM, Nauryzgaliyeva ZM, Arteaga EM, Pieuchot L, Anselme K, van de Peppel J, Vasilevich AS, Groen N, Roumans N, Hebels DGAJ, Boer J

Sci Rep. 2019 Jun 24;9(1):9099

Influence of multiscale and curved structures on the migration of stem cells.

Belaud V, Petithory T, Ponche A, Mauclair C, Donnet C, Pieuchot L, Benayoun S, Anselme K

Biointerphases. 2018 Dec 31;13(6):06D408

Curvotaxis directs cell migration through cell-scale curvature landscapes.

Pieuchot L, Marteau J, Guignandon A, Dos Santos T, Brigaud I, Chauvy PF, Cloatre T, Ponche A, Petithory T, Rougerie P, Vassaux M, Milan JL, Tusamda Wakhloo N, Spangenberg A, Bigerelle M, Anselme K

Nat Commun. 2018 Sep 28;9(1):3995

Bio-sourced phosphoprotein-based synthesis of silver-doped macroporous zinc phosphates and their antibacterial properties.

Hinostroza Ramos JV, Anselme K, Simon-Masseron A, Ploux L

RSC Adv. 2018 Jul 9;8(44):25112-25122

Role of the Nucleus as a Sensor of Cell Environment Topography.

Anselme K, Wakhloo NT, Rougerie P, Pieuchot L

Adv Healthc Mater. 2018 Apr;7(8):e1701154

Antibacterial properties and compressive strength of new one-step preparation silver nanoparticles in glass ionomer cements (NanoAg-GIC).

Paiva L, Fidalgo TKS, da Costa LP, Maia LC, Balan L, Anselme K, Ploux L, Thiré RMSM

J Dent. 2018 Feb;69:102-109

Physicochemical regulation of TGF and VEGF delivery from mesoporous calcium phosphate bone substitutes.

Möller-Siegert J, Parmentier J, Laquerrière P, Ouadi A, Raisslé O, Jallot E, Nedelec JM, Vix-Guterl C, Anselme K

Nanomedicine (Lond). 2017 Jul;:

Synthesis and characterization of Ti-27.5Nb alloy made by CLAD® additive manufacturing process for biomedical applications.

Fischer M, Laheurte P, Acquier P, Joguet D, Peltier L, Petithory T, Anselme K, Mille P

Mater Sci Eng C Mater Biol Appl. 2017 Jun;75:341-348

Synergistic effects of BMP-2, BMP-6 or BMP-7 with human plasma fibronectin onto hydroxyapatite coatings: a comparative study.

Brigaud I, Agniel R, Leroy Dudal J, Kellouche S, Ponche A, Bouceba T, Mihailescu N, Sopronyi M, Viguier E, Ristoscu C, Sima F, Mihailescu IN, Carreira ACO, Sogayar MC, Gallet O, Anselme K

Acta Biomater. 2017 Apr;:

Abrogated Cell Contact Guidance on Amino-Functionalized Microgrooves.

Mörke C, Rebl H, Finke B, Dubs M, Nestler P, Airoudj A, Roucoules V, Schnabelrauch M, Körtge A, Anselme K, Helm CA, Nebe JB

ACS Appl Mater Interfaces. 2017 Mar;9(12):10461-10471

The effects of femtosecond laser-textured Ti-6Al-4V on wettability and cell response.

Raimbault O, Benayoun S, Anselme K, Mauclair C, Bourgade T, Kietzig AM, Girard-Lauriault PL, Valette S, Donnet C

Mater Sci Eng C Mater Biol Appl. 2016 Dec;69:311-20

Surface composition XPS analysis of a plasma treated polystyrene: Evolution over long storage periods.

Ba OM, Marmey P, Anselme K, Duncan AC, Ponche A

Colloids Surf B Biointerfaces. 2016 Sep;145:1-7

Effects of Fibronectin Coating on Bacterial and Osteoblast Progenitor Cells Adherence in a Co-culture Assay.

Hindié M, Wu D, Anselme K, Gallet O, Di Martino P

Adv. Exp. Med. Biol.. 2016 Jul;:

High-performance liquid chromatography as a technique to determine protein adsorption onto hydrophilic/hydrophobic surfaces.

Huang T, Anselme K, Sarrailh S, Ponche A

Int J Pharm. 2016 Jan;497(1-2):54-61

Protein covalent immobilization via its scarce thiol versus abundant amine groups: Effect on orientation, cell binding domain exposure and conformational lability.

Ba OM, Hindie M, Marmey P, Gallet O, Anselme K, Ponche A, Duncan AC

Colloids Surf B Biointerfaces. 2015 Oct;134:73-80

Strontium ranelate improves the interaction of osteoblastic cells with titanium substrates: Increase in cell proliferation, differentiation and matrix mineralization.

Querido W, Farina M, Anselme K

Biomatter. 2015 Jul 15:0.

Nucleus deformation of SaOs-2 cells on rhombic micro-pillars.

Eichhorn M, Stannard C, Anselme K, Ruhe J

J Mater Sci Mater Med. 2015 Feb;26(2):108

Different surface sensing of the cell body and nucleus in healthy primary cells and in a cancerous cell line on nanogrooves.

Davidson PM, Bigerelle M, Reiter G, Anselme K

Biointerphases. 2015 Oct 1;10(3):031004

In vitro and in vivo evaluation of the inflammatory potential of various nanoporous hydroxyapatite biomaterials.

Velard F, Schlaubitz S, Fricain JC, Guillaume C, Laurent-Maquin D, Möller-Siegert J, Vidal L, Jallot E, Sayen S, Raissle O, Nedelec JM, Vix-Guterl C, Anselme K, Amédée J, Laquerrière P

Nanomedicine (Lond). 2015 ;10(5):785-802

Inorganic-organic thin implant coatings deposited by lasers.

Sima F, Davidson PM, Dentzer J, Gadiou R, Pauthe E, Gallet O, Mihailescu IN, Anselme K

ACS Appl Mater Interfaces. 2015 Jan;7(1):911-20

Combinatorial Matrix Assisted Pulsed Laser Evaporation of a biodegradable polymer and fibronectin for protein immobilization and controlled release.

Sima F, Axente E, Iordache I, Luculescu C, Gallet O, Anselme K, Mihailescu N

Appl Surf Sci. 2014 Jul 1;306:75-9.

On the relation between surface roughness of metallic substrates and adhesion of human primary bone cells.

Anselme K, Bigerelle M

Scanning. 2014 Jan-Feb;36(1):11-20

Roughness statistical influence on cell adhesion using profilometry and multiscale analysis.

Giljean S, Bigerelle M, Anselme K

Scanning. 2014 Jan-Feb;36(1):2-10

Tuning InAs nanowire density for HEK293 cell viability, adhesion, and morphology: perspectives for nanowire-based biosensors.

Bonde S, Berthing T, Madsen MH, Andersen TK, Buch-Manson N, Guo L, Li X, Badique F, Anselme K, Nygard J, Martinez KL

ACS Appl Mater Interfaces. 2013 Nov 13;5(21):10510-9

Preparation, characterization and biological test of 3D-scaffolds based on chitosan, fibroin and hydroxyapatite for bone tissue engineering.

Lima PA, Resende CX, Soares GD, Anselme K, Almeida LE

Mater Sci Eng C Mater Biol Appl. 2013 Aug 1;33(6):3389-95

Fabrication of functional fibronectin patterns by nanosecond excimer laser direct write for tissue engineering applications.

Grigorescu S, Hindie M, Axente E, Carreiras F, Anselme K, Werckmann J, Mihailescu IN, Gallet O

J Mater Sci Mater Med. 2013 Jul;24(7):1809-21

An expert system to characterise the surfaces morphological properties according to their tribological functionalities: The relevance of a pair of roughness parameters.

Bigerelle M, Najjar D, Mathia T, Iost A, Coorevits T, Anselme K

Tribol Int. 2013 Mar;59:190-202.

Vesicular Structures Self-Assembled from Oligonucleotide-Polymer Hybrids: Mechanical Prevention of Bacterial Colonization Upon their Surface Tethering Through Hybridization.

Cottenye N, Anselme K, Ploux L, Vebert-Nardin C

Adv Funct Mater. 2012 Dec 5;22(23):4891-8.

Physical-chemical and biological behavior of an amorphous calcium phosphate thin film produced by RF-magnetron sputtering.

dos Santos EA, Moldovan S, Mateescu M, Faerber J, Acosta M, Pelletier H, Anselme K, Werckmann J

. 2012 Oct 1;32(7):2086-95.

A Method to Determine the Spatial Scale Implicated in Adhesion. Application on Human Cell Adhesion on Fractal Isotropic Rough Surfaces.

Bigerelle M, Mazeran PE, Gong W, Giljean S, Anselme K

. 2011;87(7-8):644-70.

Relative influence of surface topography and surface chemistry on cell response to bone implant materials. Part 1: physico-chemical effects.

Ponche A, Bigerelle M, Anselme K

Proc Inst Mech Eng H. 2010 Dec;224(12):1471-86.

Definition of a simple statistical parameter for the quantification of orientation in two dimensions: application to cells on grooves of nanometric depths.

Davidson P, Bigerelle M, Bounichane B, Giazzon M, Anselme K

Acta Biomater. 2010 Jul;6(7):2590-8

Temperature-programmed desorption as a tool for quantification of protein adsorption capacity in micro- and nanoporous materials.

Gadiou R, dos Santos EA, Vijayaraj M, Anselme K, Dentzer J, Soares GA, Vix-Guterl C

Colloids Surf B Biointerfaces. 2009 Oct 15;73(2):168-74

Microstructured Surfaces Cause Severe but Non-Detrimental Deformation of the Cell Nucleus

Davidson PM, Ozcelik H, Hasirci V, Reiter G, Anselme K

Adv Mater. 2009 Sep 18;21(35):3586-+

Opposite responses of cells and bacteria to micro/nanopatterned surfaces prepared by pulsed plasma polymerization and UV-irradiation.

Ploux L, Anselme K, Dirani A, Ponche A, Soppera O, Roucoules V

Langmuir. 2009 Jul 21;25(14):8161-9.

Effect of ultrasounds on the electrochemical synthesis of polypyrrole, application to the adhesion and growth of biological cells.

Lakard B, Ploux L, Anselme K, Lallemand F, Lakard S, Nardin M, Hihn JY

Bioelectrochemistry. 2009 Jun;75(2):148-57

Chemical and topographical influence of hydroxyapatite and beta-tricalcium phosphate surfaces on human osteoblastic cell behavior.

dos Santos EA, Farina M, Soares GA, Anselme K

J Biomed Mater Res A. 2009 May;89(2):510-20.

Oligonucleotide nanostructured surfaces: effect on Escherichia coli curli expression.

Cottenye N, Teixeira F Jr, Ponche A, Reiter G, Anselme K, Meier W, Ploux L, Vebert-Nardin C

Macromol Biosci. 2008 Dec 8;8(12):1161-72.

Surface energy of hydroxyapatite and beta-tricalcium phosphate ceramics driving serum protein adsorption and osteoblast adhesion.

dos Santos EA, Farina M, Soares GA, Anselme K

J Mater Sci Mater Med. 2008 Jun;19(6):2307-16

Statistical demonstration of the relative effect of surface chemistry and roughness on human osteoblast short-term adhesion.

Anselme K, Bigerelle M

J Mater Sci Mater Med. 2006 May;17(5):471-9.

Modelling approach in cell/material interactions studies.

Anselme K, Bigerelle M

Biomaterials. 2006 Mar;27(8):1187-99

Physico-chemical characteristics and protein adsorption potential of hydroxyapatite particles: influence on in vitro biocompatibility of ceramics after sintering.

Rouahi M, Champion E, Gallet O, Jada A, Anselme K

Colloids Surf B Biointerfaces. 2006 Jan 15;47(1):10-9

Removal of surface by-products from sintered hydroxyapatite: effect of a chelation treatment on fibronectin adsorption and cell adhesion.

Pellenc D, Giraudier S, Champion E, Anselme K, Larreta-Garde V, Gallet O

J Biomed Mater Res B Appl Biomater. 2006 Jan;76(1):136-42.

A kinetic approach to osteoblast adhesion on biomaterial surface.

Bigerelle M, Anselme K

J Biomed Mater Res A. 2005 Dec 1;75(3):530-40.

Bootstrap analysis of the relation between initial adhesive events and long-term cellular functions of human osteoblasts cultured on biocompatible metallic substrates.

Bigerelle M, Anselme K

Acta Biomater. 2005 Sep;1(5):499-510

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