Lopez C, Licaj I, Dumas A, Havas J, Di Meglio A, Luis IV, Pistilli B, André F, Martin AL, Delmas D, Jouannaud C, Kaderbhai C, Cherifi F, Campone M, Mouret-Reynier MA, Ruiz-de-Azua G, Menvielle G

Sci Rep. 2026 03 12;:

Phosphatidylcholine and CHPT1 as Central Drivers of Chemoresistance in Colorectal Cancer: Lipidomic and Functional Insights.

Mialhe A, Pais de Barros JP, Hermetet F, Limagne E, Ghiringhelli F, Aires V, Delmas D

Cells. 2026 02 28;15(5):

Lipid metabolism in cancer: Exploring phospholipids as potential biomarkers.

Delmas D, Mialhe A, Cotte AK, Connat JL, Bouyer F, Hermetet F, Aires V

Biomed Pharmacother. 2025 04 29;187:118095

Current Advances in the Combination of Fatty Acids and Resveratrol to Fight Ocular Diseases.

Delmas D, Perus M, Aires V, Hermetet F

Mol Nutr Food Res. 2025 04 7;:e70037

Polyunsaturated Fatty Acids: New Molecular Mechanisms and Nutritional Therapeutic Challenges.

Delmas D, Aires V

Nutrients. 2025 02 6;17(3):

VEGF-R2/CAV-1 Interaction Induced by Resveratrol/Eicosapentaenoic Acid/Docosahexaenoic Acid-Enriched Formulation through Functional Detergent-Resistant Membranes Is Associated with Decreased VEGF-A Release in ARPE-19 Cells.

Perus M, Courtaut F, Pais de Barros JP, Aires V, Hermetet F, Delmas D

Mol Nutr Food Res. 2024 05 19;:e2300893

Emergence of Lipid Droplets in the Mechanisms of Carcinogenesis and Therapeutic Responses.

Delmas D, Cotte AK, Connat JL, Hermetet F, Bouyer F, Aires V

Cancers (Basel). 2023 08 14;15(16):

Chrysin-Induced Regression of Angiogenesis via an Induction of DNA Damage Response and Oxidative Stress in In Vitro and In Vivo Models of Melanoma.

Sassi A, Fredon M, Cotte AK, Fuselier C, Schneider C, Martiny L, Monchaud D, Chekir-Ghedira L, Aires V, Delmas D

Cells. 2023 06 6;12(12):

Red Wine Extract Prevents Oxidative Stress and Inflammation in ARPE-19 Retinal Cells.

Cornebise C, Perus M, Hermetet F, Valls-Fonayet J, Richard T, Aires V, Delmas D

Cells. 2023 05 17;12(10):

Tannic Acid, A Hydrolysable Tannin, Prevents Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition to Counteract Colorectal Tumor Growth.

Barboura M, Cornebise C, Hermetet F, Guerrache A, Selmi M, Salek A, Chekir-Ghedira L, Aires V, Delmas D

Cells. 2022 11 17;11(22):

Resvega, a Nutraceutical Preparation, Affects NFκB Pathway and Prolongs the Anti-VEGF Effect of Bevacizumab in Undifferentiated ARPE-19 Retina Cells.

Sghaier R, Perus M, Cornebise C, Courtaut F, Scagliarini A, Olmiere C, Aires V, Hermetet F, Delmas D

Int J Mol Sci. 2022 10 3;23(19):

Litchi ( Sonn.): a comprehensive review of phytochemistry, medicinal properties, and product development.

Yao P, Gao Y, Simal-Gandara J, Farag MA, Chen W, Yao D, Delmas D, Chen Z, Liu K, Hu H, Xiao J, Rong X, Wang S, Hu Y, Wang Y

Food Funct. 2021 Oct 19;12(20):9527-9548

RESVEGA, a Nutraceutical Omega-3/Resveratrol Supplementation, Reduces Angiogenesis in a Preclinical Mouse Model of Choroidal Neovascularization.

Courtaut F, Aires V, Acar N, Bretillon L, Guerrera IC, Chhuon C, Pais de Barros JP, Olmiere C, Delmas D

Int J Mol Sci. 2021 Oct 13;22(20):

PD-1/PD-L1 Checkpoints and Resveratrol: A Controversial New Way for a Therapeutic Strategy.

Delmas D, Hermetet F, Aires V

Cancers (Basel). 2021 Sep 7;13(18):

VEGF-R2/Caveolin-1 Pathway of Undifferentiated ARPE-19 Retina Cells: A Potential Target as Anti-VEGF-A Therapy in Wet AMD by Resvega, an Omega-3/Polyphenol Combination.

Courtaut F, Scagliarini A, Aires V, Cornebise C, Pais de Barros JP, Olmiere C, Delmas D

Int J Mol Sci. 2021 Jun 19;22(12):

Essential Oils, and , Chemosensitize Resistant Human Uterine Sarcoma MES-SA/Dx5 Cells to Doxorubicin by Inducing Apoptosis and Targeting P-Glycoprotein.

Lahmar A, Mathey A, Aires V, Elgueder D, Vejux A, Khlifi R, Sioud F, Chekir-Ghedira L, Delmas D

Nutrients. 2021 May 19;13(5):

New Highlights of Resveratrol: A Review of Properties against Ocular Diseases.

Delmas D, Cornebise C, Courtaut F, Xiao J, Aires V

Int J Mol Sci. 2021 Jan 28;22(3):

Red Wine Extract Inhibits VEGF Secretion and Its Signaling Pathway in Retinal ARPE-19 Cells to Potentially Disrupt AMD.

Cornebise C, Courtaut F, Taillandier-Coindard M, Valls-Fonayet J, Richard T, Monchaud D, Aires V, Delmas D

Molecules. 2020 Nov 27;25(23):

Silymarin and Derivatives: From Biosynthesis to Health Benefits.

Delmas D

Molecules. 2020 May 22;25(10):

Silymarin and Cancer: A Dual Strategy in Both in Chemoprevention and Chemosensitivity.

Delmas D, Xiao J, Vejux A, Aires V

Molecules. 2020 Apr 25;25(9):

Red Wine Extract Disrupts Th17 Lymphocyte Differentiation in a Colorectal Cancer Context.

Chalons P, Courtaut F, Limagne E, Chalmin F, Cantos-Villar E, Richard T, Auger C, Chabert P, Schini-Kerth V, Ghiringhelli F, Aires V, Delmas D

Mol Nutr Food Res. 2020 Apr 18;:e1901286

Xanthohumol, a Prenylated Flavonoid from Hops, Induces DNA Damages in Colorectal Cancer Cells and Sensitizes SW480 Cells to the SN38 Chemotherapeutic Agent.

Scagliarini A, Mathey A, Aires V, Delmas D

Cells. 2020 Apr 10;9(4):

A New Highlight of Decne Properties as Potential Adjuvant in Combination with Cisplatin to Induce Cell Death of 4T1 Breast Cancer Cells In Vitro and In Vivo.

Sioud F, Amor S, Toumia IB, Lahmar A, Aires V, Chekir-Ghedira L, Delmas D

Cells. 2020 Feb 4;9(2):

Immune Th17 lymphocytes play a critical role in the multiple beneficial properties of resveratrol.

Delmas D, Limagne E, Ghiringhelli F, Aires V

Food Chem. Toxicol.. 2019 Dec 26;:111091

P-Glycoprotein 1 Affects Chemoactivities of Resveratrol against Human Colorectal Cancer Cells.

Aires V, Colin DJ, Doreau A, Di Pietro A, Heydel JM, Artur Y, Latruffe N, Delmas D

Nutrients. 2019 Sep 4;11(9):

Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model.

Doria M, Nury T, Delmas D, Moreau T, Lizard G, Vejux A

Free Radic. Biol. Med.. 2019 Apr 17;:

Identification of three-way DNA junction ligands through screening of chemical libraries and validation by complementary in vitro assays.

Duskova K, Lamarche J, Amor S, Caron C, Queyriaux N, Gaschard M, Penouilh MJ, De Robillard G, Delmas D, Devillers CH, Granzhan A, Teulade-Fichou MP, Chavarot-Kerlidou M, Therrien B, Britton S, Monchaud D

J. Med. Chem.. 2019 Apr 3;:

Phospholipid profiles and hepatocellular carcinoma risk and prognosis in cirrhotic patients.

Cotte AK, Cottet V, Aires V, Mouillot T, Rizk M, Vinault S, Binquet C, de Barros JP, Hillon P, Delmas D

Oncotarget. 2019 Mar 15;10(22):2161-2172

Study of Potential Anti-Inflammatory Effects of Red Wine Extract and Resveratrol through a Modulation of Interleukin-1-Beta in Macrophages.

Chalons P, Amor S, Courtaut F, Cantos-Villar E, Richard T, Auger C, Chabert P, Schni-Kerth V, Aires V, Delmas D

Nutrients. 2018 Dec 1;10(12):

Polyphenol Extracts from Red Wine and Grapevine: Potential Effects on Cancers.

Amor S, Châlons P, Aires V, Delmas D

Diseases. 2018 Nov 18;6(4):

Dietary polyphenols and type 2 diabetes: Human study and clinical trials.

Cao H, Ou J, Chen L, Zhang Y, Szkudelski T, Delmas D, Daglia M, Xiao J

Crit Rev Food Sci Nutr. 2018 Jul 11;:1-19

Molecular analysis of differential antiproliferative activity of resveratrol, epsilon viniferin and labruscol on melanoma cells and normal dermal cells.

Nivelle L, Aires V, Rioult D, Martiny L, Tarpin M, Delmas D

Food Chem. Toxicol.. 2018 Apr 22;116(Pt B):323-334

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance.

Cotte AK, Aires V, Fredon M, Limagne E, Derangère V, Thibaudin M, Humblin E, Scagliarini A, de Barros JP, Hillon P, Ghiringhelli F, Delmas D

Nat Commun. 2018 01 22;9(1):322

LPCAT2 controls chemoresistance in colorectal cancer.

Cotte AK, Aires V, Ghiringhelli F, Delmas D

Mol Cell Oncol. 2018 ;5(3):e1448245

Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages.

Al Azzaz J, Rieu A, Aires V, Delmas D, Chluba J, Winckler P, Bringer MA, Lamarche J, Vervandier-Fasseur D, Dalle F, Lapaquette P, Guzzo J

Front Immunol. 2018 ;9:3149

Resveratrol-Induced Changes in MicroRNA Expression in Primary Human Fibroblasts Harboring Carnitine-Palmitoyl Transferase-2 Gene Mutation, Leading to Fatty Acid Oxidation Deficiency.

Aires V, Delmas D, Djouadi F, Bastin J, Cherkaoui-Malki M, Latruffe N

Molecules. 2017 Dec 22;23(1):

Cytotoxicity of Labruscol, a New Resveratrol Dimer Produced by Grapevine Cell Suspensions, on Human Skin Melanoma Cancer Cell Line HT-144.

Nivelle L, Hubert J, Courot E, Borie N, Renault JH, Nuzillard JM, Harakat D, Clément C, Martiny L, Delmas D, Jeandet P, Tarpin M

Molecules. 2017 Nov 9;22(11):

Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation.

Limagne E, Thibaudin M, Euvrard R, Berger H, Chalons P, Végan F, Humblin E, Boidot R, Rébé C, Derangère V, Ladoire S, Apetoh L, Delmas D, Ghiringhelli F

Cell Rep. 2017 Apr;19(4):746-759

Anti-Cancer Activity of Resveratrol and Derivatives Produced by Grapevine Cell Suspensions in a 14 L Stirred Bioreactor.

Nivelle L, Hubert J, Courot E, Jeandet P, Aziz A, Nuzillard JM, Renault JH, Clément C, Martiny L, Delmas D, Tarpin M

Molecules. 2017 Mar;22(3):

Correction: Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway.

Zeriouh W, Nani A, Belarbi M, Dumont A, de Rosny C, Aboura I, Ghanemi FZ, Murtaza B, Patoli D, Thomas C, Apetoh L, Rébé C, Delmas D, Khan NA, Ghiringhelli F, Rialland M, Hichami A

PLoS ONE. 2017 ;12(4):e0176574

Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway.

Zeriouh W, Nani A, Belarbi M, Dumont A, de Rosny C, Aboura I, Ghanemi FZ, Murtaza B, Patoli D, Thomas C, Apetoh L, Rébé C, Delmas D, Akhtar Khan N, Ghiringhelli F, Rialland M, Hichami A

PLoS ONE. 2017 ;12(2):e0170823

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX-Bevacizumab Drug Treatment Regimen.

Limagne E, Euvrard R, Thibaudin M, Rébé C, Derangère V, Chevriaux A, Boidot R, Végran F, Bonnefoy N, Vincent J, Bengrine-Lefevre L, Ladoire S, Delmas D, Apetoh L, Ghiringhelli F

Cancer Res.. 2016 Sep;76(18):5241-52

Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages.

Limagne E, Lançon A, Delmas D, Cherkaoui-Malki M, Latruffe N

Nutrients. 2016 May;8(5):

Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation.

Latruffe N, Lancon A, Frazzi R, Aires V, Delmas D, Michaille JJ, Djouadi F, Bastin J, Cherkaoui-Malki M

Ann N Y Acad Sci. 2015 Jul 17

Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7beta-hydroxycholesterol-, and 24(S)-hydroxycholesterol: Protective effects of alpha-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3).

Nury T, Zarrouk A, Mackrill JJ, Samadi M, Durand P, Riedinger JM, Doria M, Vejux A, Limagne E, Delmas D, Prost M, Moreau T, Hammami M, Delage-Mourroux R, O'Brien NM, Lizard G

Steroids. 2015 Feb 12. pii: S0039-128X(15)00059-8

Common pathways in health benefit properties of RSV in cardiovascular diseases, cancers and degenerative pathologies.

Aires V, Delmas D

Curr Pharm Biotechnol. 2015;16(3):219-44.

A role for peroxisome proliferator-activated receptor gamma in resveratrol-induced colon cancer cell apoptosis.

Aires V, Brassart B, Carlier A, Scagliarini A, Mandard S, Limagne E, Solary E, Martiny L, Tarpin M, Delmas D

Mol Nutr Food Res. 2014 Sep;58(9):1785-94

Potential role of oxidative DNA damage in the impact of PNPLA3 variant (rs 738409 C>G) in hepatocellular carcinoma risk.

Limagne E, Cottet V, Cotte AK, Hamza S, Hillon P, Latruffe N, Delmas D

Hepatology. 2014 Sep;60(3):1110-1

Differential protective effects of red wine polyphenol extracts (RWEs) on colon carcinogenesis.

Mazue F, Delmas D, Murillo G, Saleiro D, Limagne E, Latruffe N

Food Funct. 2014 Apr;5(4):663-70

Compared binding properties between resveratrol and other polyphenols to plasmatic albumin: consequences for the health protecting effect of dietary plant microcomponents.

Latruffe N, Menzel M, Delmas D, Buchet R, Lancon A

Molecules. 2014 Oct 24;19(11):17066-77

Inhibition of cancer derived cell lines proliferation by synthesized hydroxylated stilbenes and new ferrocenyl-stilbene analogs. Comparison with resveratrol.

Chalal M, Delmas D, Meunier P, Latruffe N, Vervandier-Fasseur D

Molecules. 2014 Jun 11;19(6):7850-68

Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts.

Aires V, Delmas D, Le Bachelier C, Latruffe N, Schlemmer D, Benoist JF, Djouadi F, Bastin J

Orphanet J Rare Dis. 2014 Jun 5;9:79

The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models.

Colin DJ, Limagne E, Ragot K, Lizard G, Ghiringhelli F, Solary E, Chauffert B, Latruffe N, Delmas D

Cell Death Dis. 2014 Nov 20;5:e1533

Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol.

Lin HY, Delmas D, Vang O, Hsieh TC, Lin S, Cheng GY, Chiang HL, Chen CE, Tang HY, Crawford DR, Whang-Peng J, Hwang J, Liu LF, Wu JM

J Cell Biochem. 2013 Aug;114(8):1940-54

Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes.

Ragot K, Mackrill JJ, Zarrouk A, Nury T, Aires V, Jacquin A, Athias A, Pais de Barros JP, Vejux A, Riedinger JM, Delmas D, Lizard G

Biochem Pharmacol. 2013 Jul 1;86(1):67-79

Importance of lipid microdomains, rafts, in absorption, delivery, and biological effects of resveratrol.

Delmas D, Aires V, Colin DJ, Limagne E, Scagliarini A, Cotte AK, Ghiringhelli F

Ann N Y Acad Sci. 2013 Jul;1290:90-7

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death.

Aires V, Limagne E, Cotte AK, Latruffe N, Ghiringhelli F, Delmas D

Mol Nutr Food Res. 2013 Jul;57(7):1170-81

Immunomodulation and anti-inflammatory roles of polyphenols as anticancer agents.

Ghiringhelli F, Rebe C, Hichami A, Delmas D

Anticancer Agents Med Chem. 2012 Oct 1;12(8):852-73.

Natural polyphenols properties: chemopreventive and chemosensitizing activities.

Delmas D, Xiao J

Anticancer Agents Med Chem. 2012 Oct 1;12(8):835.

A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients.

Rifler JP, Lorcerie F, Durand P, Delmas D, Ragot K, Limagne E, Mazue F, Riedinger JM, d'Athis P, Hudelot B, Prost M, Lizard G, Latruffe N

Mol Nutr Food Res. 2012 Feb;56(2):345-51

alpha-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes.

Ragot K, Delmas D, Athias A, Nury T, Baarine M, Lizard G

Chem Phys Lipids. 2011 Sep;164(6):469-78

Role of membrane dynamics processes and exogenous molecules in cellular resveratrol uptake: consequences in bioavailability and activities.

Delmas D, Lin HY

Mol Nutr Food Res. 2011 Aug;55(8):1142-53

Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.

Colin D, Limagne E, Jeanningros S, Jacquel A, Lizard G, Athias A, Gambert P, Hichami A, Latruffe N, Solary E, Delmas D

Cancer Prev Res (Phila). 2011 Jul;4(7):1095-106

Pro-apoptotic versus anti-apoptotic properties of dietary resveratrol on tumoral and normal cardiac cells.

Baarine M, Thandapilly SJ, Louis XL, Mazue F, Yu L, Delmas D, Netticadan T, Lizard G, Latruffe N

Genes Nutr. 2011 May;6(2):161-9

Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe.

Delmas D, Solary E, Latruffe N

Curr Med Chem. 2011;18(8):1100-21.

Transport, stability, and biological activity of resveratrol.

Delmas D, Aires V, Limagne E, Dutartre P, Mazué F, Ghiringhelli F, Latruffe N

Ann. N. Y. Acad. Sci.. 2011 Jan;1215:48-59

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.

Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, Das DK, Delmas D, Gottfried C, Lin HY, Ma QY, Mukhopadhyay P, Nalini N, Pezzuto JM, Richard T, Shukla Y, Surh YJ, Szekeres T, Szkudelski T, Walle T, Wu JM

PLoS One. 2011;6(6):e19881

Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFbeta signaling pathway in SW480 cells.

Tili E, Michaille JJ, Alder H, Volinia S, Delmas D, Latruffe N, Croce CM

Biochem Pharmacol. 2010 Dec 15;80(12):2057-65

Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.

Dugas B, Charbonnier S, Baarine M, Ragot K, Delmas D, Menetrier F, Lherminier J, Malvitte L, Khalfaoui T, Bron A, Creuzot-Garcher C, Latruffe N, Lizard G

Eur J Nutr. 2010 Oct;49(7):435-46