Dr ANGELOT-DELETTRE Fanny

Fiche personne

Coordonnées

EFS
8 rue du Dr Jean-François Xavier Girod
25020 BESANCON Cedex

Territoire

Franche-Comté

Statut

Hospitalier

Affiliation

Etablissement Français du Sang Bourgogne-Franche-Comté (EFS Bourgogne - Franche-Comté)

Inserm UMR 1098 "Interaction Hôte-Greffon-Tumeur, Ingénierie Cellulaire et Génique" (Inserm UMR1098 RIGHT)

Recherche

Expertises :
- Recherche:Immunologie
- Clinique:Hématologie
- Clinique:Pharmacie
- Recherche:Hématologie

Publications

Contribution of a specific panel by flow cytometry for the differential diagnosis of plasmacytoid dendritic cell neoplasms.

Renosi F, Biichlé S, Roussel X, Fournet T, Roggy A, Pourchet V, Berry JF, Fredon M, Poussard M, Asnafi V, Macintyre E, Preudhomme C, Roumier C, Deconinck E, Daguindau E, Adotévi O, Angelot-Delettre F, Garnache-Ottou F

Ann Hematol. 2026 02 17;105(4):122

Pivekimab sunirine in blastic plasmacytoid dendritic cell neoplasm: assessing spatial response and unraveling resistance mechanisms.

Poussard M, Boichut M, Belakri I, Biichle S, Fredon M, Cael B, Roussel X, Renosi F, Van Moer K, Janji B, Monnien F, Boichut C, Boidot R, Ndao B, Adotevi O, Garnache-Ottou F, Watkins K, Lakshmikanthan S, Angelot-Delettre F

Haematologica. 2026 02 5;:

Association between group B major ABO-incompatible platelet or plasma transfusion and severe allergic reactions: A nationwide haemovigilance analysis suggesting a role for α-gal syndrome. A Biomedical Excellence for Safer Transfusion Collaborative study.

Malard L, Beuscart C, de Chaisemartin L, de la Taille V, Delettre F, Humbrecht C, Dunbar N, Lecam S, Laperche S, Tiberghien P,

Vox Sang. 2025 10 29;:

Venetoclax in the Therapeutic Strategy for BPDCN Management.

Poussard M, Fredon M, Belakri I, Biichle S, Renosi F, Seffar E, Boichut M, Boidot R, Bôle-Richard E, Bonnefoy F, Kroemer M, Bonnot-Perrin S, Saas P, Adotévi O, Garnache-Ottou F, Angelot-Delettre F

EJHaem. 2025 08;6(4):e70070

ABO-mismatched platelet and plasma transfusion practices and the potential for transfusion-related alpha-gal syndrome: The Biomedical Excellence for Safer Transfusion Collaborative Study.

Dunbar NM, Kaufman RM, Bary KS, Bellairs GRM, Cohn CS, Delettre F, Ditcham S, Duarte GC, Ellison A, Fachini R, George CE, Humbrecht C, Louw V, Meier S, Morley S, Mwase M, Robitaille N, Rushford K, Sato T, Schäfer R, Staves J, Takanashi M, Tiberghien P, Wendel S, Wood EM, Ziman A, Murphy MF,

Transfusion. 2025 07 11;:

New leads to enhance tagraxofusp efficacy in pDC-AML.

Boichut M, Poussard M, Roussel X, Belakri I, Biichlé S, Fredon M, Renosi F, Boidot R, Adotevi O, Brooks C, Garnache-Ottou F, Angelot Delettre F

Blood Neoplasia. 2025 05;2(2):100066

Impact of scFv on functionality and safety of third generation CD123 CAR T cells.

Fredon M, Poussard M, Biichlé S, Bonnefoy F, Mantion CF, Seffar E, Renosi F, Bôle-Richard E, Boidot R, Chevrier S, Anna F, Loustau M, Caumartin J, Gonçalves-Venturelli M, Robinet E, Saas P, Deconinck E, Daguindau E, Roussel X, Godet Y, Adotévi O, Angelot-Delettre F, Galaine J, Garnache-Ottou F

Cancer Immunol Res. 2024 05 31;:

Conventional Therapeutics in BPDCN Patients-Do They Still Have a Place in the Era of Targeted Therapies?

Poussard M, Angelot-Delettre F, Deconinck E

Cancers (Basel). 2022 08 2;14(15):

Umbilical Cord Blood as a Source of Less Differentiated T Cells to Produce CD123 CAR-T Cells.

Caël B, Galaine J, Bardey I, Marton C, Fredon M, Biichle S, Poussard M, Godet Y, Angelot-Delettre F, Barisien C, Bésiers C, Adotevi O, Pouthier F, Garnache-Ottou F, Bôle-Richard E

Cancers (Basel). 2022 06 28;14(13):

Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis.

Togami K, Chung SS, Madan V, Booth CAG, Kenyon CM, Cabal-Hierro L, Taylor J, Kim SS, Griffin GK, Ghandi M, Li J, Li YY, Angelot-Delettre F, Biichle S, Seiler M, Buonamici S, Lovitch SB, Louissaint A, Morgan EA, Jardin F, Piccaluga PP, Weinstock DM, Hammerman PS, Yang H, Konopleva M, Pemmaraju N, Garnache-Ottou F, Abdel-Wahab O, Koeffler HP, Lane AA

Cancer Discov. 2021 Oct 6;:

Persistent COVID-19 in an immunocompromised host treated by SARS-CoV-2-specific monoclonal antibodies.

Bailly B, Péré H, Veyer D, Berceanu A, Daguindau E, Roux P, Hermine O, de Lamballerie X, Bastard P, Lacombe K, Autran B, Angelot Delettre F, Casanova JL, Imbeaud S, Clairet AL, Kroemer M, Spehner L, Robillard N, Puech J, Marty-Quinternet S, Lepiller Q, Chirouze C, Bouiller K

Clin Infect Dis. 2021 Oct 1;:

International Forum on Transfusion Practices in Haematopoietic Stem-Cell Transplantation: Responses.

Solves P, Lozano M, Zhiburt E, Anguita Velasco J, Maria Pérez-Corral A, Monsalvo-Saornil S, Yamazaki S, Okazaki H, Selleng K, Aurich K, Krüger W, Buser A, Holbro A, Infanti L, Stehle G, Pierelli L, Matteocci A, Rigacci L, De Vooght KMK, Kuball JHE, Fielding KL, Westerman DA, Wood EM, Cohn CS, Johnson A, Koh MBC, Qadir D, Cserti-Gazdewich C, Daguindau E, Angelot-Delettre F, Tiberghien P, Wendel-Neto S, Fachini RM, Morton S, Craddock C, Lumley M, Antoniewicz-Papis J, Hałaburda K, Łętowska M, Dunbar N

Vox Sang. 2021 05;116(5):e25-e43

International Forum on Transfusion Practices in Haematopoietic Stem-Cell Transplantation: Summary.

Vox Sang. 2021 05;116(5):609-612

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis.

Renosi F, Roggy A, Giguelay A, Soret L, Viailly PJ, Cheok M, Biichle S, Angelot-Delettre F, Asnafi V, Macintyre E, Geffroy S, Callanan M, Petrella T, Deconinck E, Daguindau E, Harrivel V, Bouyer S, Salaun V, Saussoy P, Feuillard J, Fuseau P, Saas P, Adotévi O, Jardin F, Ferrand C, Preudhomme C, Colinge J, Roumier C, Garnache-Ottou F

Blood Adv. 2021 Mar 9;5(5):1540-1551

BPDCN: When polychemotherapy does not compromise allogeneic CD123 CAR-T cell cytotoxicity.

Poussard M, Philippe L, Fredon M, Bôle-Richard E, Biichle S, Renosi F, Perrin S, Kroemer M, Limat S, Bonnefoy F, Daguindau E, Deconinck E, Gruson B, Saas P, Adotévi O, Garnache-Ottou F, Angelot-Delettre F

EJHaem. 2021 02;2(1):125-130

Processing methods and storage duration impact extracellular vesicle counts in red blood cell units.

Gamonet C, Desmarets M, Mourey G, Biichle S, Aupet S, Laheurte C, François A, Resch E, Bigey F, Binda D, Bardiaux L, Naegelen C, Marpaux N, Delettre FA, Saas P, Morel P, Tiberghien P, Lacroix J, Capellier G, Vidal C, Garnache-Ottou F

Blood Adv. 2020 Nov 10;4(21):5527-5539

Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape.

Zalmaï L, Viailly PJ, Biichle S, Cheok M, Soret L, Angelot-Delettre F, Petrella T, Collonge-Rame MA, Seilles E, Geffroy S, Deconinck E, Daguindau E, Bouyer S, Dindinaud E, Baunin V, Le Garff-Tavernier M, Roos-Weil D, Wagner-Ballon O, Salaun V, Feuillard J, Brun S, Drenou B, Mayeur-Rousse C, Okamba P, Dorvaux V, Tichionni M, Rose J, Rubio MT, Jacob MC, Raggueneau V, Preudhomme C, Saas P, Ferrand C, Adotevi O, Roumier C, Jardin F, Garnache-Ottou F, Renosi F

Haematologica. 2020 Oct 13;Online ahead of print:

Platelet transfusions in haematologic malignancies in the last six months of life.

Moracchini J, Seigeot A, Angelot-Delettre F, Vienot A, Aubry R, Daguindau É, Deconinck E, Frache S, Tiberghien P

Vox Sang.. 2020 Aug 13;:

CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm.

Bôle-Richard E, Fredon M, Biichlé S, Anna F, Certoux JM, Renosi F, Tsé F, Molimard C, Valmary-Degano S, Jenvrin A, Warda W, Pallandre JR, Bonnefoy F, Poussard M, Deschamps M, Petrella T, Roumier C, Macintyre E, Féger F, Brissot E, Mohty M, HoWangYin KY, Langlade-Demoyen P, Loustau M, Caumartin J, Godet Y, Binda D, Pagadoy M, Deconinck E, Daguindau E, Saas P, Ferrand C, Angelot-Delettre F, Adotévi O, Garnache-Ottou F

Leukemia. 2020 Feb 28;:

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

Garnache-Ottou F, Vidal C, Biichlé S, Renosi F, Poret E, Pagadoy M, Desmarets M, Roggy A, Seilles E, Soret L, Schillinger F, Puyraimond S, Petrella T, Preudhomme C, Roumier C, MacIntyre EA, Harrivel V, Desbrosses Y, Gruson B, Geneviève F, Thepot S, Drebit Y, Leguay T, Gros FX, Lechevalier N, Saussoy P, Salaun V, Cornet E, Benseddik Z, Veyrat-Masson R, Wagner-Ballon O, Salanoubat C, Maynadié M, Guy J, Caillot D, Jacob MC, Cahn JY, Gressin R, Rose J, Quesnel B, Guerin E, Trimoreau F, Feuillard J, Gourin MP, Plesa A, Baseggio L, Arnoux I, Vey N, Blaise D, Lacroix R, Arnoulet C, Benet B, Dorvaux V, Bret C, Drenou B, Debliquis A, Latger-Cannard V, Bonmati C, Bene MC, Peterlin P, Ticchioni M, Rohrlich PS, Arnaud A, Wickenhauser S, Bardet V, Brechignac S, Papoular B, Raggueneau V, Vargaftig J, Letestu R, Lusina D, Braun T, Foissaud V, Tamburini J, Bennani H, Freynet N, Cordonnier C, Le Garff-Tavernier M, Jacques N, Maloum K, Roos-Weil D, Bouscary D, Asnafi V, Lhermitte L, Suarez F, Lengline E, Féger F, Battipaglia G, Mohty M, Bouyer S, Ghoual O, Dindinaud E, Basle C, Puyade M, Lafon C, Fest T, Roussel M, Cahu X, Bera E, Daliphard S, Jardin F, Campos L, Solly F, Guyotat D, Galoisy AC, Eischen A, Mayeur-Rousse C, Guffroy B, Recher C, Loosveld M, Garnier A, Barlogis V, Rosenthal MA, Brun S, Contentin N, Maury S, Callanan M, Lefebvre C, Maillard N, Okamba P, Ferrand C, Adotevi O, Saas P, Angelot-Delettre F, Binda D, Deconinck E

Blood Adv. 2019 Dec 23;3(24):4238-4251

Standardization of Flow Cytometric Immunophenotyping for Hematological Malignancies: The FranceFlow Group Experience.

Solly F, Angelot-Delettre F, Ticchioni M, Geneviève F, Rambaud H, Baseggio L, Plesa A, Debliquis A, Garnache-Ottou F, Roggy A, Campos L, Aanei C, Rosenthal-Allieri A, Georget MT, Lachot S, Jacob MC, Robillard N, Wuilleme S, Andre-Kerneis E, Cornet E, Salaun V, Bennami H, Lhoumeau AC, Arnoulet C, Jacqmin H, Neyman N, Latger-Cannard V, Massin F, Lainey E, Le Garff-Tavernier M, Costopoulos M, Roussel M, Mayeur-Rousse C, Eischen A, Raggeneau V, Derrieux C, Maurer M, Asnafi V, Trinquand A, Brouzes C, Lhermitte L

Cytometry A. 2019 Jul 31;:

Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm.

Philippe L, Ceroi A, Bôle-Richard E, Jenvrin A, Biichle S, Perrin S, Limat S, Bonnefoy F, Deconinck E, Saas P, Garnache-Ottou F, Angelot-Delettre F

Haematologica. 2017 Aug;:

How to quantify microparticles in RBCs? A validated flow cytometry method allows the detection of an increase in microparticles during storage.

Gamonet C, Mourey G, Aupet S, Biichle S, Petitjean R, Vidal C, Pugin A, Naegelen C, Tiberghien P, Morel P, Angelot-Delettre F, Seilles E, Saas P, Bardiaux L, Garnache-Ottou F

Transfusion. 2017 Mar;57(3):504-516

LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis.

Ceroi A, Masson D, Roggy A, Roumier C, Chagué C, Gauthier T, Philippe L, Lamarthée B, Angelot-Delettre F, Bonnefoy F, Perruche S, Biichle S, Preudhomme C, Macintyre E, Lagrost L, Garnache-Ottou F, Saas P

Blood. 2016 Dec;128(23):2694-2707

Proteinase 3 Is a Phosphatidylserine-binding Protein That Affects the Production and Function of Microvesicles.

Martin KR, Kantari-Mimoun C, Yin M, Pederzoli-Ribeil M, Angelot-Delettre F, Ceroi A, Grauffel C, Benhamou M, Reuter N, Saas P, Frachet P, Boulanger CM, Witko-Sarsat V

J. Biol. Chem.. 2016 May;291(20):10476-89

The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation.

Ceroi A, Delettre FA, Marotel C, Gauthier T, Asgarova A, Biichlé S, Duperrier A, Mourey G, Perruche S, Lagrost L, Masson D, Saas P

Haematologica. 2016 Mar;101(3):e72-6

In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent.

Angelot-Delettre F, Roggy A, Frankel AE, Lamarthee B, Seilles E, Biichle S, Royer B, Deconinck E, Rowinsky EK, Brooks C, Bardet V, Benet B, Bennani H, Benseddik Z, Debliquis A, Lusina D, Roussel M, Solly F, Ticchioni M, Saas P, Garnache-Ottou F

Haematologica. 2015 Feb;100(2):223-30

Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients.

Frankel AE, Woo JH, Ahn C, Pemmaraju N, Medeiros BC, Carraway HE, Frankfurt O, Forman SJ, Yang XA, Konopleva M, Garnache-Ottou F, Angelot-Delettre F, Brooks C, Szarek M, Rowinsky E

Blood. 2014 Jul 17;124(3):385-92

Minimal residual disease detection of leukemic cells in ovarian cortex by eight-color flow cytometry.

Amiot C, Angelot-Delettre F, Zver T, Alvergnas-Vieille M, Saas P, Garnache-Ottou F, Roux C

Hum Reprod. 2013 Aug;28(8):2157-67

Blastic plasmacytoid dendritic cell neoplasm.

Angelot-Delettre F, Garnache-Ottou F

Blood. 2012 Oct 4;120(14):2784.

Intracytoplasmic detection of TCL1--but not ILT7-by flow cytometry is useful for blastic plasmacytoid dendritic cell leukemia diagnosis.

Angelot-Delettre F, Biichle S, Ferrand C, Seilles E, Gaugler B, Harrivel V, Rosenthal-Allieri MA, Deconinck E, Saas P, Garnache-Ottou F

Cytometry A. 2012 Aug;81(8):718-24

Correlation between platelet-derived microparticle enumeration by flow cytometry and phospholipid-dependent procoagulant activity in microparticles: the centrifugation step matters!

Stagnara J, Garnache Ottou F, Angelot F, Mourey G, Seilles E, Biichle S, Saas P, Racadot E

Thromb Haemost. 2012 Jun;107(6):1185-7

Phosphatidylserine-expressing cell by-products in transfusion: A pro-inflammatory or an anti-inflammatory effect?

Saas P, Angelot F, Bardiaux L, Seilles E, Garnache-Ottou F, Perruche S

Transfus Clin Biol. 2012 Jun;19(3):90-7

CD304 is preferentially expressed on a subset of B-lineage acute lymphoblastic leukemia and represents a novel marker for minimal residual disease detection by flow cytometry.

Solly F, Angelot F, Garand R, Ferrand C, Seillès E, Schillinger F, Decobecq A, Billot M, Larosa F, Plouvier E, Deconinck E, Legrand F, Saas P, Rohrlich PS, Garnache-Ottou F

Cytometry A. 2012 Jan;81(1):17-24