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Bone health in Parkinson's disease: a comprehensive review of bone involvement and its pathophysiological mechanisms.

Toussirot E, Compagne C, Vauchy C, Bereau M

Front Med (Lausanne). 2026 01 13;12:1737844

Editorial: Community series in recent advances in potential biomarkers for rheumatic diseases and in cell-based therapies in the management of inflammatory rheumatic diseases, volume III.

Toussirot E, Bogunia-Kubik K, Saas P

Front Immunol. 2026 01 6;16:1771049

Citrullinated peptides of peptidyl arginine deiminase 4 as major B-cell epitopes in patients with rheumatoid arthritis.

Giassi M, Toussirot E, Lambert NC, Roudier J, Auger I

Front Immunol. 2025 09 2;16:1640291

Analysis of gut homing receptors in circulating MAIT cells and their presence in synovial tissue from patients with axial spondyloarthritis.

Toussirot É, Ramon A, Laheurte C, Gravelin E, Vauchy C, Monnien F, Puyraveau M, Samson M, Saas P

J Rheumatol. 2025 05 15;:

Maintenance of remission after tocilizumab withdrawal in patients with glucocorticoid-dependent polymyalgia rheumatica.

Chevet B, Souki A, Nowak E, Carvajal-Alegria G, Dernis E, Richez C, Truchetet ME, Wendling D, Toussirot E, Perdriger A, Gottenberg JE, Felten R, Fautrel B, Lohse A, Chiche L, Hilliquin P, Le Henaff C, Dervieux B, Direz G, Chary-Valckenaere I, Cornec D, Guellec D, Marhadour T, Saraux A, Devauchelle-Pensec V

Arthritis Rheumatol. 2025 05 7;:

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19: an international, randomised, open-label trial.

Hoffmann S, Schrezenmeier E, Desmarets M, Halleck F, Durrbach A, Peters L, Tremmel AT, Seidel A, Führer M, Bachmann F, Schrezenmeier J, Greiner J, Körper S, Hofmann H, Ludwig C, Vieweg C, Jahrsdörfer B, Budde K, Schmidt M, Münch J, Joher N, Daguindau E, Grüner B, Brunotte G, Vauchy C, Seifried E, Bradshaw D, Estcourt LJ, Roberts DJ, Toussirot E, Rijnders B, Tiberghien P, Schrezenmeier H

EBioMedicine. 2025 02 27;113:105613

Editorial: Community series in recent advances in potential biomarkers for rheumatic diseases and in cell-based therapies in the management of inflammatory rheumatic diseases, volume II.

Bogunia-Kubik K, Saas P, Toussirot E

Front Immunol. 2025 01 3;15:1530739

IL-17 inhibitors in axial spondyloarthritis. An overview.

Toussirot E, Felten R

Expert Opin Biol Ther. 2024 08 17;:

Concordance and agreement between different activity scores in polymyalgia rheumatica.

D'Agostino J, Souki A, Lohse A, Carvajal Alegria G, Dernis E, Richez C, Truchetet ME, Wendling D, Toussirot E, Perdriger A, Gottenberg JE, Felten R, Fautrel B, Chiche L, Hilliquin P, Le Henaff C, Dervieux B, Direz G, Chary-Valckenaere I, Cornec D, Guellec D, Marhadour T, Nowak E, Saraux A, Devauchelle-Pensec V

RMD Open. 2024 03 15;10(1):

Areal bone mineral density, trabecular bone score and 3D-DXA analysis of proximal femur in psoriatic disease.

Toussirot E, Winzenrieth R, Aubin F, Wendling D, Vauchy C, Desmarets M

Front Med (Lausanne). 2024 01 30;11:1341077

Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients.

Felten R, Toussirot E

Drugs Aging. 2023 10 30;:

Editorial: Impact and consequences of COVID-19 on the musculoskeletal system.

Toussirot E, Maglio M, Fini M, Salamanna F

Front Med (Lausanne). 2023 09 22;10:1288778

Evolution of monoclonal gammopathy of undetermined significance in patients treated with JAK inhibitors for rheumatic diseases: data from the MAJIK-SFR registry.

Faganello D, Bertrand A, Meunier P, Avouac J, Toussirot E, Coury F, Seror R, Le Mélédo G, Germain V, Dellal A, Shima D, Hulin C, Prati C, Schaeverbeke T, Richez C, Truchetet ME, Kostine M

Rheumatology (Oxford). 2023 08 4;:

ATHLETIQUE: interest of an adapted physical activity program in patients with juvenile idiopathic arthritis: a feasibility and preliminary effectiveness study.

Py S, Maylié F, Parmentier AL, Vidal C, Cuinet B, Mauny F, Lohse A, Toussirot E, Yoshimasa S, Tordi N, Binda D, Ballot-Schmit C

Front Immunol. 2023 06 27;14:1213799

Advances in pharmacotherapies for axial spondyloarthritis.

Toussirot E

Expert Opin Pharmacother. 2023 06 15;:

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial.

Desmarets M, Hoffmann S, Vauchy C, Rijnders BJA, Toussirot E, Durrbach A, Körper S, Schrezenmeier E, van der Schoot CE, Harvala H, Brunotte G, Appl T, Seifried E, Tiberghien P, Bradshaw D, Roberts DJ, Estcourt LJ, Schrezenmeier H

BMJ Open. 2023 04 27;13(4):e071277

The Influence of Adipokines on Radiographic Damage in Inflammatory Rheumatic Diseases.

Toussirot E

Biomedicines. 2023 02 13;11(2):

Fractures reduction with osteoporotic treatments in patients over 75-year-old: A systematic review and meta-analysis.

Guillaumin M, Poirson B, Gerazime A, Puyraveau M, Tannou T, Mauny F, Toussirot É

Front Aging. 2022 11 2;3:845886

Effect of Tocilizumab on Disease Activity in Patients With Active Polymyalgia Rheumatica Receiving Glucocorticoid Therapy: A Randomized Clinical Trial.

Devauchelle-Pensec V, Carvajal-Alegria G, Dernis E, Richez C, Truchetet ME, Wendling D, Toussirot E, Perdriger A, Gottenberg JE, Felten R, Fautrel BJ, Chiche L, Hilliquin P, Le Henaff C, Dervieux B, Direz G, Chary-Valckenaere I, Cornec D, Guellec D, Marhadour T, Nowak E, Saraux A

JAMA. 2022 09 20;328(11):1053-1062

The cardiometabolic conditions of psoriatic disease.

Toussirot E, Gallais-Sérézal I, Aubin F

Front Immunol. 2022 09 8;13:970371

Lack of association between the TNFAIP3 rs2230926 variant and rheumatoid arthritis-associated lymphoma.

Kedra J, Seror R, Dieudé P, Constantin A, Toussirot E, Kfoury E, Masson C, Cornec D, Dubost JJ, Marguerie L, Ottaviani S, Grados F, Belkhir R, Fain O, Fautrel B, Philippe P, Piperno M, Combe B, Lambotte O, Richez C, Sellam J, Sené T, Denis G, Lequerre T, Lazure T, Mariette X, Nocturne G

Joint Bone Spine. 2022 Apr 28;:105390

The Use of Janus Kinase Inhibitors in Axial Spondyloarthritis: Current Insights.

Toussirot E

Pharmaceuticals (Basel). 2022 Feb 22;15(3):

Abatacept as Adjunctive Therapy in Refractory Polymyalgia Rheumatica.

Toussirot E, Michaud M, Wendling D, Devauchelle V

J Rheumatol. 2021 Sep 15;:

Lymphoma complicating rheumatoid arthritis: results from a French case-control study.

Kedra J, Seror R, Dieudé P, Constantin A, Toussirot E, Kfoury E, Masson C, Cornec D, Dubost JJ, Marguerie L, Ottaviani S, Grados F, Belkhir R, Fain O, Goupille P, Sordet C, Fautrel B, Philippe P, Piperno M, Combe B, Lambotte O, Richez C, Sellam J, Sené T, Denis G, Lequerre T, Lazure T, Mariette X, Nocturne G

RMD Open. 2021 09;7(3):

Convalescent plasma to treat COVID-19: Following the Argentinian lead.

Tiberghien P, Toussirot E, Richard P, Morel P, Garraud O

Transfus Apher Sci. 2021 06;60(3):103161

Editorial: Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-Based Therapies in the Management of Inflammatory Rheumatic Diseases.

Saas P, Toussirot E, Bogunia-Kubik K

Front Immunol. 2021 ;12:836119

Mini-Review: The Administration of Apoptotic Cells for Treating Rheumatoid Arthritis: Current Knowledge and Clinical Perspectives.

Toussirot E, Bonnefoy F, Vauchy C, Perruche S, Saas P

Front Immunol. 2021 ;12:630170

The Risk of Cardiovascular Diseases in Axial Spondyloarthritis. Current Insights.

Toussirot E

Front Med (Lausanne). 2021 ;8:782150

Visceral adiposity in patients with psoriatic arthritis and psoriasis alone and its relationship with metabolic and cardiovascular risk.

Toussirot E, Aubin F, Desmarets M, Wendling D, Augé B, Gillard J, Messica O, Guillot X, Laheurte C, Monnet E, Dumoulin G

Rheumatology (Oxford). 2020 Nov 24;:

Sustained remission of ankylosing spondylitis following intravesical Bacillus Calmette et Guérin immunotherapy for bladder cancer.

Toussirot E, Guichard G, Saas P

Clin Exp Rheumatol. 2020 Nov 22;:

Rituximab for rheumatoid arthritis-associated large granular lymphocytic leukemia, a retrospective case series.

Lobbes H, Dervout C, Toussirot E, Felten R, Sibilia J, Wendling D, Gombert B, Ruivard M, Grobost V, Saraux A, Cornec D, Verhoeven F, Soubrier M

Semin Arthritis Rheum. 2020 10;50(5):1109-1113

Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study.

Toussirot E, Marotte H, Mulleman D, Cormier G, Coury F, Gaudin P, Dernis E, Bonnet C, Damade R, Grauer JL, Abdesselam TA, Guillibert-Karras C, Lioté F, Hilliquin P, Sacchi A, Wendling D, Le Goff B, Puyraveau M, Dumoulin G

Arthritis Res Ther. 2020 09 29;22(1):224

Tocilizumab failure in malignancy-related polymyalgia rheumatica.

Toussirot E, Govindaraju S, Mekinian A

Joint Bone Spine. 2020 07;87(4):366-368

L5 Radiculopathy with Neurological Deficit Due To Sacral Insufficiency Fracture.

Toussirot E, Bereau M, Aubry S

J Rheumatol. 2020 06 1;47(6):939-940

Spondyloarthritis-Associated IgA Nephropathy.

Champtiaux N, Lioté F, El Karoui K, Vigneau C, Miceli C, Cornec-Le Gall E, Rémy P, Choukroun G, Fakhouri F, Garrouste C, Veillon L, Pillebout E, Lobbedez T, Vuiblet V, Wynckel A, Guincestre T, Toussirot E, Thervet E, Rabant M, Karras A

Kidney Int Rep. 2020 Jun;5(6):813-820

An unusual association of CANOMAD and rheumatoid arthritis with a long-term follow-up.

Toussirot E, Bereau M, Sevrin P, Tatu L

Joint Bone Spine. 2020 05;87(3):263-264

The Interrelations between Biological and Targeted Synthetic Agents Used in Inflammatory Joint Diseases, and Obesity or Body Composition.

Toussirot E

Metabolites. 2020 Mar 13;10(3):

Mini-Review: The Contribution of Adipokines to Joint Inflammation in Inflammatory Rheumatic Diseases.

Toussirot E

Front Endocrinol (Lausanne). 2020 ;11:606560

Pharmacological management of axial spondyloarthritis in adults.

Toussirot E

Expert Opin Pharmacother. 2019 Aug;20(12):1483-1491

Anti-neutrophil cytoplasmic antibody-associated chronic inflammatory arthritis without vasculitis. Data from a French nationwide survey.

Carvajal Alegria G, Groh M, Guellec D, Toussirot E, Rigaud J, Soubrier M, Ottaviani S, Direz G, Saraux A, Cornec D,

Autoimmun Rev. 2018 12;17(12):1268-1269

Unilateral Accessory Sacroiliac Joint with Bone Marrow Edema Mimicking Sacroiliitis.

Toussirot E, Aubry S, Runge M

J Rheumatol. 2018 08;45(9):1327-1328

Could Sodium Chloride be an Environmental Trigger for Immune-Mediated Diseases? An Overview of the Experimental and Clinical Evidence.

Toussirot E, Béreau M, Vauchy C, Saas P

Front Physiol. 2018 ;9:440

Increased IL-22- and IL-17A-Producing Mucosal-Associated Invariant T Cells in the Peripheral Blood of Patients With Ankylosing Spondylitis.

Toussirot É, Laheurte C, Gaugler B, Gabriel D, Saas P

Front Immunol. 2018 ;9:1610

Ixekizumab: an anti- IL-17A monoclonal antibody for the treatment of psoriatic arthritis.

Toussirot E

Expert Opin Biol Ther. 2018 01;18(1):101-107

MAIT cells: potent major cellular players in the IL-17 pathway of spondyloarthritis?

Toussirot E, Saas P

RMD Open. 2018 ;4(2):e000821

Biologics in myelodysplastic syndrome-related systemic inflammatory and autoimmune diseases: French multicenter retrospective study of 29 patients.

Mekinian A, Dervin G, Lapidus N, Kahn JE, Terriou L, Liozon E, Grignano E, Piette JC, Rauzy OB, Grobost V, Godmer P, Gillard J, Rossignol J, Launay D, Aouba A, Cardon T, Bouillet L, Broner J, Vinit J, Ades L, Carrat F, Salvado C, Toussirot E, Versini M, Costedoat-Chalumeau N, Fraison JB, Guilpain P, Fenaux P, Fain O,

Autoimmun Rev. 2017 Sep;16(9):903-910

Paradoxical elevation of serum TRACP5b levels despite increase in lumbar spine bone mineral density during anti-TNFα therapy in patients with inflammatory rheumatic disease: a 2-year prospective assessment of bone mass, bone metabolism, and the trabecular

Toussirot É, Mourot L, Dehecq B, Michel F, Wendling D, Grandclément É, Dumoulin G

Eur J Rheumatol. 2017 Sep;4(3):189-193

Serum adipokines, adipose tissue measurements and metabolic parameters in patients with advanced radiographic knee osteoarthritis.

Toussirot E, Michel F, Béreau M, Dehecq B, Gaugler B, Wendling D, Grandclément E, Saas P, Dumoulin G

Clin. Rheumatol.. 2017 Aug;:

New treatment options and emerging drugs for axial spondyloarthritis: biological and targeted synthetic agents.

Toussirot E

Expert Opin Pharmacother. 2017 Feb;18(3):275-282

Harnessing Apoptotic Cell Clearance to Treat Autoimmune Arthritis.

Saas P, Bonnefoy F, Toussirot E, Perruche S

Front Immunol. 2017 ;8:1191

New-onset vitiligo and progression of pre-existing vitiligo during treatment with biological agents in chronic inflammatory diseases.

Méry-Bossard L, Bagny K, Chaby G, Khemis A, Maccari F, Marotte H, Perrot JL, Reguiai Z, Sigal ML, Avenel-Audran M, Boyé T, Grasland A, Gillard J, Jullien D, Toussirot E

J Eur Acad Dermatol Venereol. 2017 Jan;31(1):181-186

Switching from originator biological agents to biosimilars: what is the evidence and what are the issues?

Toussirot E, Marotte H

RMD Open. 2017 ;3(2):e000492

Apoptotic cell infusion treats ongoing collagen-induced arthritis, even in the presence of methotrexate, and is synergic with anti-TNF therapy.

Bonnefoy F, Daoui A, Valmary-Degano S, Toussirot E, Saas P, Perruche S

Arthritis Res. Ther.. 2016 Aug;18(1):184

Multiple paradoxical adverse events in a patient with ankylosing spondylitis treated with adalimumab.

Toussirot É, Charollais R, Aubin F

Eur J Dermatol. 2016 Aug;26(4):406-8

Tocilizumab in Giant Cell Arteritis: A Multicenter Retrospective Study of 34 Patients.

Régent A, Redeker S, Deroux A, Kieffer P, Ly KH, Dougados M, Liozon E, Larroche C, Guillevin L, Bouillet L, Espitia O, Costedoat-Chalumeau N, Soubrier M, Brihaye B, Lifermann F, Lefevre G, Puéchal X, Mouthon L, Toussirot E,

J Rheumatol. 2016 08;43(8):1547-52

Hidradenitis suppurativa (HS): An unrecognized paradoxical effect of biologic agents (BA) used in chronic inflammatory diseases.

Faivre C, Villani AP, Aubin F, Lipsker D, Bottaro M, Cohen JD, Durupt F, Jeudy G, Sbidian E, Toussirot E, Badot V, Barbarot S, Debarbieux S, Delaporte E, Goegebeur G, Morel J, Nassif A, Duru G, Jullien D,

J. Am. Acad. Dermatol.. 2016 Jun;74(6):1153-9

Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study.

Mekinian A, Grignano E, Braun T, Decaux O, Liozon E, Costedoat-Chalumeau N, Kahn JE, Hamidou M, Park S, Puéchal X, Toussirot E, Falgarone G, Launay D, Morel N, Trouiller S, Mathian A, Gombert B, Schoindre Y, Lioger B, De Wazieres B, Amoura Z, Buchdaul AL, Georgin-Lavialle S, Dion J, Madaule S, Raffray L, Cathebras P, Piette JC, Rose C, Ziza JM, Lortholary O, Montestruc F, Omouri M, Denis G, Rossignol J, Nimubona S, Adès L, Gardin C, Fenaux P, Fain O

Rheumatology (Oxford). 2016 Feb;55(2):291-300

Golimumab in radiographic and nonradiographic axial spondyloarthritis: a review of clinical trials.

Toussirot E, Vauchy C, Binda D, Michel F

Drug Des Devel Ther. 2016 ;10:2087-94

Interleukin-6: a promising target for the treatment of polymyalgia rheumatica or giant cell arteritis?

Toussirot É, Régent A, Devauchelle-Pensec V, Saraux A, Puéchal X

RMD Open. 2016 ;2(2):e000305

Paradoxical reactions under TNF-α blocking agents and other biological agents given for chronic immune-mediated diseases: an analytical and comprehensive overview.

Toussirot É, Aubin F

RMD Open. 2016 ;2(2):e000239

Rapid and Sustained Response to Tocilizumab in Patients with Polymyalgia Rheumatica Resistant or Intolerant to Glucocorticoids: A Multicenter Open-label Study.

Toussirot É, Martin A, Soubrier M, Redeker S, Régent A

J Rheumatol. 2016 Jan;43(1):249-50

Dysphagia Related to Esophagus Compression by Anterior Cervical Ossification in a Patient with Ankylosing Spondylitis.

Toussirot É, Mauvais O, Aubry S

J Rheumatol. 2015 Oct;42(10):1922-3

The alternative CD20 transcript variant is not a surrogate marker for resistance to rituximab in patients with rheumatoid arthritis.

Gamonet C, Deschamps M, Marion S, Herbein G, Chiocchia G, Auger I, Saas P, Ferrand C, Toussirot E

Rheumatology (Oxford). 2015 Sep;54(9):1744-5

Diagnosis and Management of Late-Onset Spondyloarthritis: Implications of Treat-to-Target Recommendations.

Toussirot É

Drugs Aging. 2015 Jul;32(7):515-24

Sirt-1 activity in PBMC from patients with spondyloarthritis.

Wendling D, Delattre E, Abbas W, Guillot X, Toussirot E, Herbein G

Joint Bone Spine. 2015 May;82(3):210-1

The role of leptin in the pathophysiology of rheumatoid arthritis.

Toussirot E, Michel F, Binda D, Dumoulin G

Life Sci. 2015 May 26. pii: S0024-3205(15)00257-X

Effects of TNFα inhibitors on adiposity and other cardiovascular risk factors: implications for the cardiovascular prognosis in patients with rheumatoid arthritis.

Toussirot É

Expert Opin Drug Saf. 2015 Apr;14(4):525-32

Biologics in spondyloarthritis: TNFα inhibitors and other agents.

Toussirot É

Immunotherapy. 2015 ;7(6):669-81

Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.

Wendling D, Abbas W, Godfrin-Valnet M, Kumar A, Guillot X, Khan KA, Vidon C, Coquard L, Toussirot E, Prati C, Herbein G

PLoS ONE. 2015 ;10(3):e0119981

New CD20 alternative splice variants: molecular identification and differential expression within hematological B cell malignancies.

Gamonet C, Bole-Richard E, Delherme A, Aubin F, Toussirot E, Garnache-Ottou F, Godet Y, Ysebaert L, Tournilhac O, Caroline D, Larosa F, Deconinck E, Saas P, Borg C, Deschamps M, Ferrand C

Exp Hematol Oncol. 2015 ;5:7

Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner.

Toussirot É, Michel F, Meneveau N

Case Rep Rheumatol. 2015 ;2015:721078

Vaccination and Induction of Autoimmune Diseases.

Toussirot É, Bereau M

Inflamm Allergy Drug Targets. 2015 ;14(2):94-8

Association of mastocytosis with inflammatory joint diseases: a series of 31 patients.

Bader-Meunier B, Bulai Livideanu C, Larroche C, Durieu I, Artru L, Beucher A, Cormier G, Cornec D, Delarco M, Dubost JJ, Fontaine C, Gourin MP, Javier RM, de Jauréguiberry JP, Maisonneuve H, Toussirot E, Ugo V, Echaubard S, Mahlaoui N, Aouba A, Bodemer C, Briot K, Frenzel L, Lortholary O, Chandesris MO, Hermine O,

Semin Arthritis Rheum. 2014 Dec;44(3):362-5