Détail - canceropole-wordpress

HDV sensing drives USP18-mediated refractoriness to IFN-α response, sparing IFN-β/λ in hepatocytes.

Eber C, Fouillé R, Moehlin J, Juehling F, Casetta P, Chabot E, Bach C, Schuster C, Baumert TF, Lupberger J, Durantel D, Lucifora J, Verrier ER

Antiviral Res. 2026 03 13;:106395

The complex interplay between hepatitis D virus and the interferon response.

Eber C, Verrier ER

Biomed J. 2026 03 7;:100964

Hepatitis B virus-infected hepatocytes promote the secretion of collagen VI to the extracellular matrix.

Virzì A, Boulahtouf Z, Moehlin J, Girard L, Meiss-Heydmann L, Bach C, Gerges E, Durand SC, Oudot MA, Roca Suarez AA, Popp O, Ramberger E, Mertins P, Felli E, Pessaux P, Schuster C, Verrier ER, Baumert TF, Lupberger J

Sci Rep. 2025 07 10;15(1):24949

Clinical Trials for Hepatitis Delta Virus in the WHO African region: A neglected virus among neglected viruses.

Delphin M, Campbell J, Verrier ER, Anderson M, Sukali G, Maponga T, Stockdale A, Matthews PC

J Infect. 2025 05 21;:106514

Virology special issue: Hepatitis B.

Tu T, Verrier ER, Testoni B

Virology. 2025 05 15;:110550

A novel system for simultaneous infections with hepatitis B, C, D and E viruses.

Fouillé R, Verrier ER, De Meyer A, Verhoye L, Michelet M, Barnault R, Pons C, Diaz O, Rivoire M, Passot G, Steinmann E, Wedemeyer H, Salvetti A, Pavio N, Doceul V, Darteil R, Meuleman P, Durantel D, Lucifora J

JHEP Rep. 2025 05;7(5):101383

Hijacking JAKis: JAK inhibitors as potential antiviral molecules, a mini review.

Eber C, Verrier ER

Antiviral Res. 2025 03 27;:106153

[Deciphering the links between hepatic viruses and interferons: molecular interactions and therapeutic implications].

Authier C, Eber C, Fouillé R, Lucifora J, Verrier ER

Virologie (Montrouge). 2025 02 1;29(1):19-39

[Non-alphabetic viral hepatitis].

Pastor F, Delphin M, Lucifora J, Verrier ER

Med Sci (Paris). 2025 02;41(2):145-153

CAM-A-dependent HBV core aggregation induces apoptosis through ANXA1.

Taverniti V, Meiss-Heydmann L, Gadenne C, Vanrusselt H, Kum DB, Giannone F, Pessaux P, Schuster C, Baumert TF, Debing Y, Verrier ER

JHEP Rep. 2024 10;6(10):101134

Major open questions in the hepatitis B and D field - Proceedings of the inaugural International emerging hepatitis B and hepatitis D researchers workshop.

Tu T, Wettengel J, Xia Y, Testoni B, Littlejohn M, Le Bert N, Ebert G, Verrier ER, Tavis JE, Cohen C

Virology. 2024 04 16;595:110089

Comparative analysis of human, rodent and snake deltavirus replication.

Khalfi P, Denis Z, McKellar J, Merolla G, Chavey C, Ursic-Bedoya J, Soppa L, Szirovicza L, Hetzel U, Dufourt J, Leyrat C, Goldmann N, Goto K, Verrier E, Baumert TF, Glebe D, Courgnaud V, Gregoire D, Hepojoki J, Majzoub K

PLoS Pathog. 2024 03 5;20(3):e1012060

JAK1 promotes HDV replication and is a potential target for antiviral therapy.

Heuschkel MJ, Bach C, Meiss-Heydmann L, Gerges E, Felli E, Giannone F, Pessaux P, Schuster C, Lucifora J, Baumert TF, Verrier ER

J Hepatol. 2023 11 2;:

Novel non-HAP class A HBV capsid assembly modulators have distinct and profiles.

Vanrusselt H, Kum DB, Taverniti V, Liu C, Acosta Sanchez A, Corthout N, Munck S, Baumert TF, Beigelman L, Blatt LM, Symons JA, Deval J, Raboisson P, Verrier ER, Jekle A, Vendeville S, Debing Y

J Virol. 2023 09 27;:e0072223

Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.

Kum DB, Vanrusselt H, Acosta Sanchez A, Taverniti V, Verrier ER, Baumert TF, Liu C, Deval J, Corthout N, Munck S, Beigelman L, Blatt LM, Symons JA, Raboisson P, Jekle A, Vendeville S, Debing Y

Hepatology. 2023 04 28;:

Polymorphisms within DIO2 and GADD45A genes increase the risk of liver disease progression in chronic hepatitis b carriers.

Rybicka M, Verrier ER, Baumert TF, Bielawski KP

Sci Rep. 2023 04 14;13(1):6124

Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and -independent mechanisms.

Lucifora J, Alfaiate D, Pons C, Michelet M, Ramirez R, Fusil F, Amirache F, Rossi A, Legrand AF, Charles E, Vegna S, Farhat R, Rivoire M, Passot G, Gadot N, Testoni B, Bach C, Baumert TF, Hyrina A, Beran RK, Zoulim F, Boonstra A, Büning H, Verrier ER, Cosset FL, Fletcher SP, Salvetti A, Durantel D

J Hepatol. 2023 01 23;:

Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target.

Verrier ER, Ligat G, Heydmann L, Doernbrack K, Miller J, Maglott-Roth A, Jühling F, El Saghire H, Heuschkel MJ, Fujiwara N, Hsieh SY, Hoshida Y, Root DE, Felli E, Pessaux P, Mukherji A, Mailly L, Schuster C, Brino L, Nassal M, Baumert TF

Gut. 2022 12 9;:

A stable hepatitis D virus-producing cell line for host target and drug discovery.

Bach C, Lucifora J, Delphin M, Heydmann L, Heuschkel MJ, Pons C, Goto K, Scheers E, Schuster C, Durantel D, Pauwels F, Baumert TF, Verrier ER

Antiviral Res. 2022 11 26;209:105477

[Hepatitis B virus receptor: Structure and clinical implications].

Verrier ÉR

Med Sci (Paris). 2022 11;38(11):867-869

Inhibiting cell-to-cell transmission to reach HDV cure: the importance of IFNα.

Lucifora J, Verrier ER, Baumert TF

J Hepatol. 2022 08 8;:

Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences.

Boulahtouf Z, Virzì A, Baumert TF, Verrier ER, Lupberger J

Int J Mol Sci. 2022 Mar 3;23(5):

Capsid Assembly Modulators as Antiviral Agents against HBV: Molecular Mechanisms and Clinical Perspectives.

Taverniti V, Ligat G, Debing Y, Kum DB, Baumert TF, Verrier ER

J Clin Med. 2022 Mar 1;11(5):

Loss of hepatitis D virus infectivity upon farnesyl transferase inhibitor treatment associates with increasing RNA editing rates revealed by a new RT-ddPCR method.

Verrier ER, Salvetti A, Pons C, Michelet M, Rivoire M, Baumert TF, Durantel D, Lucifora J

Antiviral Res. 2022 Jan 17;198:105250

A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.

Crouchet E, Bandiera S, Fujiwara N, Li S, El Saghire H, Fernández-Vaquero M, Riedl T, Sun X, Hirschfield H, Jühling F, Zhu S, Roehlen N, Ponsolles C, Heydmann L, Saviano A, Qian T, Venkatesh A, Lupberger J, Verrier ER, Sojoodi M, Oudot MA, Duong FHT, Masia R, Wei L, Thumann C, Durand SC, González-Motos V, Heide D, Hetzer J, Nakagawa S, Ono A, Song WM, Higashi T, Sanchez R, Kim RS, Bian CB, Kiani K, Croonenborghs T, Subramanian A, Chung RT, Straub BK, Schuppan D, Ankavay M, Cocquerel L, Schaeffer E, Goossens N, Koh AP, Mahajan M, Nair VD, Gunasekaran G, Schwartz ME, Bardeesy N, Shalek AK, Rozenblatt-Rosen O, Regev A, Felli E, Pessaux P, Tanabe KK, Heikenwälder M, Schuster C, Pochet N, Zeisel MB, Fuchs BC, Hoshida Y, Baumert TF

Nat Commun. 2021 Sep 17;12(1):5525

Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinoma.

Jühling F, Saviano A, Ponsolles C, Heydmann L, Crouchet E, Durand SC, El Saghire H, Felli E, Lindner V, Pessaux P, Pochet N, Schuster C, Verrier ER, Baumert TF

Life Sci Alliance. 2021 Sep;4(9):

Cell Culture Models for the Study of Hepatitis D Virus Entry and Infection.

Heuschkel MJ, Baumert TF, Verrier ER

Viruses. 2021 Aug 3;13(8):

[Jet virology: analysis of scientific publications during pandemics].

Verrier ER

Virologie (Montrouge). 2021 Jun 17;:

Hepatitis B virus-host interactions and novel targets for viral cure.

Ligat G, Verrier ER, Nassal M, Baumert TF

Curr Opin Virol. 2021 May 21;49:41-51

Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing.

Verrier ER, Langevin C

Front Immunol. 2021 ;12:637399

Editorial: Nucleic Acid-Associated Inflammation.

Laguette N, Langevin C, Olagnier D, Torraca V, Vanpouille-Box C, Verrier ER

Front Immunol. 2021 ;12:791580

Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes.

Rybicka M, Woziwodzka A, Sznarkowska A, Romanowski T, Stalke P, Dręczewski M, Verrier ER, Baumert TF, Bielawski KP

Cancers (Basel). 2020 Nov 7;12(11):

Targeting Viral cccDNA for Cure of Chronic Hepatitis B.

Ligat G, Goto K, Verrier E, Baumert TF

Curr Hepatol Rep. 2020 09;19(3):235-244

A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor.

Eller C, Heydmann L, Colpitts CC, El Saghire H, Piccioni F, Jühling F, Majzoub K, Pons C, Bach C, Lucifora J, Lupberger J, Nassal M, Cowley GS, Fujiwara N, Hsieh SY, Hoshida Y, Felli E, Pessaux P, Sureau C, Schuster C, Root DE, Verrier ER, Baumert TF

Nat Commun. 2020 Jun 1;11(1):2707

Genetic variation in IL-10 influences the progression of hepatitis B infection.

Rybicka M, Woziwodzka A, Sznarkowska A, Romanowski T, Stalke P, Dręczewski M, Verrier ER, Baumert TF, Bielawski KP

Int. J. Infect. Dis.. 2020 May 6;:

Targeting the Host for New Therapeutic Perspectives in Hepatitis D.

Turon-Lagot V, Saviano A, Schuster C, Baumert TF, Verrier ER

J Clin Med. 2020 Jan 14;9(1):

Hepatitis D Virus Infection Revisited.

Verrier ER, Majzoub K, Baumert TF

Gastroenterology. 2019 Oct 3;:

Hepatitis D virus: viral cycle and new therapeutic approaches.

Turon-Lagot V, Saviano A, Schuster C, Verrier ÉR

Virologie (Montrouge). 2019 06 1;23(3):149-159

Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development.

Lupberger J, Croonenborghs T, Roca Suarez AA, Van Renne N, Jühling F, Oudot MA, Virzì A, Bandiera S, Jamey C, Meszaros G, Brumaru D, Mukherji A, Durand SC, Heydmann L, Verrier ER, El Saghire H, Hamdane N, Bartenschlager R, Fereshetian S, Ramberger E, Sinha R, Nabian M, Everaert C, Jovanovic M, Mertins P, Carr SA, Chayama K, Dali-Youcef N, Ricci R, Bardeesy NM, Fujiwara N, Gevaert O, Zeisel MB, Hoshida Y, Pochet N, Baumert TF

Gastroenterology. 2019 Apr 9;:

Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets.

Verrier ER, Weiss A, Bach C, Heydmann L, Turon-Lagot V, Kopp A, El Saghire H, Crouchet E, Pessaux P, Garcia T, Pale P, Zeisel MB, Sureau C, Schuster C, Brino L, Baumert TF

Gut. 2019 Mar 4;:

The functional role of sodium taurocholate cotransporting polypeptide NTCP in the life cycle of hepatitis B, C and D viruses.

Eller C, Heydmann L, Colpitts CC, Verrier ER, Schuster C, Baumert TF

Cell. Mol. Life Sci.. 2018 Nov;75(21):3895-3905

Genetic and transcriptomic analyses provide new insights on the early antiviral response to VHSV in resistant and susceptible rainbow trout.

Verrier ER, Genet C, Laloë D, Jaffrezic F, Rau A, Esquerre D, Dechamp N, Ciobotaru C, Hervet C, Krieg F, Jouneau L, Klopp C, Quillet E, Boudinot P

BMC Genomics. 2018 Jun 19;19(1):482

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