Dr NOMINE Yves

Fiche personne

Coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH

03 69 48 52 30

Territoire

Alsace

Statut

Enseignant-Chercheur

Affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

Équipes/plateformes

Equipe "Biologie structurale intégrative / Oncoprotéines virales et réseaux domaines-motifs"

Projets

Etude des interactions entre oncoprotéines virales et domaines PDZ selon une approche INteractomique QUANTitative : implications pour le cancer (InQuant)

2018 - Porteur du projet : Dr NOMINE Yves

Publications

Pharmacological inhibition of UBASH3B induces mitotic arrest and selectively reduces tumor growth.

Pangou E, Awal S, Meode M, Kleiss C, Cloarec M, Grandgirard E, Vivot K, Guerber L, Krupina K, Jerabkova-Roda K, Costa PJD, Alpy F, Martinet A, Lodi M, Cousido-Siah A, Wendling O, Hany R, Riché S, Daubeuf F, Gizzi P, Villa P, Nominé Y, Tomasetto C, Bonnet D, Sumara I

EMBO Mol Med. 2026 09 22;:

Distinct Molten-Globule Conformations in an Interacting Protein Domain Resolved by F NMR of Fluoroproline Residues.

Bouzayene AB, Sai M, Jouin A, Nominé Y, Torbeev V, Kieffer B

Angew Chem Int Ed Engl. 2026 08 22;:e4052471

Holdup Multiplex Assay for High-Throughput Measurement of Protein-Ligand Affinity Constants Using a Mass Spectrometry Readout.

Delalande F, Østergaard SR, Gogl G, Cousido-Siah A, McEwen AG, Men Y, Salimova F, Rohrbacher A, Kostmann C, Nominé Y, Vincentelli R, Eberling P, Carapito C, Travé G, Monsellier E

J Am Chem Soc. 2025 03 24;:

The antibacterial properties of branched peptides based on poly(l-arginine): In vitro antibacterial evaluation and molecular dynamic simulations.

Eloïse L, Petit L, Nominé Y, Heurtault B, Ben Hadj Kaddour I, Senger B, Rodon Fores J, Vrana NE, Barbault F, Lavalle P

Eur J Med Chem. 2024 02 10;268:116224

ProFeatMap: a highly customizable tool for 2D feature representation of protein sets.

Bich G, Monsellier E, Travé G, Nominé Y

Bioinform Adv. 2023 03 9;3(1):vbad022

The Cooperative Folding of Annexin A2 Relies on a Transient Non-Native Intermediate.

Hollås H, Ramirez J, Nominé Y, Kostmann C, Toto A, Gianni S, Travé G, Vedeler A

Biophys J. 2022 11 1;:

Quantitative fragmentomics allow affinity mapping of interactomes.

Gogl G, Zambo B, Kostmann C, Cousido-Siah A, Morlet B, Durbesson F, Negroni L, Eberling P, Jané P, Nominé Y, Zeke A, Østergaard S, Monsellier É, Vincentelli R, Travé G

Nat Commun. 2022 09 17;13(1):5472

In vitro characterization of the full-length human dynein-1 cargo adaptor BicD2.

Fagiewicz R, Crucifix C, Klos T, Deville C, Kieffer B, Nominé Y, Busselez J, Rossolillo P, Schmidt H

Structure. 2022 09 14;:

High-Risk Mucosal Human Papillomavirus 16 (HPV16) E6 Protein and Cutaneous HPV5 and HPV8 E6 Proteins Employ Distinct Strategies To Interfere with Interferon Regulatory Factor 3-Mediated Beta Interferon Expression.

Poirson J, Suarez IP, Straub ML, Cousido-Siah A, Peixoto P, Hervouet E, Foster A, Mitschler A, Mukobo N, Chebaro Y, Garcin D, Recberlik S, Gaiddon C, Altschuh D, Nominé Y, Podjarny A, Trave G, Masson M

J Virol. 2022 Apr 27;:e0187521

Small p53 derived peptide suitable for robust nanobodies dimerization.

Dietsch F, Nominé Y, Stoessel A, Kostmann C, Bonhoure A, Chatton B, Donzeau M

J Immunol Methods. 2021 Sep 2;:113144

A Computational Protocol to Analyze PDZ/PBM Affinity Data Obtained by High-Throughput Holdup Assay.

Jané P, Chiron L, Bich G, Travé G, Nominé Y

Methods Mol Biol. 2021 ;2256:61-74

Conformational editing of intrinsically disordered protein by α-methylation.

Bauer V, Schmidtgall B, Gógl G, Dolenc J, Osz J, Nominé Y, Kostmann C, Cousido-Siah A, Mitschler A, Rochel N, Travé G, Kieffer B, Torbeev V

Chem Sci. 2020 Nov 4;12(3):1080-1089

FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

Di Mattia T, Martinet A, Ikhlef S, McEwen AG, Nominé Y, Wendling C, Poussin-Courmontagne P, Voilquin L, Eberling P, Ruffenach F, Cavarelli J, Slee J, Levine TP, Drin G, Tomasetto C, Alpy F

EMBO J. 2020 Oct 30;:e104369

Modular Conjugation of a Potent Anti-HER2 Immunotoxin Using Coassociating Peptides.

Stoessel A, Groysbeck N, Guyot L, Barret L, Nominé Y, Nguekeu-Zebaze L, Bender A, Voilquin L, Lutz T, Pallaoro N, Blocat M, Deville C, Masson M, Zuber G, Chatton B, Donzeau M

Bioconjug. Chem.. 2020 Sep 30;:

Benchtop holdup assay for quantitative affinity-based analysis of sequence determinants of protein-motif interactions.

Bonhoure A, Forster A, Babah KO, Gógl G, Eberling P, Kostmann C, Volkmer R, Mancilla VT, Travé G, Nominé Y

Anal. Biochem.. 2020 May 16;:113772

Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.

Gogl G, Jane P, Caillet-Saguy C, Kostmann C, Bich G, Cousido-Siah A, Nyitray L, Vincentelli R, Wolff N, Nomine Y, Sluchanko NN, Trave G

Structure. 2020 Apr 6;:

Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase.

Jané P, Gógl G, Kostmann C, Bich G, Girault V, Caillet-Saguy C, Eberling P, Vincentelli R, Wolff N, Travé G, Nominé Y

PLoS One. 2020 ;15(12):e0244613

Self-associating peptides for modular bifunctional conjugation of tetramer macromolecules in living cells.

Vigneron M, Dietsch F, Bianchetti L, Dejaegere A, Nominé Y, Cordonnier AM, Zuber G, Chatton B, Donzeau M

Bioconjug. Chem.. 2019 May 15;:

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

Gógl G, Biri-Kovács B, Durbesson F, Jane P, Nomine Y, Kostmann C, Bilics V, Simon M, Reményi A, Vincentelli R, Trave G, Nyitray L

J. Mol. Biol.. 2019 Feb 3;:

High-Quality Data of Protein/Peptide Interaction by Isothermal Titration Calorimetry.

Ramirez J, Nominé Y

Methods Mol. Biol.. 2019 ;1964:99-117

High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay.

Duhoo Y, Girault V, Turchetto J, Ramond L, Durbesson F, Fourquet P, Nominé Y, Cardoso V, Sequeira AF, Brás JLA, Fontes CMGA, Travé G, Wolff N, Vincentelli R

Methods Mol. Biol.. 2019 ;2025:439-476