Dr BARDET Anaïs

Fiche personne

Coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH Cedex

03 88 65 35 25

Territoire

Alsace

Statut

Chercheur

Recherche

Mots clés : Bioinformatique, Génomique, Facteurs de transcription, Méthylation de l'ADN, Apprentissage profond

Projets

Defining the impact of rewiring essential transcription factor binding patterns by single nucleotide polymorphisms and DNA methylation changes in cancer (CancerDependence)

2025 - Porteur du projet : Dr BARDET Anaïs

Identification des facteurs de transcriptions conduisant à une méthylation abberante de l'ADN dans les cellules cancéreuses

2017 - Porteur du projet : Dr BARDET Anaïs

Publications

Range extender mediates long-distance enhancer activity.

Bower G, Hollingsworth EW, Jacinto SH, Alcantara JA, Clock B, Cao K, Liu M, Dziulko A, Alcaina-Caro A, Xu Q, Skowronska-Krawczyk D, Lopez-Rios J, Dickel DE, Bardet AF, Pennacchio LA, Visel A, Kvon EZ

Nature. 2025 07 2;:

MethyLasso: a segmentation approach to analyze DNA methylation patterns and identify differentially methylated regions from whole-genome datasets.

Balaramane D, Spill YG, Weber M, Bardet AF

Nucleic Acids Res. 2024 10 18;:

Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma.

Sundaramoorthy S, Colombo DF, Sanalkumar R, Broye L, Balmas Bourloud K, Boulay G, Cironi L, Stamenkovic I, Renella R, Kuttler F, Turcatti G, Rivera MN, Mühlethaler-Mottet A, Bardet AF, Riggi N

JCI Insight. 2024 07 22;9(14):

Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells.

Al Adhami H, Vallet J, Schaal C, Schumacher P, Bardet AF, Dumas M, Chicher J, Hammann P, Daujat S, Weber M

Nucleic Acids Res. 2023 02 11;:

Pan-cancer predictions of transcription factors mediating aberrant DNA methylation.

Detilleux D, Spill YG, Balaramane D, Weber M, Bardet AF

Epigenetics Chromatin. 2022 Mar 24;15(1):10

A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates.

Al Adhami H, Bardet AF, Dumas M, Cleroux E, Guibert S, Fauque P, Acloque H, Weber M

BMC Biol. 2022 Mar 23;20(1):70

The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency.

Olivieri D, Paramanathan S, Bardet AF, Hess D, Smallwood SA, Elling U, Betschinger J

J Biol Chem. 2021 08;297(2):100947

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Dr BARDET Anaïs

Fiche personne

Coordonnées

Territoire

Statut

Affiliation

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Site web

Recherche

Projets

Defining the impact of rewiring essential transcription factor binding patterns by single nucleotide polymorphisms and DNA methylation changes in cancer (CancerDependence)

Identification des facteurs de transcriptions conduisant à une méthylation abberante de l'ADN dans les cellules cancéreuses

Publications

Range extender mediates long-distance enhancer activity.

MethyLasso: a segmentation approach to analyze DNA methylation patterns and identify differentially methylated regions from whole-genome datasets.

Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma.

Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells.

Pan-cancer predictions of transcription factors mediating aberrant DNA methylation.

A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates.

The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency.

E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.

Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity.

Loss of Apc Rapidly Impairs DNA Methylation Programs and Cell Fate Decisions in Lgr5 Intestinal Stem Cells.

TFmotifView: a webserver for the visualization of transcription factor motifs in genomic regions.

Sensitivity of transcription factors to DNA methylation.

Competition between DNA methylation and transcription factors determines binding of NRF1.

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers.

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