[Erectile function after permanent prostate brachytherapy: A long term prospective study about 157 cases]
Fiche publication
Date publication
avril 2010
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CORMIER Luc, Pr PEIFFERT Didier
Tous les auteurs :
Marcon N, Cormier L, Peiffert D, Mangin P
Lien Pubmed
Résumé
INTRODUCTION: The objective of this study was to determine the impact of the preservation of sexual function in the long-term in patients treated with brachytherapy using a validated self-questionnaire and determine the role of different clinical and therapeutic parameters. MATERIAL AND METHOD: From December 1999 to June 2002, 157 consecutive patients treated by prostate brachytherapy have been selected for the study. A questionnaire of the EORTC "QLQ C30" assorted with the module "PR25" has been submitted before treatment and in the second quarter 2007. Hundred and twenty-eight patients returned their questionnaires (81.5 %). Statistical analysis was made with 64 patients. The median follow-up was 6 years (+/-0.57 year). The settings can interfere with sexual function were assessed: age, prostate volume, co-morbidity, adjuvant hormonal therapy, D 90, V 150 and V 240. Statistical analysis was made by way univariate ANOVA procedure and mode Chi(2) and multivariate (logistic regression), the variable being studied "conservation of sexual activity YES/NO". RESULTS: The conservation rate of sexual function was 64 %. No variable can explain the loss of sexual function is reflected statistically significant (p
Référence
Prog Urol. 2010 Apr;20(4):284-91