Comorbidities alone do not explain the undertreatment of colorectal cancer in older adults: a French population-based study.
Fiche publication
Date publication
avril 2011
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOUVIER Anne-Marie, Dr JOOSTE Valérie, Dr QUIPOURT Valérie, Dr COTTET Vanessa
Tous les auteurs :
Quipourt V, Jooste V, Cottet V, Faivre J, Bouvier AM
Lien Pubmed
Résumé
OBJECTIVES: To investigate the influence of comorbidities on treatment modalities of colorectal cancer according to the age of patients and French recommendations. DESIGN: Population-based study SETTING: French Digestive Cancer Registry, Burgundy. PARTICIPANTS: Two thousand nine hundred twenty-one incident colorectal cancers diagnosed between 2004 and 2007. MEASUREMENTS: The independent influence of comorbidities (recorded according to the Charlson index) on treatment was analyzed using multivariate logistic regressions controlling for age, sex, and their interaction. RESULTS: The association between comorbidities and resection for cure was significant only in patients younger than 75 (P interaction=.008). For Stage III colon cancer, 40.4% of the patients aged 75 and older had adjuvant chemotherapy, versus 90.5% of those younger than 75 (P
Référence
J Am Geriatr Soc. 2011 Apr;59(4):694-8