First estimates of diffuse gastric cancer risks for carriers of germline pathogenic variants.
Fiche publication
Date publication
août 2022
Journal
Journal of medical genetics
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOUVIER Anne-Marie
Tous les auteurs :
Coudert M, Drouet Y, Delhomelle H, Svrcek M, Benusiglio PR, Coulet F, Clark DF, Katona BW, van Hest LP, van der Kolk LE, Cats A, van Dieren JM, Nehoray B, Slavin T, Spier I, Hüneburg R, Lobo S, Oliveira C, Boussemart L, Masson L, Chiesa J, Schwartz M, Buecher B, Golmard L, Bouvier AM, Bonadona V, Stoppa-Lyonnet D, Lasset C, Colas C
Lien Pubmed
Résumé
Pathogenic variants (PV) of are found in families fulfilling criteria for hereditary diffuse gastric cancer (HDGC) but no risk estimates were available until now. The aim of this study is to evaluate diffuse gastric cancer (DGC) risks for carriers of germline PV.
Mots clés
gastroenterology, genetic counseling, genetic predisposition to disease, medical oncology
Référence
J Med Genet. 2022 08 29;: