Mutational analysis of apoptotic genes in familial aggregation of hematological malignancies.
Fiche publication
Date publication
juin 2021
Journal
Bulletin du cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr FAIVRE Laurence
Tous les auteurs :
Hamadou WS, Mani R, Bouali N, Besbes S, Bourdon V, El Abed R, Ben Youssef Y, Mari V, Gesta P, Dreyfus H, Bonadona V, Dugast C, Zattara H, Faivre L, Noguchi T, Khélif A, Sobol H, Soua Z
Lien Pubmed
Résumé
Apoptosis deregulation have been associated to tumorigenesis process and was highlighted as a prominent hallmark of cancer. Several mutations have been reported in several forms of Blood cancer. However, it has never been investigated in familial aggregations of hematological malignancies.
Mots clés
CASP10, CASP8, FAS, FASLG, Familial hematological malignancies, Hémopathies malignes familiales, PRF1
Référence
Bull Cancer. 2021 Jun 14;: