Lactobacillus stress protein GroEL prevents colonic inflammation.
Fiche publication
Date publication
mars 2021
Journal
Journal of gastroenterology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GARRIDO Carmen, Dr HERMETET François, Pr ORTEGA DEBALLON Pablo, Pr LIRUSSI Frédéric, Dr DEMIDOV Oleg, Pr CHLUBA Johanna
Tous les auteurs :
Dias AMM, Douhard R, Hermetet F, Regimbeau M, Lopez TE, Gonzalez D, Masson S, Marcion G, Chaumonnot K, Uyanik B, Causse SZ, Rieu A, Hadi T, Basset C, Chluba J, Grober J, Guzzo J, Neiers F, Ortega-Deballon P, Demidov ON, Lirussi F, Garrido C
Lien Pubmed
Résumé
We previously showed that supernatants of Lactobacillus biofilms induced an anti-inflammatory response by affecting the secretion of macrophage-derived cytokines, which was abrogated upon immunodepletion of the stress protein GroEL.
Mots clés
Colonic inflammation, GroEL, IBD (inflammatory bowel disease), Macrophages, Probiotics
Référence
J Gastroenterol. 2021 Mar 29;: