MTHFR 677C → T genotype modulates the effect of a 5-year supplementation with B-vitamins on homocysteine concentration: The SU.FOL.OM3 randomized controlled trial.
Fiche publication
Date publication
janvier 2018
Journal
PloS one
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GUEANT Jean-Louis
Tous les auteurs :
Fezeu LK, Ducros V, Guéant JL, Guilland JC, Andreeva VA, Hercberg S, Galan P
Lien Pubmed
Résumé
To study how MTHFR 677C→T genotype modulates the effect of supplementation with B-vitamins on total homocysteine (tHcy) and B-vitamin concentrations.
Mots clés
Cardiovascular Diseases, drug therapy, Dietary Supplements, Double-Blind Method, Female, Genotype, Homocysteine, blood, Humans, Male, Methylenetetrahydrofolate Reductase (NADPH2), genetics, Middle Aged, Polymorphism, Genetic, Vitamin B Complex, administration & dosage
Référence
PLoS ONE. 2018 ;13(5):e0193352