Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102.
Fiche publication
Date publication
avril 2007
Journal
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BEDENNE Laurent, Pr BINQUET Christine, Pr BOUCHE Olivier, Pr CONROY Thierry
Tous les auteurs :
Bedenne L, Michel P, Bouché O, Milan C, Mariette C, Conroy T, Pezet D, Roullet B, Seitz JF, Herr JP, Paillot B, Arveux P, Bonnetain F, Binquet C
Lien Pubmed
Résumé
Uncontrolled studies suggest that chemoradiation has similar efficacy as surgery for esophageal cancer. Therefore, a randomized trial was carried out to compare, in responders only, chemoradiation alone with chemoradiation followed by surgery in patients with locally advanced tumors.
Mots clés
Aged, Antineoplastic Combined Chemotherapy Protocols, adverse effects, Carcinoma, Squamous Cell, mortality, Combined Modality Therapy, Esophageal Neoplasms, mortality, Female, Humans, Length of Stay, Male, Middle Aged, Positron-Emission Tomography, Quality of Life, Radiotherapy, adverse effects, Radiotherapy Dosage
Référence
J. Clin. Oncol.. 2007 Apr;25(10):1160-8