Incidence and patterns of recurrence after resection for cure of colonic cancer in a well defined population.

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Date publication

septembre 2006

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BOUVIER Anne-Marie, Dr DANCOURT Vincent, Pr LEPAGE Côme


Tous les auteurs :
Manfredi S, Bouvier AM, Lepage C, Hatem C, Dancourt V, Faivre J

Résumé

BACKGROUND: The aim of this study was to determine the incidence and patterns of failure following potentially curative surgery of colonic cancer. METHODS: Data were obtained from the cancer registry of the Cote-d'Or (France). Data on 2657 patients who had resection for cure of colonic cancer between 1976 and 2000 were analysed. Local and distant failure rates were calculated using the actuarial method and multivariable analysis was performed using a Cox model. RESULTS: The 5-year cumulative rate was 12.8 percent for local recurrence and 25.6 percent for distant metastases. Five-year cumulative local recurrence rates were 4.9 percent for stage I, 11.0 percent for stage II and 23.5 percent for stage III tumours (P

Référence

Br J Surg. 2006 Sep;93(9):1115-22.