Management and prognosis of pancreatic cancer over a 30-year period.
Fiche publication
Date publication
juillet 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOUVIER Anne-Marie, Dr JOOSTE Valérie, Dr JOUVE Jean-Louis, Pr LEPAGE Côme
Tous les auteurs :
David M, Lepage C, Jouve JL, Jooste V, Chauvenet M, Faivre J, Bouvier AM
Lien Pubmed
Résumé
BACKGROUND: The aim of this study was to report on changes in the diagnostic assessment, patterns of care and survival over time for pancreatic cancers.METHODS: A total of 2986 cases of pancreatic cancer from the Digestive Cancer Registry of Burgundy (France) over a 30-year period (1976-2005) were considered. Non-conditional logistic regressions were carried out to identify the factors associated with resection for cure and with the use of chemotherapy. A multivariate relative survival analysis was carried out.RESULTS: Diagnostic procedures have changed. Ultrasonography and computed tomography progressively have become the major diagnostic procedures. There was a slight improvement in stage: the proportion of stage I-II was 2.8% in the 1976-1980 period and 8.8% in the 2001-2005 period (P
Référence
Br J Cancer. 2009 Jul 21;101(2):215-8