EN DE

Dr DUMOND Hélène

Fiche personne

coordonnées

CRAN
Bd des Aiguillettes
BP 70239
54506 VANDOEUVRE-LES-NANCY Cedex

03 72 74 61 15

helene.dumond@univ-lorraine.fr

Territoire

Lorraine

Statut

Enseignant-Chercheur

affiliation

Université de Lorraine (UL)

Centre de Recherche en Automatique de Nancy (CRAN) - UMR 7039 (CRAN)

équipes/plateformes

Equipe UMR 7039 - Equipe "Biologie, Signaux et Systèmes en Cancérologie et Neurosciences (BioSIS)"

Projets

Impact anti-tumoral de l’expression et de la fonctionnalité du récepteur membranaire des œstrogènes GPER sur les glioblastomes

2022 - Porteur du projet : Dr DUMOND Hélène

Mécanismes d'action des œstrogènes et progestatifs dans la progression des gliomes de bas grade (Pro-Glio)

2020 - Porteur du projet : Dr RECH Fabien - Partenaires : Dr DUBOIS-POT-SCHNEIDER Hélène, Dr DUMOND Hélène, Dr PINEL Sophie, Pr TAILLANDIER Luc, Pr GAUCHOTTE Guillaume

Etude prospective de validation d'ERα36, nouveau marqueur moléculaire pronostique de progression tumorale dans les cancers du sein

2015 - Porteur du projet : Dr DUMOND Hélène

Characterization of ER-alpha-36 natural and synthetic ligands for the modulation of hormone-sensitive tumor initiation and progression

2013 - Porteur du projet : Dr DUMOND Hélène

Publications

Estrogen signaling in healthy and tumor brain.

Hirtz A, Rech F, Dubois-Pot-Schneider H, Dumond H

Steroids. 2023 08 3;:109285

Molecular Characterization of the Dual Effect of the GPER Agonist G-1 in Glioblastoma.

Hirtz A, Bailly Y, Rech F, Pierson J, Dumond H, Dubois-Pot-Schneider H

Int J Mol Sci. 2022 11 18;23(22):

Identification of Gender- and Subtype-Specific Gene Expression Associated with Patient Survival in Low-Grade and Anaplastic Glioma in Connection with Steroid Signaling.

Hirtz A, Lebourdais N, Thomassin M, Rech F, Dumond H, Dubois-Pot-Schneider H

Cancers (Basel). 2022 08 25;14(17):

GPER Agonist G-1 Disrupts Tubulin Dynamics and Potentiates Temozolomide to Impair Glioblastoma Cell Proliferation.

Hirtz A, Lebourdais N, Rech F, Bailly Y, Vaginay A, Smaïl-Tabbone M, Dubois-Pot-Schneider H, Dumond H

Cells. 2021 12 7;10(12):

Astrocytoma: A Hormone-Sensitive Tumor?

Hirtz A, Rech F, Dubois-Pot-Schneider H, Dumond H

Int J Mol Sci. 2020 Nov 30;21(23):

A statistical methodology to select covariates in high-dimensional data under dependence. Application to the classification of genetic profiles in oncology.

Bastien B, Boukhobza T, Dumond H, Gégout-Petit A, Muller-Gueudin A, Thiébaut C

J Appl Stat. 2020 10 27;49(3):764-781

The Role of ERα36 in Development and Tumor Malignancy.

Thiebaut C, Konan HP, Guerquin MJ, Chesnel A, Livera G, Le Romancer M, Dumond H

Int J Mol Sci. 2020 Jun 9;21(11):

Dual Epigenetic Regulation of ERα36 Expression in Breast Cancer Cells.

Thiebaut C, Chesnel A, Merlin JL, Chesnel M, Leroux A, Harlé A, Dumond H

Int J Mol Sci. 2019 May 29;20(11):

Low-Dose Alkylphenol Exposure Promotes Mammary Epithelium Alterations and Transgenerational Developmental Defects, But Does Not Enhance Tumorigenic Behavior of Breast Cancer Cells.

Chamard-Jovenin C, Thiebaut C, Chesnel A, Bresso E, Morel C, Smail-Tabbone M, Devignes MD, Boukhobza T, Dumond H

Front Endocrinol (Lausanne). 2017 ;8:272

Mammary epithelial cell phenotype disruption in vitro and in vivo through ERalpha36 overexpression.

Thiebaut C, Chamard-Jovenin C, Chesnel A, Morel C, Djermoune EH, Boukhobza T, Dumond H

PLoS ONE. 2017 ;12(3):e0173931

From ERalpha66 to ERalpha36: a generic method for validating a prognosis marker of breast tumor progression.

Chamard-Jovenin C, Jung AC, Chesnel A, Abecassis J, Flament S, Ledrappier S, Macabre C, Boukhobza T, Dumond H

BMC Syst Biol. 2015 Jun 17;9(1):28

Mullerian inhibiting substance in the caudate amphibian Pleurodeles waltl.

Al-Asaad I, Chardard D, di Clemente N, Picard JY, Dumond H, Chesnel A, Flament S

Endocrinology. 2013 Oct;154(10):3931-6

An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism.

Ajj H, Chesnel A, Pinel S, Plenat F, Flament S, Dumond H

PLoS One. 2013 Apr 23;8(4):e61758

Busulfan-mediated germ cell depletion does not alter gonad differentiation in the urodele amphibian Pleurodeles waltl.

Al-Asaad I, Dumond H, Chardard D, Chesnel A, Flament S

Sex Dev. 2012;6(4):188-200

Temporal and spatial SOX9 expression patterns in the course of gonad development of the caudate amphibian Pleurodeles waltl.

Dumond H, Al-Asaad I, Chesnel A, Chardard D, Boizet-Bonhoure B, Flament S, Kuntz S

J Exp Zool B Mol Dev Evol. 2011 May 15;316B(3):199-211

[Is leptin the missing link between osteoarthritis and obesity?].

Terlain B, Dumond H, Presle N, Mainard D, Bianchi A, Loeuille D, Netter P, Pottie P

Ann Pharm Fr. 2005 Jun;63(3):186-93.