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Multiomics of three hematological malignancies in a patient reveal their origin from clonal hematopoietic stem cells.

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Blood Cancer J. 2023 08 9;13(1):118

Effect of an intraoperative periradicular application of platelet-rich fibrin (PRF) on residual post-surgical neuropathic pain after disc herniation surgery: study protocol for NeuroPRF, a randomized controlled trial.

Todeschi J, Dannhoff G, Coca AH, Timbolschi DI, Proust F, Lefebvre F, Lelievre V, Poisbeau P, Vallat L, Salvat E, Bohren Y

Trials. 2023 06 19;24(1):418

Bruton's tyrosine kinase (BTK) gene overexpression is associated with risk of lymphoma in primary Sjögren's syndrome.

Duret PM, Schleiss C, Kawka L, Meyer N, Ye T, Saraux A, Devauchelle-Pensec V, Seror R, Larroche C, Perdriger A, Sibilia J, Vallat L, Fornecker LM, Nocturne G, Mariette X, Gottenberg JE

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Molecular heterogeneity and measurable residual disease of rare NPM1 mutations in acute myeloid leukemia: a nationwide experience from the GBMHM study group.

Fournier E, Heiblig M, Lespinasse C, Flandrin-Gresta P, Geay A, Miguet L, Fenwarth L, Vallat L, Soubeyrand B, Marceau-Renaut A, Plesa A, Preudhomme C, Sujobert P, Hayette S, Duployez N, Huet S

Leukemia. 2022 Mar 7;:

Direct Targeting Mutation in Non-Small Cell Lung Cancer: Focus on Resistance.

Reita D, Pabst L, Pencreach E, Guérin E, Dano L, Rimelen V, Voegeli AC, Vallat L, Mascaux C, Beau-Faller M

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Molecular Mechanism of EGFR-TKI Resistance in -Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring.

Reita D, Pabst L, Pencreach E, Guérin E, Dano L, Rimelen V, Voegeli AC, Vallat L, Mascaux C, Beau-Faller M

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CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition.

Galland A, Gourain V, Habbas K, Güler Y, Martin E, Ebel C, Tavian M, Vallat L, Chenard MP, Mauvieux L, Freund JN, Duluc I, Domon-Dell C

Mol Oncol. 2021 May 6;:

CDX2 regulates ACE expression in blood development and leukemia cells.

El Omar R, Julien E, Biasch K, Guffroy B, Lioure B, Vallat L, Gross I, Domon-Dell C, Lanza F, Gachet C, Negroni M, Freund JN, Tavian M

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Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia.

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Leukemia. 2021 Apr 8;:

SelectBoost: a general algorithm to enhance the performance of variable selection methods.

Bertrand F, Aouadi I, Jung N, Carapito R, Vallat L, Bahram S, Maumy-Bertrand M

Bioinformatics. 2020 Oct 5;:

Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma.

Fornecker LM, Muller L, Bertrand F, Paul N, Pichot A, Herbrecht R, Chenard MP, Mauvieux L, Vallat L, Bahram S, Cianférani S, Carapito R, Carapito C

Sci Rep. 2019 Jan 29;9(1):895

BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo.

Schleiss C, Ilias W, Tahar O, Güler Y, Miguet L, Mayeur-Rousse C, Mauvieux L, Fornecker LM, Toussaint E, Herbrecht R, Bertrand F, Maumy-Bertrand M, Martin T, Fournel S, Georgel P, Bahram S, Vallat L

Sci Rep. 2019 Jan 24;9(1):701

Reduced DICER1 Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli.

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Clinical laboratory medicine: continuous amelioration with a book of objectives and satisfaction survey.

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Cascade: a R package to study, predict and simulate the diffusion of a signal through a temporal gene network.

Jung N, Bertrand F, Bahram S, Vallat L, Maumy-Bertrand M

Bioinformatics. 2014 Feb 15;30(4):571-3

Reverse-engineering the genetic circuitry of a cancer cell with predicted intervention in chronic lymphocytic leukemia.

Vallat L, Kemper CA, Jung N, Maumy-Bertrand M, Bertrand F, Meyer N, Pocheville A, Fisher JW 3rd, Gribben JG, Bahram S

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):459-64

Waldenstrom's macroglobulinemia harbors a unique proteome where Ku70 is severely underexpressed as compared with other B-lymphoproliferative disorders.

Perrot A, Pionneau C, Azar N, Baillou C, Lemoine FM, Leblond V, Merle-Beral H, Bene MC, Herbrecht R, Bahram S, Vallat L

Blood Cancer J. 2012 Sep 7;2:e88

A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia.

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