Zouiouich M, Di Mattia T, Martinet A, Eichler J, Wendling C, Tomishige N, Grandgirard E, Fuggetta N, Fromental-Ramain C, Mizzon G, Dumesnil C, Carpentier M, Reina-San-Martin B, Mathelin C, Schwab Y, Thiam AR, Kobayashi T, Drin G, Tomasetto C, Alpy F

J Cell Biol. 2022 Jun 6;221(6):

Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations.

Mitrentsi I, Lou J, Kerjouan A, Verigos J, Reina-San-Martin B, Hinde E, Soutoglou E

Mol Cell. 2022 Apr 13;:

Evolutionary conservation of centriole rotational asymmetry in the human centrosome.

Gaudin N, Martin Gil P, Boumendjel M, Ershov D, Pioche-Durieu C, Bouix M, Delobelle Q, Maniscalco L, Phan TBN, Heyer V, Reina-San-Martin B, Azimzadeh J

Elife. 2022 Mar 23;11:

Activation of homologous recombination in G1 preserves centromeric integrity.

Yilmaz D, Furst A, Meaburn K, Lezaja A, Wen Y, Altmeyer M, Reina-San-Martin B, Soutoglou E

Nature. 2021 Dec 1;:

Fam72a enforces error-prone DNA repair during antibody diversification.

Rogier M, Moritz J, Robert I, Lescale C, Heyer V, Abello A, Martin O, Capitani K, Thomas M, Thomas-Claudepierre AS, Laffleur B, Jouan F, Pinaud E, Tarte K, Cogné M, Conticello SG, Soutoglou E, Deriano L, Reina-San-Martin B

Nature. 2021 Nov 24;:

The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms.

Fischer V, Plassard D, Ye T, Reina-San-Martin B, Stierle M, Tora L, Devys D

Cell Rep. 2021 Aug 24;36(8):109598

Integrity of the short arm of the nuclear pore Y-complex is required for mouse embryonic stem cell growth and differentiation.

Gonzalez-Estevez A, Verrico A, Orniacki C, Reina-San-Martin B, Doye V

J Cell Sci. 2021 May 15;134(10):

AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation.

Ghodke I, Remisova M, Furst A, Kilic S, Reina-San-Martin B, Poetsch AR, Altmeyer M, Soutoglou E

Mol Cell. 2021 Apr 29;:

Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome.

Helfricht A, Thijssen PE, Rother MB, Shah RG, Du L, Takada S, Rogier M, Moritz J, IJspeert H, Stoepker C, van Ostaijen-Ten Dam MM, Heyer V, Luijsterburg MS, de Groot A, Jak R, Grootaers G, Wang J, Rao P, Vertegaal ACO, van Tol MJD, Pan-Hammarström Q, Reina-San-Martin B, Shah GM, van der Burg M, van der Maarel SM, van Attikum H

J. Exp. Med.. 2020 Nov 2;217(11):

A novel regulatory region controls IgH locus transcription and switch recombination to a subset of isotypes.

Amoretti-Villa R, Rogier M, Robert I, Heyer V, Reina-San-Martin B

Cell. Mol. Immunol.. 2019 Aug 5;:

Allele-Specific CRISPR/Cas9 Correction of a Heterozygous DNM2 Mutation Rescues Centronuclear Myopathy Cell Phenotypes.

Rabai A, Reisser L, Reina-San-Martin B, Mamchaoui K, Cowling BS, Nicot AS, Laporte J

Mol Ther Nucleic Acids. 2019 Feb 27;16:246-256

COSPLAY: An expandable toolbox for combinatorial and swift generation of expression plasmids in yeast.

Goulev Y, Matifas A, Heyer V, Reina-San-Martin B, Charvin G

PLoS ONE. 2019 ;14(8):e0220694

PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers.

Beck C, Rodriguez-Vargas JM, Boehler C, Robert I, Heyer V, Hanini N, Gauthier LR, Tissier A, Schreiber V, Elofsson M, Reina San Martin B, Dantzer F

Cell Death Differ.. 2018 Nov 15;:

Mediator contributes to IgH locus VDJ rearrangements by promoting usage of most distal V segments.

Dalloul I, Dalloul Z, Le Noir S, Boyer F, Reina-San-Martin B, Cook-Moreau J, Cogné M

Cell. Mol. Immunol.. 2018 Nov 7;:

Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.

Souquet B, Freed E, Berto A, Andric V, Audugé N, Reina-San-Martin B, Lacy E, Doye V

Cell Rep. 2018 May 22;23(8):2443-2454

Imaging of native transcription factors and histone phosphorylation at high resolution in live cells.

Conic S, Desplancq D, Ferrand A, Fischer V, Heyer V, Reina San Martin B, Pontabry J, Oulad-Abdelghani M, Babu N K, Wright GD, Molina N, Weiss E, Tora L

J. Cell Biol.. 2018 Apr 2;217(4):1537-1552

Med1 deficiency alters the somatic hypermutation spectrum in murine B cells.

Gaudot L, Thomas-Claudepierre AS, Robert I, Schiavo E, Heyer V, Reina-San-Martin B

Eur. J. Immunol.. 2018 Apr;48(4):720-723

Trib1 Is Overexpressed in Systemic Lupus Erythematosus, While It Regulates Immunoglobulin Production in Murine B Cells.

Simoni L, Delgado V, Ruer-Laventie J, Bouis D, Soley A, Heyer V, Robert I, Gies V, Martin T, Korganow AS, San Martin BR, Soulas-Sprauel P

Front Immunol. 2018 ;9:373

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

Tacconi EM, Lai X, Folio C, Porru M, Zonderland G, Badie S, Michl J, Sechi I, Rogier M, Matía García V, Batra AS, Rueda OM, Bouwman P, Jonkers J, Ryan A, Reina-San-Martin B, Hui J, Tang N, Bruna A, Biroccio A, Tarsounas M

EMBO Mol Med. 2017 Jul;:

DNA end resection requires constitutive sumoylation of CtIP by CBX4.

Soria-Bretones I, Cepeda-García C, Checa-Rodriguez C, Heyer V, Reina-San-Martin B, Soutoglou E, Huertas P

Nat Commun. 2017 Jul;8(1):113

Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice.

Robert I, Gaudot L, Yélamos J, Noll A, Wong HK, Dantzer F, Schreiber V, Reina-San-Martin B

Eur. J. Immunol.. 2017 Jan;:

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.

Lescale C, Lenden Hasse H, Blackford AN, Balmus G, Bianchi JJ, Yu W, Bacoccina L, Jarade A, Clouin C, Sivapalan R, Reina-San-Martin B, Jackson SP, Deriano L

Cell Rep. 2016 Sep;16(11):2967-79

Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways within Mammalian Heterochromatin.

Tsouroula K, Furst A, Rogier M, Heyer V, Maglott-Roth A, Ferrand A, Reina-San-Martin B, Soutoglou E

Mol. Cell. 2016 Jul;63(2):293-305

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.

Thomas-Claudepierre AS, Robert I, Rocha PP, Raviram R, Schiavo E, Heyer V, Bonneau R, Luo VM, Reddy JK, Borggrefe T, Skok JA, Reina-San-Martin B

J. Exp. Med.. 2016 Mar;213(3):303-12

Parp3 negatively regulates immunoglobulin class switch recombination.

Robert I, Gaudot L, Rogier M, Heyer V, Noll A, Dantzer F, Reina-San-Martin B

PLoS Genet.. 2015 May;11(5):e1005240

Nuclear position dictates DNA repair pathway choice.

Lemaitre C, Grabarz A, Tsouroula K, Andronov L, Furst A, Pankotai T, Heyer V, Rogier M, Attwood KM, Kessler P, Dellaire G, Klaholz B, Reina-San-Martin B, Soutoglou E

Genes Dev. 2014 Nov 15;28(22):2450-63

Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3.

Beck C, Robert I, Reina-San-Martin B, Schreiber V, Dantzer F

Exp Cell Res. 2014 Nov 15;329(1):18-25

The cohesin complex regulates immunoglobulin class switch recombination.

Thomas-Claudepierre AS, Schiavo E, Heyer V, Fournier M, Page A, Robert I, Reina-San-Martin B

J Exp Med. 2013 Nov 18;210(12):2495-502

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.

Rouaud P, Vincent-Fabert C, Saintamand A, Fiancette R, Marquet M, Robert I, Reina-San-Martin B, Pinaud E, Cogne M, Denizot Y

J Exp Med. 2013 Jul 29;210(8):1501-7

A role for the RNA pol II-associated PAF complex in AID-induced immune diversification.

Willmann KL, Milosevic S, Pauklin S, Schmitz KM, Rangam G, Simon MT, Maslen S, Skehel M, Robert I, Heyer V, Schiavo E, Reina-San-Martin B, Petersen-Mahrt SK

J Exp Med. 2012 Oct 22;209(11):2099-111

DNA in 3R: Repair, Replication, and Recombination.

Coin F, Reina-San-Martin B, Giglia-Mari G, Berneburg M

Mol Biol Int. 2012;2012:658579

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.

Jeevan-Raj BP, Robert I, Heyer V, Page A, Wang JH, Cammas F, Alt FW, Losson R, Reina-San-Martin B

J Exp Med. 2011 Aug 1;208(8):1649-60

Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.

Buache E, Etique N, Alpy F, Stoll I, Muckensturm M, Reina-San-Martin B, Chenard MP, Tomasetto C, Rio MC

Oncogene. 2011 Jul 21;30(29):3261-73

PARP-3 and APLF function together to accelerate nonhomologous end-joining.

Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW

Mol Cell. 2011 Jan 7;41(1):33-45.

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.

Pavri R, Gazumyan A, Jankovic M, Di Virgilio M, Klein I, Ansarah-Sobrinho C, Resch W, Yamane A, San-Martin BR, Barreto V, Nieland TJ, Root DE, Casellas R, Nussenzweig MC

Cell. 2010 Oct 1;143(1):122-33.

Ikaros controls isotype selection during immunoglobulin class switch recombination.

Sellars M, Reina-San-Martin B, Kastner P, Chan S

J Exp Med. 2009 May 11;206(5):1073-87

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination.

Robert I, Dantzer F, Reina-San-Martin B

J Exp Med. 2009 May 11;206(5):1047-56

Dr REINA-SAN-MARTIN Bernardo

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