Li Y, Tan Z, Zhang Y, Zhang Z, Hu Q, Liang K, Jun Y, Ye Y, Li YC, Li C, Liao L, Xu J, Xing Z, Pan Y, Chatterjee SS, Nguyen TK, Hsiao H, Egranov SD, Putluri N, Coarfa C, Hawke DH, Gunaratne PH, Tsai KL, Han L, Hung MC, Calin GA, Namour F, Guéant JL, Muntau AC, Blau N, Sutton VR, Schiff M, Feillet F, Zhang S, Lin C, Yang L

Science. 2021 Aug 6;373(6555):662-673

The spectrum of biochemical alterations associated with organ dysfunction and inflammatory status and their association with disease outcomes in severe COVID-19: A longitudinal cohort and time-series design study.

Oussalah A, Gleye S, Urmes IC, Laugel E, Barbé F, Orlowski S, Malaplate C, Aimone-Gastin I, Caillierez BM, Merten M, Jeannesson E, Kormann R, Olivier JL, Rodriguez-Guéant RM, Namour F, Bevilacqua S, Thilly N, Losser MR, Kimmoun A, Frimat L, Levy B, Gibot S, Schvoerer E, Guéant JL

. 2020 Sep 20;:100554

Long-Term ACE Inhibitor/ARB Use Is Associated with Severe Renal Dysfunction and Acute Kidney Injury in Patients with severe COVID-19: Results from a Referral Center Cohort in the North East of France.

Oussalah A, Gleye S, Clerc Urmes I, Laugel E, Callet J, Barbé F, Orlowski S, Malaplate C, Aimone-Gastin I, Caillierez BM, Merten M, Jeannesson E, Kormann R, Olivier JL, Rodriguez-Guéant RM, Namour F, Bevilacqua S, Losser MR, Levy B, Kimmoun A, Gibot S, Thilly N, Frimat L, Schvoerer E, Guéant JL

Clin. Infect. Dis.. 2020 Jul 5;:

The Genetic Landscape and Epidemiology of Phenylketonuria.

Hillert A, Anikster Y, Belanger-Quintana A, Burlina A, Burton BK, Carducci C, Chiesa AE, Christodoulou J, Đorđević M, Desviat LR, Eliyahu A, Evers RAF, Fajkusova L, Feillet F, Bonfim-Freitas PE, Giżewska M, Gundorova P, Karall D, Kneller K, Kutsev SI, Leuzzi V, Levy HL, Lichter-Konecki U, Muntau AC, Namour F, Oltarzewski M, Paras A, Perez B, Polak E, Polyakov AV, Porta F, Rohrbach M, Scholl-Bürgi S, Spécola N, Stojiljković M, Shen N, Santana-da Silva LC, Skouma A, van Spronsen F, Stoppioni V, Thöny B, Trefz FK, Vockley J, Yu Y, Zschocke J, Hoffmann GF, Garbade SF, Blau N

Am. J. Hum. Genet.. 2020 Jul 1;:

Coronavirus disease 2019: acute Fanconi syndrome precedes acute kidney injury.

Kormann R, Jacquot A, Alla A, Corbel A, Koszutski M, Voirin P, Garcia Parrilla M, Bevilacqua S, Schvoerer E, Gueant JL, Namour F, Levy B, Frimat L, Oussalah A

Clin Kidney J. 2020 Jun;13(3):362-370

Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles.

Guéant JL, Oussalah A, Zgheib R, Siblini Y, Hsu SB, Namour B

Biochimie. 2020 Apr 11;:

Population and evolutionary genetics of the PAH locus to uncover overdominance and adaptive mechanisms in phenylketonuria: Results from a multiethnic study.

Oussalah A, Jeannesson-Thivisol E, Chéry C, Perrin P, Rouyer P, Josse T, Cano A, Barth M, Fouilhoux A, Mention K, Labarthe F, Arnoux JB, Maillot F, Lenaerts C, Dumesnil C, Wagner K, Terral D, Broué P, De Parscau L, Gay C, Kuster A, Bédu A, Besson G, Lamireau D, Odent S, Masurel A, Rodriguez-Guéant RM, Feillet F, Guéant JL, Namour F

EBioMedicine. 2020 Jan 7;51:102623

Folate can promote the methionine-dependent reprogramming of glioblastoma cells towards pluripotency.

Zgheib R, Battaglia-Hsu SF, Hergalant S, Quéré M, Alberto JM, Chéry C, Rouyer P, Gauchotte G, Guéant JL, Namour F

Cell Death Dis. 2019 Aug 8;10(8):596

Plasma mSEPT9: A Novel Circulating Cell-free DNA-Based Epigenetic Biomarker to Diagnose Hepatocellular Carcinoma.

Oussalah A, Rischer S, Bensenane M, Conroy G, Filhine-Tresarrieu P, Debard R, Forest-Tramoy D, Josse T, Reinicke D, Garcia M, Luc A, Baumann C, Ayav A, Laurent V, Hollenbach M, Ripoll C, Guéant-Rodriguez RM, Namour F, Zipprich A, Fleischhacker M, Bronowicki JP, Guéant JL

EBioMedicine. 2018 Apr;30:138-147

Association of TCN2 rs1801198 c.776G>C polymorphism with markers of one-carbon metabolism and related diseases: a systematic review and meta-analysis of genetic association studies.

Oussalah A, Levy J, Filhine-Trésarrieu P, Namour F, Guéant JL

Am. J. Clin. Nutr.. 2017 Aug;:

Genotype-phenotype associations in French patients with phenylketonuria and importance of genotype for full assessment of tetrahydrobiopterin responsiveness.

Jeannesson-Thivisol E, Feillet F, Chéry C, Perrin P, Battaglia-Hsu SF, Herbeth B, Cano A, Barth M, Fouilhoux A, Mention K, Labarthe F, Arnoux JB, Maillot F, Lenaerts C, Dumesnil C, Wagner K, Terral D, Broué P, de Parscau L, Gay C, Kuster A, Bédu A, Besson G, Lamireau D, Odent S, Masurel A, Guéant JL, Namour F

Orphanet J Rare Dis. 2015 Dec;10:158

Diagnostic Accuracy of Procalcitonin for Predicting Blood Culture Results in Patients With Suspected Bloodstream Infection: An Observational Study of 35,343 Consecutive Patients (A STROBE-Compliant Article).

Oussalah A, Ferrand J, Filhine-Tresarrieu P, Aissa N, Aimone-Gastin I, Namour F, Garcia M, Lozniewski A, Gueant JL

Medicine (Baltimore). 2015 Nov;94(44):e1774

Comparison of cytokine gene polymorphism in drug-induced maculopapular eruption, urticaria and drug reaction with eosinophilia and systemic symptoms (DRESS).

Barbaud A, Waton J, Herbeth B, Bursztejn AC, Bollaert M, Schmutz JL, Gueant-Rodriguez RM, Namour F, Gueant JL, Aimone-Gastin I

J Eur Acad Dermatol Venereol. 2014 Apr;28(4):491-9

CARM1 and PRMT1 are dysregulated in lung cancer without hierarchical features.

Elakoum R, Gauchotte G, Oussalah A, Wissler MP, Clement-Duchene C, Vignaud JM, Gueant JL, Namour F

Biochimie. 2014 Feb;97:210-8

Folate and fetal programming: a play in epigenomics?

Gueant JL, Namour F, Gueant-Rodriguez RM, Daval JL

Trends Endocrinol Metab. 2013 Jun;24(6):279-89

Molecular and cellular effects of vitamin B12 in brain, myocardium and liver through its role as co-factor of methionine synthase.

Gueant JL, Caillerez-Fofou M, Battaglia-Hsu S, Alberto JM, Freund JN, Dulluc I, Adjalla C, Maury F, Merle C, Nicolas JP, Namour F, Daval JL

Biochimie. 2013 May;95(5):1033-40

Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses.

Pellanda H, Forges T, Bressenot A, Chango A, Bronowicki JP, Gueant JL, Namour F

Mol Nutr Food Res. 2012 Jun;56(6):976-85

A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.

Pellanda H, Namour F, Fofou-Caillierez M, Bressenot A, Alberto JM, Chery C, Ayav A, Bronowicki JP, Gueant JL, Forges T

Int J Biochem Cell Biol. 2012 Feb;44(2):385-92

Luminal expression of cubilin is impaired in Imerslund-Grasbeck syndrome with compound AMN mutations in intron 3 and exon 7.

Namour F, Dobrovoljski G, Chery C, Audonnet S, Feillet F, Sperl W, Gueant JL

Haematologica. 2011 Nov;96(11):1715-9

Methyl deficient diet aggravates experimental colitis in rats.

Chen M, Peyrin-Biroulet L, George A, Coste F, Bressenot A, Bossenmeyer-Pourie C, Alberto JM, Xia B, Namour B, Gueant JL

J Cell Mol Med. 2011 Nov;15(11):2486-97

Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors.

Lu X, Freund JN, Muller M, Ravey J, Nicolas JP, Gueant JL, Namour F

Biochimie. 2008 May;90(5):697-704

Lack of association between microsatellite instability and benign adrenal tumors.

Namour F, Ayav A, Lu X, Klein M, Muresan M, Bresler L, Tramoy D, Gueant JL, Brunaud L

World J Surg. 2006 Jul;30(7):1240-6.

Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations.

Gueant-Rodriguez RM, Gueant JL, Debard R, Thirion S, Hong LX, Bronowicki JP, Namour F, Chabi NW, Sanni A, Anello G, Bosco P, Romano C, Amouzou E, Arrieta HR, Sanchez BE, Romano A, Herbeth B, Guilland JC, Mutchinick OM

Am J Clin Nutr. 2006 Mar;83(3):701-7.

The association between plasma homocysteine and holo-transcobalamin and the transcobalamin 776C-->G polymorphism is influenced by folate in the absence of supplementation and fortified diet.

Gueant JL, Xiaohong L, Ortiou S, Gerard P, Shue S, Namour F

Am J Clin Nutr. 2006 Jan;83(1):171-2.