Sencio V, Barthelemy A, Tavares LP, Machado MG, Soulard D, Cuinat C, Queiroz-Junior CM, Noordine ML, Salomé-Desnoulez S, Deryuter L, Foligné B, Wahl C, Frisch B, Vieira AT, Paget C, Milligan G, Ulven T, Wolowczuk I, Faveeuw C, Le Goffic R, Thomas M, Ferreira S, Teixeira MM, Trottein F

Cell Rep. 2020 Mar 3;30(9):2934-2947.e6

A mouse model of MSU-induced acute inflammation suggests imiquimod-dependent targeting of as relevant therapy for gout patients.

Mariotte A, De Cauwer A, Po C, Abou-Faycal C, Pichot A, Paul N, Aouadi I, Carapito R, Frisch B, Macquin C, Chatelus E, Sibilia J, Armspach JP, Bahram S, Georgel P

Theranostics. 2020 ;10(5):2158-2171

Optimization of peptide-based cancer vaccine compositions, by sequential screening, using versatile liposomal platform.

Jacoberger-Foissac C, Saliba H, Seguin C, Brion A, Kakhi Z, Frisch B, Fournel S, Heurtault B

Int J Pharm. 2019 Mar 14;:

β-Cyclodextrin-functionalized Chitosan/Alginate Compact PolyElectrolyte Complexes (CoPECs) as Functional Biomaterials with Anti-Inflammatory Properties.

Hardy A, Seguin C, Brion A, Lavalle P, Schaaf P, Fournel S, Bourel-Bonnet L, Frisch B, De Giorgi DM

ACS Appl Mater Interfaces. 2018 Aug 14;:

Mimicking the chemistry of natural eumelanin synthesis: the KE sequence in polypeptides and in proteins allows for a specific control of nanosized functional polydopamine formation.

Bergthold C, Hauser D, Chaumont A, El Yakhlifi S, Mateescu M, Meyer F, Metz-Boutigue MH, Frisch B, Schaaf P, Ihiawakrim D, Ersen O, Monnier CA, Petri-Fink A, Rothen-Rutishauser B, Ball V

Biomacromolecules. 2018 Jul 30;:

Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes.

Chekkat N, Lombardo CM, Seguin C, Lechner MC, Dufour F, Nominé Y, De Giorgi M, Frisch B, Micheau O, Guichard G, Altschuh D, Fournel S

Oncotarget. 2018 Mar 20;9(21):15566-15578

Step-by-step build-up of covalent poly(ethylene oxide) nanogel films.

Zahouani S, Hurman L, De Giorgi M, Vigier-Carrière C, Boulmedais F, Senger B, Frisch B, Schaaf P, Lavalle P, Jierry L

Nanoscale. 2017 Nov 30;9(46):18379-18391

D-Cateslytin, a new antimicrobial peptide with therapeutic potential.

Zaet A, Dartevelle P, Daouad F, Ehlinger C, Quilès F, Francius G, Boehler C, Bergthold C, Frisch B, Prévost G, Lavalle P, Schneider F, Haïkel Y, Metz-Boutigue MH, Marban C

Sci Rep. 2017 Nov 9;7(1):15199

Enhancing tumor specific immune responses by transcutaneous vaccination.

Saliba H, Heurtault B, Bouharoun-Tayoun H, Flacher V, Frisch B, Fournel S, Chamat S

Expert Rev Vaccines. 2017 Sep;:

Performance of Pyridylthiourea-Polyethylenimine Polyplex for siRNA-Mediated Liver Cancer Therapy in Cell Monolayer, Spheroid, and Tumor Xenograft Models.

Gossart JB, Pascal E, Meyer F, Heuillard E, Gonçalves M, Gossé F, Robinet E, Frisch B, Seguin C, Zuber G

Glob Chall. 2017 Jul 14;1(4):1700013

Solubilization of α-galactosylceramide in aqueous medium: impact on Natural Killer T cell activation and antitumor responses.

Macho-Fernandez E, Chekkat N, Ehret C, Thomann JS, De Giorgi M, Spanedda MV, Bourel-Bonnet L, Betbeder D, Heurtault B, Faveeuw C, Fournel S, Frisch B, Trottein F

Int J Pharm. 2017 Jul;:

Coupling of Ligands to the Liposome Surface by Click Chemistry.

Spanedda MV, De Giorgi M, Hassane FS, Schuber F, Bourel-Bonnet L, Frisch B

Methods Mol. Biol.. 2017 ;1522:93-106

Exogenous Activation of Invariant Natural Killer T Cells by α-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza.

Barthelemy A, Ivanov S, Hassane M, Fontaine J, Heurtault B, Frisch B, Faveeuw C, Paget C, Trottein F

MBio. 2016 Nov;7(6):

Liposomal constructs for antitumoral vaccination by the nasal route.

Kakhi Z, Frisch B, Heurtault B, Pons F

Biochimie. 2016 Nov;130:14-22

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels.

Beyrath J, Chekkat N, Smulski CR, Lombardo CM, Lechner MC, Seguin C, Decossas M, Spanedda MV, Frisch B, Guichard G, Fournel S

Oncotarget. 2016 10;7(40):64942-64956

N-Heterocyclic Carbene-Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy.

Chekkat N, Dahm G, Chardon E, Wantz M, Sitz J, Decossas M, Lambert O, Frisch B, Rubbiani R, Gasser G, Guichard G, Fournel S, Bellemin-Laponnaz S

Bioconjug. Chem.. 2016 Aug;27(8):1942-8

Airway administration of a highly versatile peptide-based liposomal construct for local and distant antitumoral vaccination.

Kakhi Z, Frisch B, Bourel-Bonnet L, Hemmerlé J, Pons F, Heurtault B

Int J Pharm. 2015 Dec;496(2):1047-56

Smart tools and orthogonal click-like reactions onto small unilamellar vesicles: Additional molecular data.

Vittoria Spanedda M, Salome C, Hilbold B, Berner E, Heurtault B, Fournel S, Frisch B, Bourel-Bonnet L

Data Brief. 2015 Aug 28;5:145-54

Smart tools and orthogonal click-like reactions onto small unilamellar vesicles.

Salomé C, Spanedda MV, Hilbold B, Berner E, Heurtault B, Fournel S, Frisch B, Bourel-Bonnet L

Chem. Phys. Lipids. 2015 May;188:27-36

A new biomimetic route to engineer enzymatically active mechano-responsive materials.

Rios C, Longo J, Zahouani S, Garnier T, Vogt C, Reisch A, Senger B, Boulmedais F, Hemmerle J, Benmlih K, Frisch B, Schaaf P, Jierry L, Lavalle P

Chem Commun (Camb). 2015 Feb 26.

Targeted delivery of alpha-galactosylceramide to CD8alpha+ dendritic cells optimizes type I NKT cell-based antitumor responses.

Macho-Fernandez E, Cruz LJ, Ghinnagow R, Fontaine J, Bialecki E, Frisch B, Trottein F, Faveeuw C

J Immunol. 2014 Jul 15;193(2):961-9

Quantitative measurement of delivery and gene silencing activities of siRNA polyplexes containing pyridylthiourea-grafted polyethylenimines.

Pinel S, Aman E, Erblang F, Dietrich J, Frisch B, Sirman J, Kichler A, Sibler AP, Dontenwill M, Schaffner F, Zuber G

J Control Release. 2014 May 28;182:1-12

On the benefits of rubbing salt in the cut: self-healing of saloplastic PAA/PAH compact polyelectrolyte complexes.

Reisch A, Roger E, Phoeung T, Antheaume C, Orthlieb C, Boulmedais F, Lavalle P, Schlenoff JB, Frisch B, Schaaf P

Adv Mater. 2014 Apr 23;26(16):2547-51

Catalytic Saloplastics: Alkaline Phosphatase Immobilized and Stabilized in Compacted Polyelectrolyte Complexes.

Tirado P, Reisch A, Roger E, Boulmedais F, Jierry L, Lavalle P, Voegel JC, Schaaf P, Schlenoff JB, Frisch B

Adv Funct Mater. 2013 Oct 11;23(38):4785-92.

Self-construction of supramolecular polyrotaxane films by an electrotriggered morphogen-driven process.

Rydzek G, Garnier T, Schaaf P, Voegel JC, Senger B, Frisch B, Haikel Y, Petit C, Schlatter G, Jierry L, Boulmedais F

Langmuir. 2013 Aug;29(34):10776-84

MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes.

Philippe L, Alsaleh G, Pichot A, Ostermann E, Zuber G, Frisch B, Sibilia J, Pfeffer S, Bahram S, Wachsmann D, Georgel P

Ann Rheum Dis. 2013 Jun;72(6):1071-9

Biomimetic cryptic site surfaces for reversible chemo- and cyto-mechanoresponsive substrates.

Bacharouche J, Badique F, Fahs A, Spanedda MV, Geissler A, Malval JP, Vallat MF, Anselme K, Francius G, Frisch B, Hemmerle J, Schaaf P, Roucoules V

ACS Nano. 2013 Apr 23;7(4):3457-65

Modified and derived ethanol injection toward liposomes: development of the process.

Gentine P, Bourel-Bonnet L, Frisch B

J Liposome Res. 2013 Mar;23(1):11-9

Potent calcium phosphate nanoparticle surface coating for in vitro and in vivo siRNA delivery: a step toward multifunctional nanovectors.

Devarasu T, Saad R, Ouadi A, Frisch B, Robinet E, Laquerriere P, Voegel JC, Baumert T, Ogier J, Meyer F

J Mat Chem B. 2013;1(36):4692-700.

Key role for respiratory CD103(+) dendritic cells, IFN-gamma, and IL-17 in protection against Streptococcus pneumoniae infection in response to alpha-galactosylceramide.

Ivanov S, Fontaine J, Paget C, Macho Fernandez E, Van Maele L, Renneson J, Maillet I, Wolf NM, Rial A, Leger H, Ryffel B, Frisch B, Chabalgoity JA, Sirard JC, Benecke A, Faveeuw C, Trottein F

J Infect Dis. 2012 Sep 1;206(5):723-34

Novel glycolipid TLR2 ligands of the type Pam2Cys-alpha-Gal: synthesis and biological properties.

Thomann JS, Monneaux F, Creusat G, Spanedda MV, Heurtault B, Habermacher C, Schuber F, Bourel-Bonnet L, Frisch B

Eur J Med Chem. 2012 May;51:174-83

Activation of invariant Natural Killer T lymphocytes in response to the alpha-galactosylceramide analogue KRN7000 encapsulated in PLGA-based nanoparticles and microparticles.

Macho Fernandez E, Chang J, Fontaine J, Bialecki E, Rodriguez F, Werkmeister E, Krieger V, Ehret C, Heurtault B, Fournel S, Frisch B, Betbeder D, Faveeuw C, Trottein F

Int J Pharm. 2012 Feb 14;423(1):45-54

Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo.

Creusat G, Thomann JS, Maglott A, Pons B, Dontenwill M, Guérin E, Frisch B, Zuber G

J Control Release. 2012 Feb;157(3):418-26

Cyto-mechanoresponsive polyelectrolyte multilayer films.

Davila J, Chassepot A, Longo J, Boulmedais F, Reisch A, Frisch B, Meyer F, Voegel JC, Mesini PJ, Senger B, Metz-Boutigue MH, Hemmerle J, Lavalle P, Schaaf P, Jierry L

J Am Chem Soc. 2012 Jan 11;134(1):83-6

Morphogen-driven self-construction of covalent films built from polyelectrolytes and homobifunctional spacers: buildup and pH response.

Rydzek G, Polavarapu P, Rios C, Tisserant JN, Voegel JC, Senger B, Lavalle P, Frisch B, Schaaf P, Boulmedais F, Jierry L

. 2012;8(40):10336-43.

One-pot morphogen driven self-constructing films based on non-covalent host-guest interactions.

Rydzek G, Parat A, Polavarapu P, Baehr C, Voegel JC, Hemmerle J, Senger B, Frisch B, Schaaf P, Jierry L, Boulmedais F

. 2012;8(2):446-53.

Benzophenone-containing fatty acids and their related photosensitive fluorescent new probes: design, physico-chemical properties and preliminary functional investigations.

Hilbold B, Perrault M, Ehret C, Niu SL, Frisch B, Pecheur EI, Bourel-Bonnet L

Bioorg Med Chem. 2011 Dec 15;19(24):7464-73

Characterization of the mechanisms of HIV-1 Vpr(52-96) internalization in cells.

Greiner VJ, Shvadchak V, Fritz J, Arntz Y, Didier P, Frisch B, Boudier C, Mely Y, de Rocquigny H

Biochimie. 2011 Oct;93(10):1647-58

Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting.

Thomann JS, Heurtault B, Weidner S, Braye M, Beyrath J, Fournel S, Schuber F, Frisch B

Biomaterials. 2011 Jul;32(20):4574-83

Electrochemically triggered assembly of films: a one-pot morphogen-driven buildup.

Rydzek G, Jierry L, Parat A, Thomann JS, Voegel JC, Senger B, Hemmerle J, Ponche A, Frisch B, Schaaf P, Boulmedais F

Angew Chem Int Ed Engl. 2011 May 2;50(19):4374-7

Spleen-resident CD4+ and CD4- CD8alpha- dendritic cell subsets differ in their ability to prime invariant natural killer T lymphocytes.

Bialecki E, Macho Fernandez E, Ivanov S, Paget C, Fontaine J, Rodriguez F, Lebeau L, Ehret C, Frisch B, Trottein F, Faveeuw C

PLoS One. 2011;6(10):e26919

Covalent layer-by-layer assemblies of polyelectrolytes and homobifunctional spacers.

El Haitami AE, Thomann JS, Jierry L, Parat A, Voegel JC, Schaaf P, Senger B, Boulmedais F, Frisch B

Langmuir. 2010 Jul 20;26(14):12351-7.

Liposomes as delivery systems for nasal vaccination: strategies and outcomes.

Heurtault B, Frisch B, Pons F

Expert Opin Drug Deliv. 2010 Jul;7(7):829-44.

Nucleic acid transfer with hemifluorinated polycationic lipids.

Klein E, Leborgne C, Ciobanu M, Klein J, Frisch B, Pons F, Zuber G, Scherman D, Kichler A, Lebeau L

Biomaterials. 2010 Jun;31(17):4781-8

Protein adsorption on dopamine-melanin films: role of electrostatic interactions inferred from zeta-potential measurements versus chemisorption.

Bernsmann F, Frisch B, Ringwald C, Ball V

J Colloid Interface Sci. 2010 Apr 1;344(1):54-60

Novel powerful water-soluble lipid immunoadjuvants inducing mouse dendritic cell maturation and B cell proliferation using TLR2 pathway.

Spanedda MV, Heurtault B, Weidner S, Baehr C, Boeglin E, Beyrath J, Milosevic S, Bourel-Bonnet L, Fournel S, Frisch B

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1869-72

"HFP" fluorinated cationic lipids for enhanced lipoplex stability and gene delivery.

Klein E, Ciobanu M, Klein J, Machi V, Leborgne C, Vandamme T, Frisch B, Pons F, Kichler A, Zuber G, Lebeau L

Bioconjug Chem. 2010 Feb 17;21(2):360-71.

Polymer multilayer films obtained by electrochemically catalyzed click chemistry.

Rydzek G, Thomann JS, Ben Ameur N, Jierry L, Mésini P, Ponche A, Contal C, El Haitami AE, Voegel JC, Senger B, Schaaf P, Frisch B, Boulmedais F

Langmuir. 2010 Feb;26(4):2816-24

Conjugation of ligands to the surface of preformed liposomes by click chemistry.

Frisch B, Hassane FS, Schuber F

Methods Mol Biol. 2010;605:267-77.

Multifunctional Stretchable Plasma Polymer Modified PDMS Interface for Mechanically Responsive Materials

Geissler A, Vallat MF, Fioux P, Thomann JS, Frisch B, Voegel JC, Hemmerle J, Schaaf P, Roucoules V

Plasma Process Polym. 2010 Jan 14;7(1):64-77

Rational design and immunogenicity of liposome-based diepitope constructs: application to synthetic oligosaccharides mimicking the Shigella flexneri 2a O-antigen.

Said Hassane F, Phalipon A, Tanguy M, Guerreiro C, Belot F, Frisch B, Mulard LA, Schuber F

Vaccine. 2009 Aug 27;27(39):5419-26

The effect of microstructured surfaces and laminin-derived peptide coatings on soft tissue interactions with titanium dental implants.

Werner S, Huck O, Frisch B, Vautier D, Elkaim R, Voegel JC, Brunel G, Tenenbaum H

Biomaterials. 2009 Apr;30(12):2291-301

Specific and non-specific phagocytosis of ligand-grafted PLGA microspheres by macrophages.

Brandhonneur N, Chevanne F, Vie V, Frisch B, Primault R, Le Potier MF, Le Corre P

Eur J Pharm Sci. 2009 Mar 2;36(4-5):474-85

Design of a liposomal candidate vaccine against Pseudomonas aeruginosa and its evaluation in triggering systemic and lung mucosal immunity.

Heurtault B, Gentine P, Thomann JS, Baehr C, Frisch B, Pons F

Pharm Res. 2009 Feb;26(2):276-85

The 'co-delivery' approach to liposomal vaccines: application to the development of influenza-A and hepatitis-B vaccine candidates.

Laing P, Bacon A, McCormack B, Gregoriadis G, Frisch B, Schuber F

J Liposome Res. 2006;16(3):229-35.

Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells.

Espuelas S, Roth A, Thumann C, Frisch B, Schuber F

Mol Immunol. 2005 Apr;42(6):721-9.

Induction of effective and antigen-specific antitumour immunity by a liposomal ErbB2/HER2 peptide-based vaccination construct.

Roth A, Rohrbach F, Weth R, Frisch B, Schuber F, Wels WS

Br J Cancer. 2005 Apr 25;92(8):1421-9.

Primary cell adhesion on RGD-functionalized and covalently crosslinked thin polyelectrolyte multilayer films.

Picart C, Elkaim R, Richert L, Audoin T, Arntz Y, Cardoso MD, Schaaf P, Voegel JC, Frisch B

Adv Funct Mater. 2005 Jan;15(1):83-94.

Polyelectrolyte multilayer films with pegylated polypeptides as a new type of anti-microbial protection for biomaterials.

Boulmedais F, Frisch B, Etienne O, Lavalle P, Picart C, Ogier J, Voegel JC, Schaaf P, Egles C

Biomaterials. 2004 May;25(11):2003-11.