Fiche publication
Date publication
juin 2026
Journal
Parasites & vectors
Auteurs
Membres identifiés du Cancéropôle Est :
Dr RIALLAND Mickaël
,
Mr PERNET Nicolas
Tous les auteurs :
Bourbon L, Dusuel A, Pernet N, Rialland M, Roche B, Faivre B, Sorci G
Lien Pubmed
Résumé
Parasitic helminths modulate host immunity to establish chronic infections, often expanding regulatory T cells (Tregs) to suppress inflammation. However, how helminths adjust immunomodulation during coinfection with fast-replicating microparasites remains unclear. Here, we investigated the immune modulation dynamics in a murine model coinfected with the nematode Heligmosomoides polygyrus (Hp) and the protozoan Plasmodium yoelii (Py).
Mots clés
Excretory–secretory products, Experimental evolution, Helminth immunomodulation, Nematode–malaria coinfection, Regulatory T cells
Référence
Parasit Vectors. 2026 06 13;:
