Fiche publication
Date publication
avril 2026
Journal
STAR protocols
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BARBERI-HEYOB Muriel
,
Dr PINEL Sophie
,
Dr RECH Fabien
,
Dr DAOUK Joël
Tous les auteurs :
Schneller P, Pierson J, Daouk J, Rech F, Doyen M, Pinel S, Barberi-Heyob M
Lien Pubmed
Résumé
We present a protocol to develop a syngeneic surgical glioblastoma model using F98 cells in Fischer F344 rats. This model recapitulates tumor growth, surgical resection, and recurrence observed in patients. We describe procedures for F98 cell preparation, stereotactic implantation, MRI-guided tumor resection, and longitudinal MRI monitoring. This protocol provides a clinically relevant platform to investigate post-resection tumor recurrence and evaluate therapeutic strategies targeting residual disease.
Mots clés
Biotechnology and bioengineering, Cancer, Clinical Protocol
Référence
STAR Protoc. 2026 04 17;7(2):104503
