Fiche publication
Date publication
mars 2026
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques
,
Dr LHERMITTE Benoît
,
Dr BUND Caroline
Tous les auteurs :
Bund C, Todeschi J, Lhermitte B, Namer IJ
Lien Pubmed
Résumé
We report the case of a 52-year-old man who presented with a diffuse, nonenhancig right frontotemporal lesion on MRI, without a solid component. Neither FDG nor FDOPA PET/MR was able to identify a hypermetabolic focus to guide the biopsy, but photopenic defect. Stereotactic biopsy performed at the temporal region revealed a IDH wild-type glioblastoma with a Ki-67 index below 1%. Seven months after biopsy, aggressive tumor growth was observed around the biopsy tract, with a solid enhancing mass and very high FDOPA and FDG uptake, typical for a glioblastoma. The patient died 28 months after diagnosis.
Mots clés
FDG, FDOPA, HRMAS NMR spectroscopy, biopsy tract, glioblastoma, photopenic defect
Référence
Clin Nucl Med. 2026 03 25;:
