Fiche publication


Date publication

août 2014

Journal

Schizophrenia research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HAFFEN Emmanuel


Tous les auteurs :
Briki M, Monnin J, Haffen E, Sechter D, Favrod J, Netillard C, Cheraitia E, Marin K, Govyadovskaya S, Tio G, Bonin B, Chauvet-Gelinier JC, Leclerc S, Hodé Y, Vidailhet P, Berna F, Bertschy AZ, Vandel P

Résumé

A psychotherapeutic approach for schizophrenia is now recommended as an adjuvant for psychopharmacology, since antipsychotic medications only have a partial impact especially as regards positive symptoms and insight. In addition, cognitive distortions and the lack of metacognitive skills might increase positive symptoms leading to poor social functioning. This underlines the need for specific approaches which target cognitive processes relevant for insight, and abilities in metacognition. Metacognitive training (MCT) is a structured group intervention, which enhances a patient's reflection on cognitive biases and improves problem-solving. The aim of our study was to assess MCTs' short term impact on insight, symptoms and quality of life. Fifty patients with schizophrenia or schizoaffective disorders and persistent positive symptoms (delusions or hallucinations) were enrolled in the study. After baseline assessment participants were randomised either to supportive therapy or MCT. Both groups used the same design (1h-session twice a week during 8weeks) although the basic knowledge given to participants was different between interventions. Participants were assessed at eight weeks based on the Scale to Assess Unawareness of Mental Disorder, Positive and Negative Syndrome Scale (PANSS), Psychotic Symptom Rating Scales, the Calgary Depression Scale for Schizophrenia and the Quality of Life Scale. Between-group differences were significant in favour of MCT on the PANSS positive scale. Between-group differences in post- and pre-test values showed a trend in favour of MCT for insight on hallucinations. Results of our study indicate that the MCT has an effect on reducing positive symptomatology, and a trend impact on insight and social functioning.

Mots clés

Adult, Cognitive Therapy, methods, Delusions, physiopathology, Female, France, Hallucinations, physiopathology, Humans, Male, Psychiatric Status Rating Scales, Psychotic Disorders, physiopathology, Quality of Life, Schizophrenia, physiopathology, Schizophrenic Psychology, Social Adjustment, Thinking, Time Factors, Treatment Outcome

Référence

Schizophr. Res.. 2014 Aug;157(1-3):99-106