Fiche publication
Date publication
mars 2026
Journal
Autoimmunity reviews
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BOUVIER Anne-Marie
,
Dr JOOSTE Valérie
Tous les auteurs :
Pillot V, Toquet S, Charuel JL, Tansley S, Boussouar S, Brillet PY, Lu H, Vellas D, Boulahfa ST, Louis SL, Uzunhan Y, Belle A, Cohen P, Ghillani-Dalbin P, Miyara M, Hie M, Foulon G, Gambier N, Boitiaux JF, Fuzibet P, Crestani B, Baudelet L, Ilzkovitz M, Nagant C, Bouvier AM, Jooste V, Benveniste O, Allenbach Y
Lien Pubmed
Résumé
Antisynthetase syndrome (ASyS) is a systemic autoimmune disease that primarily affects the lungs, joints, and muscles, and is associated in over 90% of cases with anti-Jo-1, anti-PL7, or anti-PL12 antibodies. ASyS is not associated with malignancy. Anti-OJ autoantibody-positive ASyS is poorly characterized, as it is a rare anti-synthetase antibody and commercial immunoassay kits lack reliability.
Mots clés
Aminoacyl-tRNA synthetases, Anti-OJ antibody, Interstitial, Lung diseases, Myositis, Neoplasms
Référence
Autoimmun Rev. 2026 03 11;:104032
